チェーンストア型サービス業における価値共創マネジメント ―QBハウスによる事業モデルの転換―

　チェーンストア型サービス業では、従来価値共創の実現が難しいと位置づけられてきた。しかしこの領域においても価値共創が実現し、かつ価値共創によりチェーンストア型サービス業の構造的な課題であるコモディティ化と従業員の疲弊や離職の増加を解決できる可能性があることを、QBハウスの事例研究を通して論じた

Ultrawideband Systems and Networks: Beyond C + L-Band

In the evolution of optical networks, enhancement of spectral efficiency (SE) enhancement has been the most cost-efficient and thus the main driver for capacity enhancementincrease for decades. As a result, the development of optical transport systems has been focused on the C -and L -bands, where silica optical fiber exhibits the lowest attenuation, and erbium-doped fiber amplifiers provide an efficient solution forto compensatinge for the optical loss. With a gradual maturity in the SE growth, however, the extension of the optical bandwidth beyond the C + L -band is expected to play a significant role in the future capacity upgrades of optical networks and, thus, attracting increasing research interests. In this article, we discuss the merits and challenges of ultrawideband optical transport systems and networks beyond conventional bands

MicroRNA Profile Predicts Recurrence after Resection in Patients with Hepatocellular Carcinoma within the Milan Criteria

Objective: Hepatocellular carcinoma (HCC) is difficult to manage due to the high frequency of post-surgical recurrence. Early detection of the HCC recurrence after liver resection is important in making further therapeutic options, such as salvage liver transplantation. In this study, we utilized microRNA expression profiling to assess the risk of HCC recurrence after liver resection. Methods: We examined microRNA expression profiling in paired tumor and non-tumor liver tissues from 73 HCC patients who satisfied the Milan Criteria. We constructed prediction models of recurrence-free survival using the Cox proportional hazard model and principal component analysis. The prediction efficiency was assessed by the leave-one-out crossvalidation method, and the time-averaged area under the ROC curve (ta-AUROC). Results: The univariate Cox analysis identified 13 and 56 recurrence-related microRNAs in the tumor and non-tumor tissues, such as miR-96. The number of recurrence-related microRNAs was significantly larger in the non-tumor-derived microRNAs (N-miRs) than in the tumor-derived microRNAs (T-miRs, P, 0.0001). The best ta-AUROC using the whole dataset, T-miRs, NmiRs, and clinicopathological dataset were 0.8281, 0.7530, 0.7152, and 0.6835, respectively. The recurrence-free survival curve of the low-risk group stratified by the best model was significantly better than that of the high-risk group (Log-rank: P = 0.00029). The T-miRs tend to predict early recurrence better than late recurrence, whereas N-miRs tend to predict late recurrence better (P, 0.0001). This finding supports the concept of early recurrence by the dissemination of primary tumor cells and multicentric late recurrence by the ‘field effect’. Conclusion: microRNA profiling can predict HCC recurrence in Milan criteria cases

Initial Tap Setup of Constant Modulus Algorithm for Polarization De-multiplexing in Optical Coherent Receivers

Abstract: We demonstrate a modified constant modulus algorithm (CMA) for polarization de-multiplexing and equalization. By designing the initial tap values for CMA, degeneration of the two polarization tributaries can be avoided. ©2009 Optical Society of America OCIS codes: (060.1660) Coherent communications; (060.2360) Fiber optics links and subsystems 1

Single-wavelength, single-photodiode per polarization 276 Gb/s PDM 8-QAM over 100 km of SSMF

We demonstrate heterodyne detection of 46 Gbaud polarization-multiplexed QAM signaling using a transmitter based on a conventional dual-polarization I/Q modulator and a receiver consisting of two single-photodiodes without a local oscillator

Single-wavelength, single-photodiode per polarization 276 Gb/s PDM 8-QAM over 100 km of SSMF

\u3cp\u3eWe demonstrate heterodyne detection of 46 Gbaud polarization-multiplexed QAM signaling using a transmitter based on a conventional dual-polarization I/Q modulator and a receiver consisting of two single-photodiodes without a local oscillator.\u3c/p\u3