Application of Imaging Technology to Humans

Recent development of imaging technology has been remarkable and has given great impact to life science research. Moreover, attempts to apply this novel technique to humans and practice it in clinical medicine have also started. Especially, some articles report the utility of imaging living tissues that do not require any labeling in recent years. This “non-labeling imaging” technique has a great potential in human application and clinical medicine practice. In this review, we describe the application of imaging technology to humans, mainly focusing on the diagnosis of cancer by non-labeling imaging with multiphoton excitation microscopy.The version of record of this article, first published in Make Life Visible, is available online at Publisher’s website: https://doi.org/https://doi.org/10.1007/978-981-13-7908-6_2

COMPUTER-BASED LEARNING USING CAPTURED TENNIS SERVE MOTION

INTRODUCTION: Motion analysis techniques have revealed kinetic and kinematic aspects of the sport motions, however, more intuitive resources, e.g. visual feedback, would be recommended to the sport practitioners. Féry & Crognier (2001) showed that essential anticipatory information is contained in the opponent’s stroke motion whatever the tactical significance of the situation. Fukuhara et al (2005) proposed that computer graphics animation have possibilities to be utilized in the sport visual training. This study aimed to explore the effect of computer-based visual learning in tennis by testing the judgment performance of novice player who viewed a captured tennis serve animation

Temporal variation in the depth of the magma surface at Aso volcano in 2014–2015

Monitoring the depth of the magma surface at open-vent volcanoes can be a practical tool to infer temporal variations in the magma supply during an eruption. We focus on the magmatic eruption of Aso volcano in 2014–2015 to estimate the temporal change in the depth of the magma surface, and show that this needs to be coupled with an understanding of the shallow conduit geometry if it is to be done in a representative manner. The eruption lasted 5 months from November 2014 and ending with a crater floor collapse in May 2015. During the eruption, we recorded seismo-acoustic waveforms related to frequent Strombolian explosions. The infrasound signals show several distinct peak frequencies derived from acoustic resonance inside the vent. We estimate the depth of the magma surface using the time delay of seismo-acoustic signals and the peak frequency of infrasound signals. In addition, the temporal variation in the shape of the conduit is constrained by the overtone frequency of the acoustic resonance. From the beginning of the eruption to early-January 2015, the magma surface was located at a depth of ∼ 200 m, and the conduit was a cylindrical pipe. Later, between January and February, the magma surface rose to ∼ 120 m, and the shape of the conduit changed to a conical frustum flaring inside. This finding indicates that the magma was injected into the shallow conduit and that it heated and weakened the conduit wall near the magma surface. Before the cessation of the magmatic eruption, the magma surface dropped by approximately 70 m. This magma drainage and, primarily, the instability of the conduit shape caused the crater floor to collapse. We show the possibility of tracking and assessing the depth of the magma surface and the shallow conduit geometry even with limited seismo-acoustic observations

Capgermacrene C, a New Sesquiterpenoid from a Bornean Soft Coral, Capnella sp.

A new bicyclogermacrene, capgermacrene C (1), along with a known compound, 1,4-peroxy-5-muurolene (2), were isolated from a population of Bornean soft coral Capnella sp. The structures of these metabolites were determined by extensive spectroscopic analysis, including NMR, and HRESIMS. Both compounds were subjected to antibacterial activity tests against antibiotic resistant clinical bacteria, but produced only negligible inhibition

Autonomous Navigation, Guidance and Control of Small Electric Helicopter

In this study, we design an autonomous navigation, guidance and control system for a small electric helicopter. Only small, light-weight, and inaccurate sensors can be used for the control of small helicopters because of the payload limitation. To overcome the problem of inaccurate sensors, a composite navigation system is designed. The designed navigation system enables us to precisely obtain the position and velocity of the helicopter. A guidance and control system is designed for stabilizing the helicopter at an arbitrary point in three-dimensional space. In particular, a novel and simple guidance system is designed using the combination of optimal control theory and quaternion kinematics. The designs of the study are validated experimentally, and the experimental results verify the efficiency of our navigation, guidance and control system for a small electric helicopter.ArticleINTERNATIONAL JOURNAL OF ADVANCED ROBOTIC SYSTEMS. 10:54 (2013)journal articl

12Epi -9deacetoxyxenicin, new cytotoxic diterpenoid from a Bornean soft coral Xenia sp

One new compound, 12-epi-9-deacetoxyxenicin (1) along with a hydroperoxide product, 12-epi-9-deacetoxy-8-hydroperoxyxenicin (2) and two known sesquiterpenoids (3–4) were isolated from a population of Bornean soft coral Xenia sp. The structures of these secondary metabolites were elucidated based on their spectroscopic data. Compounds 1 and 2 showed cytotoxic activity against ATL cell line, S1T. In addition, compound 3 exhibited hyphal inhibition of Lagenidium thermophilum