MIELOLIPOMA ESPLÊNICO FELINO

Myelolipomas are benign neoplasms of adipose cells that contain hematopoietic elements, considered infrequent and difficult to diagnose. The following paper reports a case of splenic myelolipoma diagnosed in a feline in the southern region of Rio Grande do Sul. The patient was referred for care at a veterinary clinic but died. Macroscopically, a nodule measuring 2.0 cm in diameter was observed in the spleen, with a cut surface that was lighter in color than the organ and soft in consistency. Histologically, there was proliferation of mature and well-differentiated adipose tissue, with cells of round to oval shapes, with small and peripheral nuclei, together with a large number of hematopoietic cells consisting of megakaryocytes, mature erythrocytes, in addition to macrophages, lymphocytes and plasma cells. These cellular components were also visualized in other organs, namely the pancreas, kidneys, liver and heart, characterizing the neoplasm. There are few descriptions of splenic myelolipoma in felines in the literature. In Brazil there is a description of this neoplasm in the spleen only in canines. Despite being a benign neoplasm, it should be considered in the differential diagnosis of pathologies that affect the lymphoid system.Os mielolipomas são neoplasias benignas de células adiposas que contêm elementos hematopoiéticos, consideradas infrequentes e de difícil diagnóstico. O seguinte trabalho relata um caso de mielolipoma esplênico diagnosticado em um felino na região Sul do Rio Grande do Sul. A paciente foi encaminhada para atendimento em uma clínica veterinária, porém ocorreu o óbito. Na necropsia foi observado um nódulo no baço, medindo 2,0cm de diâmetro, com superfície de corte de coloração mais clara que o órgão e de consistência macia. Histologicamente havia proliferação de tecido adiposo maduro e bem diferenciado, com células de formatos redondos a ovais, com núcleos pequenos e periféricos junto à grande quantidade de células hematopoiéticas constituídas por megacariócitos, eritrócitos maduros, além de macrófagos, linfócitos e plasmócitos. Estes componentes celulares foram visualizados, também, em outros órgãos, sendo eles: o pâncreas, rins, fígado e coração, caracterizando a neoplasia. Há poucas descrições de mielolipoma esplênico em felinos na literatura. No Brasil há descrição desta neoplasia no baço somente em caninos. Apesar de se tratar de uma neoplasia de caráter benigno, ela deve ser considerada no diagnóstico diferencial de patologias que acometem o sistema linfóide

Feline rabies caused by a viral variant of insectivorous bat

ABSTRACT: Rabies is an invariably fatal infectious-contagious viral disease caused by viruses in the genus Lyssavirus, which affects the central nervous system of domestic and wild mammals. This study draws attention to the importance of insectivorous bats and domestic cats in the epidemiology of rabies. For this, two cases of rabies registered in domestic cats in the southeast region of Rio Grande do Sul were analyzed. Diagnoses were based on histological alterations and positive staining for the virus in direct immunofluorescence with confirmation by biological test, immunohistochemical evaluation and identification of the rabies virus variant by polymerase chain reaction. In Brazil, a change in the epidemiological profile of rabies has been observed, in which bats play a major role in the current chain of transmission of the disease. It is noteworthy, that the antigenic viral variant AgV-4, typical of the insectivorous bat Tadarida brasiliensis, was identified in the domestic cats affected in this study