インドネシア産フトモモ科植物Baeckea frutescens由来の新規化合物の単離・構造決定と抗菌活性及び細胞毒性

富山大学・富医薬博甲216号・Khoirun Nisa・2016/9/7This doctoral thesis summarizes the full contents of the following publications.1) Nisa, K.; Ito, T.; Subehan.; Matsui, T.; Kodama, T.; Morita, H. New acylphloroglucinol derivatives from the leaves of Baeckea frutescens. Phytochemistry Letter 2016, 15, 42–45.2) Nisa, K.; Ito, T.; Kodama, T.; Tanaka, M.; Okamoto, Y.; Asakawa, Y.; Imagawa, H.; Morita, H. New cytotoxic phloroglucinols, baeckenones D–F, from the leaves of Indonesian Baeckea frutescens. Fitoterapia 2016, 109, 236–240.3) Ito, T.; Nisa, K.; Kodama, T.; Tanaka, M.; Okamoto, Y.; Ismail.; Morita, H. Two new cyclopentenones and a new furanone from Baeckea frutescens and their cytotoxicities. Fitoterapia 2016, 112, 132–135.富山大

Fluctuation Theorem of Information Exchange within an Ensemble of Paths Conditioned on Correlated-Microstates

Fluctuation theorems are a class of equalities that express universal properties of the probability distribution of a fluctuating path functional such as heat, work or entropy production over an ensemble of trajectories during a non-equilibrium process with a well-defined initial distribution. Jinwoo and Tanaka (Jinwoo, L.; Tanaka, H. Sci. Rep. 2015, 5, 7832) have shown that work fluctuation theorems hold even within an ensemble of paths to each state, making it clear that entropy and free energy of each microstate encode heat and work, respectively, within the conditioned set. Here we show that information that is characterized by the point-wise mutual information for each correlated state between two subsystems in a heat bath encodes the entropy production of the subsystems and heat bath during a coupling process. To this end, we extend the fluctuation theorem of information exchange (Sagawa, T.; Ueda, M. Phys. Rev. Lett. 2012, 109, 180602) by showing that the fluctuation theorem holds even within an ensemble of paths that reach a correlated state during dynamic co-evolution of two subsystems.Comment: 8 pages, 2 figure

Lymphangiogenesis in myocardial remodelling after infarction

Ishikawa Y, Akishima-Fukasawa Y, Ito K, Akasaka Y, Tanaka M, Shimokawa R, Kimura-Matsumoto M, Morita H, Sato S, Kamata I & Ishii T (2007) Histopathology51, 345–35

Lie Derivatives of the Shape Operator of a Real Hypersurface in a Complex Projective Space

This work was supported by MINECO-FEDER Project MTM 2016-78807-C2-1-P.We consider real hypersurfaces M in complex projective space equipped with both the Levi-Civita and generalized Tanaka–Webster connections. Associated with the generalized Tanaka–Webster connection we can define a differential operator of first order. For any nonnull real number k and any symmetric tensor field of type (1,1) B on M, we can define a tensor field of type (1,2) on M, B(k) T , related to Lie derivative and such a differential operator. We study symmetry and skew symmetry of the tensor A(k) T associated with the shape operator A of M.MINECO-FEDER Project MTM 2016-78807-C2-1-

Concentration Dependence of the Flory Chi Parameter within Two-State Models

The Flory chi parameter is typically assumed to depend only on the temperature, T. Experimental results often require the replacement of this chi(T) by chieff, that depends also on the monomer volume fraction, phi, chieff(phi,T). Such chieff(phi,T) can arise from two state-models, proposed for polyetheleneoxide (PEO) and other neutral water-soluble polymers. The predicted phi dependence of chibar=chieff-(1-phi)\partial \chieff/\partial phi, obtainable from colligative properties, differs qualitatively between the various models: (i) The model of Karlstrom (J. Phys. Chem. 1985, 89, 4962) yields \partial chibar/\partial phi > 0 while the model of Matsuyama and Tanaka (Phys. Rev. Lett. 1990, 65, 341) and of Bekiranov et al (Phys. Rev. E 1997, 55, 577) allows for \partial chibar/\partial phi <0 (ii) chibar(phi) as calculated from the Karlstrom model, utilizing the parameters used to fit the phase diagram of PEO, agrees semiquantitatively with the experimental values. On the other hand, chibar(phi) similarly calculated from the model of Bekiranov et al. differs qualitatively from the measured results. Altogether, chibar(phi) provides useful measure for the performance of a model.Comment: 8 pages, 5 figures, Macromolecules, in pres