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Proceedings of the biosimilars workshop at the International Symposium on Oncology Pharmacy Practice 2019.
The International Society of Oncology Pharmacy Practitioners organized a workshop to create learning opportunities on biosimilars in pharmacy practice on 10 October 2019. The topics that were covered included (i) the development and testing of biosimilars, (ii) the challenges of bringing biosimilars to market, and (iii) real-world data on patient safety and perceptions during biosimilar implementation. The development of biosimilars can take up to eight years and the extensiveness of the process depends on several factors, such as the complexity of the production process and regulatory requirements. Compared to generic products of small-molecule drugs, there is a higher barrier to market entry for biosimilars, explaining the small number of biosimilars in the market. Appraisal of biosimilars for inclusion in hospital formularies is also different from the review process of originator biologics, where the former is usually institution-led and has fewer restrictions on use. When several biosimilar products are available, factors that should be considered besides cost are licensed indications, supply chain confidence, clinical data, and product attributes. Real-world data have shown that biosimilars are well-tolerated and have safety data that are comparable to that of the originator product. Oncology pharmacists from the United Kingdom, Kenya, and Canada also presented their respective experiences with biosimilar use. Different countries at varying stages of biosimilar implementation faced distinct challenges. Nevertheless, resources to assist biosimilar implementation can potentially be shared between different regions. International Society of Oncology Pharmacy Practitioners is well-positioned to foster professional cooperation at an international level to drive biosimilar implementation
Speech Recognition Technology: Improving Speed and Accuracy of Emergency Medical Services Documentation to Protect Patients
Because hospital errors, such as mistakes in documentation, cause one sixth of the deaths each year in the United States, the accuracy of health records in the emergency medical services (EMS) must be improved. One possible solution is to incorporate speech recognition (SR) software into current tools used by EMS first responders. The purpose of this research was to determine if SR software could increase the efficiency and accuracy of EMS documentation to improve the safety for patients of EMS. An initial review of the literature on the performance of current SR software demonstrated that this software was not 99% accurate and therefore, errors in the medical documentation produced by the software could harm patients. The literature review also identified weaknesses of SR software that could be overcome so that the software would be accurate enough for use in EMS settings. These weaknesses included the inability to differentiate between similar phrases and the inability to filter out background noise. To find a solution, an analysis of natural language processing algorithms showed that the bag-of-words post processing algorithm has the ability to differentiate between similar phrases. This algorithm is the best suited for SR applications because it is simple yet effective compared to machine learning algorithms that required a large amount of training data. The findings suggested that if these weaknesses of current SR software are solved, then the software would potentially increase the efficiency and accuracy of EMS documentation. Further studies should integrate the bag-of-words post processing method into SR software and field test its accuracy in EMS settings.https://scholarscompass.vcu.edu/uresposters/1273/thumbnail.jp
Preliminary list of bryophytes of Heishiding Nature Reserve, Guangdong Province, China
Thirty-seven species of hepatics and 66 species of mosses are reported from Heishiding Nature Reserve, including eight taxa new to China and one species new to mainland China. The new taxa for China are Ectropothecium aneitense Broth., Gammiella tonkinensis (Broth. & Par.) Tan, G. touwii Tan, Hypnum fauriei Card., Papillidiopsis complanata (Dix.) Buck & Tan, Syrrhopodon prolifer Schwaegr. var. papillosum (C.Müll.) Reese, Trichosteleum pseudo-mammosum Fleisch., and Trichostomum crispulum Bruch; and the species new to mainland China is Isocladiella surcularis (Dix.) Tan & Mohamed. The phytogeography of the area and the bryophytes are discussed
The Tan and Cardinal Special Edition 1976
In September 1917, the first edition of The Tan and Cardinal went on sale. The T&C (as it was known) was traditionally published on Thursday, and ran from the start of the school year in September, through the end in June
The Tan and Cardinal May 25, 1973
In September 1917, the first edition of The Tan and Cardinal went on sale. The T&C (as it was known) was traditionally published on Thursday, and ran from the start of the school year in September, through the end in June
Identification of new sources of resistance to tan spot of wheat
Non-Peer ReviewedTan spot, caused by Pyrenophora tritici-repentis, is a major foliar disease of wheat in
western Canada. Isolates of P. tritici-repentis are presently classified into 11 races based
on their virulence on a set of wheat differential cultivars. In western Canada only 5 of
these races have been identified. More than 1000 accessions of wheat including
synthetics and wild relatives were evaluated for resistance against all the virulent races of
P. tritici-repentis that are prevalent in western Canada. Disease screening was done
under controlled environmental conditions at the seedling stage. High level resistance to
P. tritici-repentis was observed in some accessions of Triticum monococum, T. turgidum,
T. dicoccum, T. dicoccoides, T. timopheevii, and T. aestivum including synthetic wheat.
These accessions also showed good resistance to the leaf spot disease stagnospora
nodorum blotch. They will be studied further to determine the genetic basis of resistance
and to transfer their resistance to adapted wheat and durum cultivars
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