膵癌術後予防肝動注におけるリザーバー留置術の検討 : 従来法とcoaxialシステムの比較

PURPOSE: Previous reports have shown the effectiveness of adjuvant hepatic arterial infusion chemotherapy (HAIC) in pancreatic cancer. However, percutaneous catheter placement is technically difficult after pancreatic surgery. The purpose of this study was to evaluate the feasibility and outcome of HAIC using a coaxial technique compared with conventional technique for postoperative pancreatic cancer. MATERIALS AND METHODS: 93 consecutive patients who received percutaneous catheter-port system placement after pancreatectomy were enrolled. In 58 patients from March 2006 to August 2010 (Group A), a conventional technique with a 5-Fr indwelling catheter was used and in 35 patients from September 2010 to September 2012 (Group B), a coaxial technique with a 2.7-Fr coaxial catheter was used. RESULTS: The overall technical success rates were 97.1 % in Group B and 86.2 % in Group A. In cases with arterial tortuousness and stenosis, the success rate was significantly higher in Group B (91.7 vs. 53.8 %; P = 0.046). Fluoroscopic and total procedure times were significantly shorter in Group B: 14.7 versus 26.7 min (P = 0.001) and 64.8 versus 80.7 min (P = 0.0051), respectively. No differences were seen in the complication rate. The 1 year liver metastasis rates were 9.9 % using the conventional system and 9.1 % using the coaxial system (P = 0.678). The overall median survival time was 44 months. There was no difference in the survival period between two systems (P = 0.312). CONCLUSIONS: The coaxial technique is useful for catheter placement after pancreatectomy, achieving a high success rate and reducing fluoroscopic and procedure times, while maintaining the safety and efficacy for adjuvant HAIC in pancreatic cancer.博士（医学）・乙第1380号・平成28年7月8日© Springer Science+Business Media New York and the Cardiovascular and Interventional Radiological Society of Europe (CIRSE) 2016The final publication is available at Springer via http://dx.doi.org/10.1007/s00270-016-1292-

Clinical Effect of Infusion Therapy in Combination with Local Antimycotic Drugs on Acute Pseudomembraneous Candidiasis Induced by Removable Dentures

Denture stomatitis is often observed in the denture-bearing mucosa. Candida albicans and related species are now believed to play a major role as a pathogenic factor in denture stomatitis. If systemic predisposing factors are present, denture stomatitis will sometimes develop into acute pseudomembraneous candidiasis. In acute pseudomembraneous candidiasis, the patients cannot take foods, and dehydration often occurs. This vicious cycle is the most important cause of increase in the growth of Candida species. Therefore, in order to improve the patient's physical condition, infusion therapy will be the first choice of treatment. The purpose of this study was to investigate the clinical effect of infusion therapy in combination with local antimycotic drugs on this type of candidiasis. We observed 4 cases of acute pseudomembraneous candidiasis induced by removable dentures and tried to treat these patients with infusion therapy (5% dextrose in lactatedRinger's solution) and local antimycotic drugs (Nystatin ointment or 1 % Miconazole nitrate cream). The acute inflammatory symptoms were significantly decreased by this therapy. The result of this study indicated that infusion therapy in combination with local antimycotic drugs was clinicaly effective on acute pseudomembraneous candidiasis induced by Candida-induced denture stomatitis

Development of a Visualization Method for Motion-characteristic Distribution of Japanese Folk Dances - A Case Study of the Bon Odori Dance

This study proposes a method to systematically visualize the motion-characteristic distribution of Japanese folk dances passed down in a certain area. This is accomplished by adopting an approach that involves analyzing motion-capture data collected from the dances. The visualization process in the proposed method consists of three stages. The first stage is the modeling of the relationship among motion-capture data, folk dances, and the settlements in which folk dances have been passed down. This relationship is modeled as a hierarchical-structure model. The second stage is the extraction of motion characteristics from motion-capture data streams. The motion characteristics of each data stream are summarized as a fourteen-dimensional feature vector. The third stage is the visualization of the motion-characteristic distribution of the dances investigated. Each of the dances is mapped on a two-dimensional scatter plot in accordance with the feature quantities obtained in the second stage. Information on the hierarchical-structure model constructed in the first stage is also displayed. The analysis results for the distribution of Bon Odori dances showed that the proposed method could have almost completely visualized the motion-characteristic distribution of sample folk dances, while also demonstrating consistency with the knowledge of the dances acquired in the previous studies

Adjuvant Hepatic Arterial Infusion Chemotherapy After Resection for Pancreatic Cancer Using Coaxial Catheter-Port System Compared with Conventional System.

PURPOSE: Previous reports have shown the effectiveness of adjuvant hepatic arterial infusion chemotherapy (HAIC) in pancreatic cancer. However, percutaneous catheter placement is technically difficult after pancreatic surgery. The purpose of this study was to evaluate the feasibility and outcome of HAIC using a coaxial technique compared with conventional technique for postoperative pancreatic cancer. MATERIALS AND METHODS: 93 consecutive patients who received percutaneous catheter-port system placement after pancreatectomy were enrolled. In 58 patients from March 2006 to August 2010 (Group A), a conventional technique with a 5-Fr indwelling catheter was used and in 35 patients from September 2010 to September 2012 (Group B), a coaxial technique with a 2.7-Fr coaxial catheter was used. RESULTS: The overall technical success rates were 97.1 % in Group B and 86.2 % in Group A. In cases with arterial tortuousness and stenosis, the success rate was significantly higher in Group B (91.7 vs. 53.8 %; P = 0.046). Fluoroscopic and total procedure times were significantly shorter in Group B: 14.7 versus 26.7 min (P = 0.001) and 64.8 versus 80.7 min (P = 0.0051), respectively. No differences were seen in the complication rate. The 1 year liver metastasis rates were 9.9 % using the conventional system and 9.1 % using the coaxial system (P = 0.678). The overall median survival time was 44 months. There was no difference in the survival period between two systems (P = 0.312). CONCLUSIONS: The coaxial technique is useful for catheter placement after pancreatectomy, achieving a high success rate and reducing fluoroscopic and procedure times, while maintaining the safety and efficacy for adjuvant HAIC in pancreatic cancer.博士（医学）・乙第1380号・平成28年7月8日© Springer Science+Business Media New York and the Cardiovascular and Interventional Radiological Society of Europe (CIRSE) 2016The final publication is available at Springer via http://dx.doi.org/10.1007/s00270-016-1292-7identifier:Cardiovascular and interventional radiology Vol. 39 No.6 p.831-839 (2016 Jun)identifier:01741551identifier:http://ginmu.naramed-u.ac.jp/dspace/handle/10564/3259identifier:Cardiovascular and interventional radiology, 39(6): 831-83

A Motion Data Segmentation Method Using Self-Prganizing Map for Making a Buyo-fu Automatically

We have proposed a human motion description method using a Buyo-fu(dancing note) in order to reuse motion data captured by a motion capturing system. The Buyo-fu can give us an efficient support for archiving and learning traditional dances. The motion of a dance can be segmented into some motion primitives, and we define a Buyo-fu as a code that is assigned to each motion primitive. Since we have been making a Buyo-fu manually so far, there exists a problem that making a Buyo-fu requires not only much cost but also an expert knowledge about the dance.In this report, we propose a method to segment human motion data into some motion primitives in order to make a Buyo-fu automatically. We consider that human motion data consist of a series of human postures and that a motion primitive is a segment which consists of a series of human postures having similar characteristics to each other. According to these considerations, we discussed a method to segment human motion data into motion primitives by clustering postures. As a result, we have developed a clustering method for segmentation by using a modified self-organizing map(SOM) that can treat a time-series of data.We made an experiment on a Japanese folk dance whose name is “Nishimonai Ganke”, and we confirmed that our proposed method could be used to make a Buyo-fu automatically

秋田県の民俗芸能研究におけるモーションキャプチャデータの活用

application/pdf秋田県には数多くの民俗芸能が存在し，それらのうちのいくつかは国や地方自治体によって重要無形民俗文化財に指定されている．我々の研究グループでは，モーションキャプチャシステムを用いて取得した身体動作データを解析することによって，それぞれの民俗芸能において演じられる民俗舞踊の特徴を抽出し，種々の検討を行ってきた．ここでは，それらの試みを紹介し，今後の展望を考察する．In Akita Prefecture, Japan, a lot of folk performing arts have been passed down, and some of them are designated as important intangible folk cultural properties by the national government or the local public entities. Our research group has made efforts to carry out studies to extract the characteristics of the dances performed in the folk performing arts of Akita Prefecture, through the analysis of motion capture data. In this report, we introduce some representative examples and consider the prospects for the future