The Research on Establishment of “Clinical Practice Guide of Blood Specimen Collection, Preservation and Delivery for Clinical Nurse”: Protocol Description

INTRODUCTION AND OBJECTIVE: The correctness of the blood test is closely related to the sample. According to the recent reported data, 80 percentage unsatisfactory results of the clinical test are due to the poor quality of sample, especially the blood sample. Clinical practice guide (CPG) is directly to instruct the clinical nursing practice. And the recommendations in the clinical practice guide are based on the best available study evidences. There is lack of CPG about blood sample specimen collection, preservation and delivery (BSCPD) in China. Additionally, related published clinical studies are accumulated in a great deal. Therefore, establishing a CPG is necessarily and practicable. The detailed objectives are: 1) to describe and analyze the research status of BSCPD in China; 2) to describe and analyze the practice status of BSCPD in China; 3) to systematic appraise the available evidences of BSCPD; 4) to establish the clinical practice guide of BSCPD; 5) to judge the clinical practice guide of BSCPD. METHODS: Objective 1): Bibliometric analysis is applied, the database include China National Knowledge Infrastructure Database (CNKI) and Sino-med and the research period is from the year of 2003 to 2013; Objective 2): Questionnaire survey for all the registered clinical nurses in a grade three hospital; objective 3): Systematic review according to Cochrane collaboration handbook 5.1.0 is applied which includes assessment of risk of bias, data extraction, data analysis; Objective 4) and 5): Using the appraising guidelines research and evaluation (AGREE) to evaluate of the draft of CPG of BSCPD. RESULTS: Bibliometric analysis started in 2013, and search strategies have been established. Questionnaire survey setting and depth interviewees have been identified and communicated. CONCLUSIONS: The CPG of BSCPD will serve as an important resource in instructing and modifying clinical nursing practice. Given this CPG of BSCPD will be a draft version, the applicability and suitability of it will need a further evaluated in the real clinical nursing world

Anti-tumor effect of polysaccharides from rhizome of Curculigo orchioides Gaertn on cervical cancer

Purpose: To investigate the anti-tumor effects of polysaccharides from Curculigo orchioides (PDC) on cervical cancer and the possible mechanisms involved.Methods: A Box–Behnken design (BBD) was employed to optimize extraction conditions for PDC. The anti-tumor effect of PDC on cervical cancer was investigated in vivo in mice injected with Hela cells. The parameters measured were tumor volume and weight. In vitro anti-tumor effects of PDC were assessed by measuring expressions of caspase-3, caspase-9 and P53 proteins in Hela cells via ELISA assay. Thymus and spleen indices were calculated for assessment of PDC effect on immune function.Results: The optimum extraction conditions predicted by the response surface methodology (RSM) were: extraction time = 1.58 h, ratio-of-water-to-sample = 30.05 mL/g and extraction number = 1.95. PDC showed significant anti-tumor effect on cervical cancer in mice. It significantly increased thymus and spleen indices in mice; and significantly up-regulated expressions of caspase-3, caspase-9 and P53 proteins in HeLa cells.Conclusion: PDC has significant anti-tumor effect on cervical cancer in vivo and in vitro, most probably through mechanisms involving enhancement on immune function and induction of apoptosis.Keyword: Curculigo orchioides, Polysaccharides, Cervical cancer, HeLa cells, Apoptosi

Angular Reconstruction of a Lead Scintillating-Fiber Sandwiched Electromagnetic Calorimeter

A new method called Neighbor Cell Deposited Energy Ratio (NCDER) is proposed to reconstruct incidence position in a single layer for a 3-dimensional imaging electromagnetic calorimeter (ECAL).This method was applied to reconstruct the ECAL test beam data for the Alpha Magnetic Spectrometer-02 (AMS-02). The results show that this method can achieve an angular resolution of 7.36\pm 0.08 / \sqrt(E) \oplus 0.28 \pm 0.02 degree in the determination of the photons direction, which is much more precise than that obtained with the commonly-adopted Center of Gravity(COG) method (8.4 \pm 0.1 /sqrt(E) \oplus 0.8\pm0.3 degree). Furthermore, since it uses only the properties of electromagnetic showers, this new method could also be used for other type of fine grain sampling calorimeters.Comment: 6 pages, 8 figure

Cloth interactive transformer for virtual try-on

The 2D image-based virtual try-on has aroused increased interest from the multimedia and computer vision fields due to its enormous commercial value. Nevertheless, most existing image-based virtual try-on approaches directly combine the person-identity representation and the in-shop clothing items without taking their mutual correlations into consideration. Moreover, these methods are commonly established on pure convolutional neural networks (CNNs) architectures which are not simple to capture the long-range correlations among the input pixels. As a result, it generally results in inconsistent results. To alleviate these issues, in this paper, we propose a novel two-stage cloth interactive transformer (CIT) method for the virtual try-on task. During the first stage, we design a CIT matching block, aiming to precisely capture the long-range correlations between the cloth-agnostic person information and the in-shop cloth information. Consequently, it makes the warped in-shop clothing items look more natural in appearance. In the second stage, we put forth a CIT reasoning block for establishing global mutual interactive dependencies among person representation, the warped clothing item, and the corresponding warped cloth mask. The empirical results, based on mutual dependencies, demonstrate that the final try-on results are more realistic. Substantial empirical results on a public fashion dataset illustrate that the suggested CIT attains competitive virtual try-on performance

Light adaptation strategies of Quercus mongolica at different ages in four plantations

This study investigated the allocation strategies of non-structural carbohydrates and functional traits in Quercus mongolica seedlings of different ages under different light conditions. The study took place at the Urban Forestry Demonstration Base in Harbin City, Heilongjiang Province, China. Seedlings of three age classes were collected in two light environments, the forest edge and the forest understory. By measuring specific leaf area, biomass, soluble sugar concentration and starch concentration, we revealed the growth adaptation strategies and responses to different light conditions in Q. mongolica seedlings of different age classes. Our results show that the adaptation strategies of seedlings of different age classes are very different. First, our study showed a strong coordination of soluble sugars between roots, stems, and leaves of 1−2 year old Q. mongolica seedlings, indicating an efficient partitioning of carbon between organs at this age. In 3−4 year old Q. mongolica seedlings, a significant negative correlation was observed between starch in the roots and soluble sugars in the leaves, indicating the transformation of various non-structural carbohydrates. In addition, 5−6 year old seedlings start to increase their investment in the above-ground part to achieve a height advantage. In conclusion, this study improves our understanding of the light adaptation strategies of Q. mongolica seedlings and provides valuable insights for the natural regeneration and management of Q. mongolica forest vegetation

Barriers to Research Utilization among Registered Nurses in Traditional Chinese Medicine Hospitals: A Cross-Sectional Survey in China

Background. As there might be relevant differences with regard to research utilization in the general hospitals, we aimed to study research utilization among registered nurses working in traditional Chinese medicine hospitals. Methods. A total of 648 registered nurses from 4 tertiary-level hospitals in China were recruited for participation. A modified BARRIERS Scale and self-designed questionnaires were used for data collection. Data were analyzed with descriptive statistics, t-tests, and one-way ANOVAs and Spearman correlation analysis. Results. Overall, items which belong to the subscale “Research” were identified as the most important barriers. Among the individual items, the lack of time on the job was ranked as the top barrier, followed by the lack of knowledgeable colleagues and by overwhelming research publications. Clinical experience, working pressure, job satisfaction, and research experience could be identified as associated factors for barriers to research utilization. Conclusions. Registered nurses in traditional Chinese medicine hospitals felt high barriers to research utilization. Reducing registered nurses’ working pressure, promoting their positive attitude to nursing, and improving research training might be helpful for increasing research utilization. Close cooperation between clinical and nursing schools or academic research centres might facilitate the necessary change in nursing education and routine