DEVELOPMENT OF ENTREPRENEURIAL ACTIVITIES â€" PREMISE OF THE INCREASE OF ECONOMIC COMPETITIVENESS

In the context of the integration into the European Union, the issue of the increase of firmsâ€(tm) competitiveness has become essential for Romaniaâ€(tm)s economy also, which requires as a mandatory condition the elaboration and application of certain clear strategies, both at the level of firms, and of the Government's, with specific goals and actions. Although it has made certain progress, Romania has significant competitiveness delays compared to the EU member states. In this context, development of entrepreneurial activities is a premise of the increase of economic competitiveness. Entrepreneurship is first of all a state of mind referring to the motivation and capacity of an individual to identify opportunity and follow it with the purpose of producing value or economic success.entrepreneurship, competitiveness, development

GENDER DISPARITIES IN THE ENTREPRENEURIAL FIELD IN WESTERN ROMANIA

The entrepreneurial spirit may develop in any economic sector and any type of business, both in the case of men and women, it is applied to a wide range of organisations, from family businesses to large companies, irrespective of the structure of shareholders, from NGOs to companies gone public on the capital market, firms from all sectors of activity. As regards the gender disparities in the entrepreneurial field, studies reveal the fact that although the two genders are similar, women entrepreneurs differ from men through motivations, their business ability and occupational past. Although the gender differences are still important, the number of women entrepreneurs has significantly increased compared to the previous period.entrepreneurship, gender disparities, motivations

Anti-inflammatory activity of Adenoprosin in nonbacterial prostatitis

Background: The treatment of chronic nonbacterial prostatitis remains an unexplained urology problem. Adenoprosin is a new entomological product containing lipoprotein extract of Lepidopteran insect species. Laboratory studies of the product have shown that it possesses antioxidant, antiproliferative and anti-inflammatory properties. Material and methods: Nonbacterial prostatitis was experimentally modeled on 100 white Wistar rats. Adenoprosin, 150 mg rectal suppositories, was tested against the reference product Vitaprost, 50 mg rectal suppositories and placebo on both the aseptic acute and chronic non-bacterial prostatitis models. In the acute prostatitis model, treatment lasted 7 days and in chronic prostatitis 15 days. The treatment efficacy criteria consisted of assessment of the general condition and histological results. Results: In rats receiving Adenoprosin, the microscopic image of the prostate showed a decrease in the severity of the inflammatory process, in both acute aseptic and chronic nonbacterial prostatitis, manifested by the recovery on the surface of the epithelial cells in the stromal area of the prostate, and decrease in vascular congestion and number of acini with desquamated epithelium. Conclusions: The product of entomological origin Adenoprosin, showed an obvious anti-inflammatory effect in the experimental model of aseptic acute or chronic non-bacterial prostatitis induced on Wistar white rats, similar to the Vitaprost reference product, and significant compared to placebo (p<0.05)

Benign prostatic hyperplasia - etiology, clinical features and management. Historical and contemporary aspects

Introduction. Benign prostatic hyperplasia and chronic prostatitis are the most common conditions in men, the frequency of which varies with age. Chronic prostatitis (infectious or inflammatory) has a frequency of 8-35% in patients aged 20-50 years, reaching a maximum of 60-70% in those aged over 50 years. Materials and methods. Materials for the study served the medical literature regarding benign prostatic hyperplasia and chronic inflammation, published in the local and international scientific journals. Scientific databases like Cochrane Library, Medline, Scopus, Medicus, NCBI, PubMed, Google Scholar were used to find the necessary articles. Research methods – analysis, synthesis, systematization, and description. Results. After analyzing the available data, a review of the literature was conducted which highlighted both the strong and weak points of the historical medical approaches to addressing benign prostatic hyperplasia, as well as the ontogenetics and anatomical characteristics of the prostate gland. This included examining the incidence rates, concepts of causation and development, principles of diagnosis and classification of benign prostatic hyperplasia. The review also revealed the pros and cons of using mini-invasive treatment strategies versus traditional transvesical approaches in treating this condition, as well as the ongoing and significant socioeconomic impact in underdeveloped countries. Conclusions. There remains the issue of reducing intra- and post-operative complications after benign prostatic hyperplasia surgery, especially a voluminous one, which imposes itself as a very critical problem in the development of an effective treatment strategy. For the first time, a problem was described by assessing the particularities of some biochemical criteria at local surgical site and in blood serum, histological - at the level of nodular prostatic hyperplasia and at the border of the surgical site. This requires a complex correlational study to assess the biochemical, histological and immunohistochemical parameters, including the evaluation of the associations or coexistence of benign prostatic hyperplasia and chronic prostatitis

Rolul nefrolitotomiei percutanate în tratamentul litiazei renale

Summary. Retrospective analysis of the results of NLP to establish the correct therapeutic indications. In the study was included 79 patients with urolithiasis undergoing PCNL in 2011 year. The success of the method was 78.5%, procedure failure was due to intraoperation complications and was necessary to repeat the procedure or to use another method of treatment. The rate of minor complication was 18.5%, the most diffi cult major complication was 2.52%: perforation of the colonum and paranephral urinoma. Conclusions: in the multimodal aproach of urolithiasis PCNL is indispensable method of treatement; PCNL is effective method in the treatement of diferent types of kidney stones, the major avantage of this miniinvasive method are important in diffi cult situations, (complex stones). Major complications are no so frequent, we must put immediate diagnosis and immediate action if this complications apears.Rezumat. Scopul lucrării a fost analiza retrospectivă a rezultatelor NLP în vederea stabilirii indicaţiilor terapeutice corecte. A fost studiat un lot de 79 de pacienţi la care s-a efectuat NLP pentru litiază renală pe parcursul anului 2011. Succesul metodei a fost de 78.5%, eşecul procedurii a fost cauzat de complicaţii intraoperatorii care au impus repetarea procedurii sau recurgerea la altă metodă de tratament. Rata complicaţiilor minore a fost de 18.5%, cele majore: perforaţie de colon şi urinom paranefral s-au întâlnit în 2.52% cazuri. În concluzie, nefrolitotomia percutanată este o intervenţie indispensabilă terapiei multimodale a litiazei renale. NLP este o metodă efi cientă în rezolvarea diferitelor tipuri de litiază renală, benefi ciile majore ale acestei metode miniinvazive sânt remarcate mai ales în cazurile difi cile (litiază complexă). Complicaţiile majore, deşi rare, sunt redutabile şi necesită depistare timpurie şi acţiune fermă în cazul apariţiei lor.Резюме. Цель работы – pетроспективный анализ результатов ЧНЛТ, с целью определения правильных показаний к терапии. В исследование были включены 79 пациентов с мочекаменной болезнью, перенесших ЧНЛТ в 2011 году. Успех метода был зафиксирован в 78.5% случаев, неудачи были связаны с интраоперационными осложнениями, которые вызвали необходимость повторения процедуры или применения других методов лечения. Частота незначительных осложнений составила 18.5%, частота серъезных осложнений, таких как: перфорация толстого кишечника и околопочечного мочевого затека, составила 2.52%. Чрескожная нефролитотомия является незаменимым методом в комплексном лечении мочекаменной болезни почек. ЧНЛТ является эффективным методом разрешения различных типов почечных камней, основные преимущества этого миниинвазивного метода зафиксированы особенно в сложных случаях (сложные камни почек). Серъезные осложнения, будучи редкими, являются значимыми и требуют ранней диагностики и решительных действий

Disfuncţia erectilă: protocol clinic național PCN-261

USMF „Nicolae Testemițanu”, IMSP Spitalul Clinic RepublicanAcest protocol a fost elaborat de grupul de lucru al Ministerului Sănătăţii al Republicii Moldova (MS RM), constituit din reprezentanţii catedrei Urologie şi Nefrologie Chirurgicală a Universităţii de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” şi IMSP Spitalul Clinic Republican (Chişinău, Republica Moldova). Protocolul naţional este elaborat în conformitate cu sursele ştiinţifice contemporane privind conduita pacientului cu disfuncţie erectilă. Recomandările şi algoritmii expuşi corespund principiilor medicinii bazate pe dovezi şi va servi drept bază pentru elaborarea protocoalelor instituţionale. La recomandarea MS RM, pentru monitorizarea protocoalelor instituţionale pot fi folosite formulare suplimentare, care nu sunt incluse în protocolul clinic naţiona

Insuficienţă renală cronică terminală sub dializă: protocol clinic naţional PCN-87

Acest protocol a fost elaborat de grupul de lucru al Ministerului Sănătăţii al Republicii Moldova (MS RM), constituit din reprezentanţii Catedrei Urologie şi Nefrologie chirurgicală a Universităţii de Stat de Medicină şi Farmacie “Nicolae Testemiţanu” şi Centrului de Dializă şi Transplant renal al Spitalului Clinic Republican (Chişinău, Republica Moldova), în colaborare cu Programul Preliminar de Ţară al Fondului Provocările Mileniului pentru Buna Guvernare, finanţat de Guvernul SUA prin Corporaţia Millenium Challenge Corporation şi administrat de Agenţia Statelor Unite ale Americii pentru Dezvoltare Internaţională. Protocolul clinic naţional este elaborat în conformitate cu ghidurile internaţionale actuale privind managementul pacienţilor cu insuficienţă renală cronică terminală şi va servi drept bază pentru elaborarea protocoalelor instituţionale. La recomandarea MS RM, pentru monitorizarea protocoalelor instituţionale pot fi folosite formulare suplimentare, care nu sunt incluse în protocolul clinic naţional

Prostatita acută şi cronică: protocol clinic naţional PCN-262

USMF „Nicolae Testemițanu”, IMSP Spitalul Clinic RepublicanAcest protocol a fost elaborat de grupul de lucru al Ministerului Sănătăţii al Republicii Moldova (MS RM), constituit din reprezentanţii catedrei Urologie şi Nefrologie Chirurgicală a Universităţii de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” şi IMSP Spitalul Clinic Republican (Chişinău, Republica Moldova). Protocolul naţional este elaborat în conformitate cu sursele ştiinţifice contemporane privind conduita pacientului în prostatita acută şi cronică. Recomandările şi algoritmii expuşi corespund principiilor medicinii bazate pe dovezi şi va servi drept bază pentru elaborarea protocoalelor instituţionale. La recomandarea MS RM, pentru monitorizarea protocoalelor instituţionale pot fi folosite formulare suplimentare, care nu sunt incluse în protocolul clinic naţional