A simple and efficient one pot synthesis of 2,4 dioxopyrimidine carbonitrile and 4-oxo-2-thioxopyrimidine carbonitrile derivatives using ammonium chloride under solvent free conditions

997-999Various substituted 4-oxo-2-thioxopyrimidine and 2,4-dioxo-pyrimidine derivatives have been synthesized by ternary condensation of ethyl cyanoacetate, aldehyde and thiourea/urea by using ammonium chloride. Structures of all the products are supported by their spectral data