269 research outputs found
Mechanical Property Evaluation of Electrodeposited Nanocrystalline Metals by Micro-testing
Electrodeposition is a very important technology in the fabrication of micro-components for micro-electro-mechanical systems (MEMS) or integrated circuits. Evaluations of the materials used in these devices as 3D components should be conducted using micro-sized specimens due to the sample size effect on the practical use of the components. Nanocrystalline metals could be deposited using an electrodeposition method with supercritical CO2 emulsion. Our experiment on the micro-specimens provides information on micro-mechanical testing of electrodeposited metals including the effect of sample size, grain size, and anisotropic structures on mechanical properties. In this chapter, recent studies on crystal growth in electrodeposition of metals and its evaluation using micron-sized testing will be presented
Software Defined Media: Virtualization of Audio-Visual Services
Internet-native audio-visual services are witnessing rapid development. Among
these services, object-based audio-visual services are gaining importance. In
2014, we established the Software Defined Media (SDM) consortium to target new
research areas and markets involving object-based digital media and
Internet-by-design audio-visual environments. In this paper, we introduce the
SDM architecture that virtualizes networked audio-visual services along with
the development of smart buildings and smart cities using Internet of Things
(IoT) devices and smart building facilities. Moreover, we design the SDM
architecture as a layered architecture to promote the development of innovative
applications on the basis of rapid advancements in software-defined networking
(SDN). Then, we implement a prototype system based on the architecture, present
the system at an exhibition, and provide it as an SDM API to application
developers at hackathons. Various types of applications are developed using the
API at these events. An evaluation of SDM API access shows that the prototype
SDM platform effectively provides 3D audio reproducibility and interactiveness
for SDM applications.Comment: IEEE International Conference on Communications (ICC2017), Paris,
France, 21-25 May 201
Detection of EGFR T790M Mutation in Pericardial Effusion from a Non-Small Cell Lung Cancer Patient with Erlotinib Therapy
We report the case of a Japanese male with epidermal growth factor receptor tyrosine kinase inhibitor (EGFR-TKI)-sensitive lung adenocarcinoma, who had an EGFR mutation and presented in the emergency department with acute cardiac tamponade as the recurrence during EGFR-TKI therapy. We could detect a second mutation, T790M in exon 20 in the pericardial effusion. This is the first report to detect the resistant mutation T790M in pericardial effusion. We suggest that the pericardial effusion may therefore be useful as surrogate tissue for detecting EGFR mutation
Comparative Analysis of Epidermal Growth Factor Receptor Mutations and Gene Amplification as Predictors of Gefitinib Efficacy in Japanese Patients With Nonsmall Cell Lung Cancer
取得学位 : 博士(医学), 学位授与番号 : 医博甲第1895号 , 学位授与年月日 : 平成19年9月28日, 学位授与大学 : 金沢大学, 主査教授 : 金子 周一, 副査教授 : 矢野 聖二 , 渡邊
Transgenic mice overexpressing SREBP-1a under the control of the PEPCK promoter exhibit insulin resistance, but not diabetes
AbstractSterol regulatory element-binding protein-1 (SREBP-1) is a transcription factor which regulates genes involved in the synthesis of fatty acids and triglycerides. The overexpression of nuclear SREBP-1a in transgenic mice under the control of the PEPCK promoter (TgSREBP-1a) caused a massively enlarged fatty liver and disappearance of peripheral white adipose tissue. In the current study, we estimated the impact of this lipid transcription factor on plasma glucose/insulin metabolism in vivo. TgSREBP-1a exhibited mild peripheral insulin resistance as evidenced by hyperinsulinemia both at fasting and after intravenous glucose loading, and retarded glucose reduction after insulin injection due to decreased plasma leptin levels. Intriguingly, hyperinsulinemia in TgSREBP-1a mice was markedly exacerbated in a fed state and sustained after intravenous glucose loading, and paradoxically decreased after the portal injection of glucose. TgSREBP-1a mice consistently showed very small plasma glucose increases after portal glucose loading because of a large capacity for hepatic glucose uptake. These data suggested that hepatic insulin resistance emerges postprandially. In addition, pancreatic islets from TgSREBP-1a were enlarged. These data demonstrate that SREBP-1a activation in the liver has a strong impact on plasma insulin levels, implicating the potential role of SREBPs in hepatic insulin metabolism relating to insulin resistance
眼球運動を考慮したOCT断面画像の位置合わせ手法
平成20年度電気・情報関連学会中国支部第59回連合大会発表資料 ; 開催地:鳥取大学 ; 開催日:2008年10月25
OCT断面画像を用いた眼底形状の特徴量計測
平成18年度電気・情報関連学会中国支部第57回連合大会資料 岡山理科大学, 岡山 (2006 10
Registration method for OCT cross sectional images considering eye movement
第10回IEEE広島支部学生シンポジウム(HISS), ポスター ; 開催場所:広島 ; 開催日:2008年11月21-23
IOLmodeling and light imulation for glare source analysis
MIRU2007 第10回 画像の認識・理解シンポジウム ポスター資料 ; 開催日時:2007年7月30日~8月1
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