How Sport and Art could be Effective in the Fields of Social, Cognitive and Emotional Learning?

AbstractMission of education in each country is to strengthen human attitude, promoting its philosophy and developing the individual's ability to live healthy and productive in the society. One of the features in the modern education is special attention to psychological and physical activities that students do at school. Development and enrichment of sports and arts activities, according to fairly centralized approach in curriculum planning and lack of sufficient attention to developing learner's social, emotional and cognitive skills in the teaching-learning process is needed. Thinking in this area makes obvious the emergence of new policy making in the school formal programs

Improvement in Sp1 binding site prediction by combining MNN data from different modifications.

<p>ROC curves for a number of different methods for predicting bound locations. Results of predictions made by combining all 21 modifications (green line); 8 modifications (black line) and integrating H2A.Z and H3K4me3 data (blue line). Comparing this figure with <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0089226#pone-0089226-g001" target="_blank">Figure 1</a> shows that applying the LRCs to the data of single modifications perform better than those LRCs trained with the combination of histone modifications. This may be due to the fact that the predictive ability for distinguishing true target regions is redundantly encoded among histone marks.</p

ROC curves for predicting the binding regions of Sp1using the MNN feature.

<p>ROC curves for 21 LRCs trained on individual histone modifications for prediction of Sp1 binding regions, using the MNN feature. The LRCs corresponding to each histone modification were trained on Chromosome 1 and tested on Chromosome 2 to 22 and two sex chromosomes. The LRCs assign a score to each interval. Predictions of binding regions are based on these scores. These curves show that the MNN feature is predictive of binding regions even when no PWM score is used. The x-axis is the false positive rate and the y-axis is the true positive rate. Shown are the curves of the most predictive modifications. ROC curves for the rest 13 modifications can be found in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0089226#pone.0089226.s001" target="_blank">Figure S1</a>.</p

Histone modification types.

<p>Each modification is clustered into active, repressive or moderate type based on their association with active or repressed genes. Moderate marks show a dual tendency toward active and repressed genes.</p

Coexistence of periorbital lichen planus pigmentosus and pemphigus vulgaris: Report of an unusual case and a rare association

Abstract Lichen planus pigmentosus is a rare variant of lichen planus with different patterns and manifestations. The coexistence of LPP and PV suggests that there might be a relationship between these two conditions in terms of immunologic mechanisms

Distributions of nucleosome positions around Sp1 binding sites.

<p>Distributions of the central positions of nucleosomes for the top 8 marks and 3 repressive marks around Sp1 binding sites on the genome. The x-axis shows genomic positions with respect to central position of Sp1 binding sites (from −1015bp to +1015bp). The positions of nucleosomes are defined as the positions from −15 bp to 15 bp with respect to the center of the nucleosome. Active marks are highly enriched around binding sites and show a bimodal distribution around these sites. A nucleosome free region with respect to central position of binding sites is also observable in all top marks.</p

AUC values corresponding to different histone modifications for predicting the binding regions of Sp1 based on the MNN feature.

<p>Results are shown for predicting the binding sites of Sp1 in CD4+T cells using the MNN feature. The height of each bar corresponds to the Area under the ROC curves. Certain modifications are more predictive for true binding regions. Comparing the results with using the PWM alone (Figure3) clearly shows that the MNN feature, especially for certain modifications, can be used as an informative feature for TFBSs prediction.</p