Extraocular Muscle Imbalance and Outcomes of Scleral Buckling Surgery for Primary Rhegmatogenous Retinal Detachment

Objective: The objective was to study the muscle imbalance, restrictive motility in unlike gazes and the outcomes of the scleral buckling surgery for rhegmatogenous retinal detachment. Study design: Prospective follow-up study Settings and duration: The study was conducted at Al-Shifa Trust Eye Hospital Rawalpindi from Aug 2015 to Jan 2016. Methodology: The patients were checked prior to surgery and two follow up visits were done afterwards. Thorough history was taken along with full orthoptic assessment and ocular motility in all four main gazes including elevation, depression, adduction and abduction. Vision, type and position of explants, site of detachment, and risk factors of detachment were also observed. Results: A total of 48 eyes of 46 patients were taken. Mean age of the study participants was 37.16±20.37 years. Horizontal, vertical and combined deviations were observed in study population. Exo deviation was most common deviation among patients. Most reported risk factors of retinal detachment included trauma, pseudophakia, aphakia and myopia. Motility limitations of all four gazes was observed and it was found out that after buckling the squint and restriction is been increased up till two months. Conclusion: Ocular restriction among the patients was observed over a period of 2 months and it depicted that encircling with sclera buckling elicited an increase in restrictive ocular motility from pre-operative to 1 week and 2 months after surgery

Prospects of microalgal biodiesel production in Pakistan – a review

Biodiesel is an alternative, renewable, biodegradable and environmentally friendly fuel for transportation, with properties like petroleum-derived diesel, and can be used directly in a compression ignition engine without any modifications. The world's fossil fuel and crude oil reserves are going to dry up in the next few decades, but, contrariwise, an attractive, high quality, readily available and economically extractable oil from microalgae is a substitute feedstock to produce alternative biodiesel fuel for the transportation sector in the future. Microalgae have a higher biomass productivity (tons/hectare/year) and lipid yield (kg/kg of algal biomass) as compared to vegetable oil crops. To overcome the problem of energy deficiency in developing countries, like Pakistan, and boost their economic growth, alternative fuels are proving very important for environment-friendly and sustainable development, especially in the last few decades. Different research studies on microalgae cultivation, characterization of microalgae oil (lipids), and evaluations of its socio-economic feasibility to produce renewable biodiesel have been conducted in the past in Pakistan for its future prospects. This review paper includes the overall summary and compilation of the microalgae research conducted in Pakistan on biodiesel production and includes the algal biodiesel production cost analysis. The studies showed promising results for harnessing microalgae and using its lipids to produce biodiesel with favourable properties that were comparable to the conventional diesel in Pakistan. The information related to the microalgae research will help stakeholders and governmental organisations working in the renewable energy sector to consider its cultivation on a large scale, using waste water as a feedstock to produce biodiesel to meet the target set by the Government of Pakistan of using 10% blended biodiesel by the year 2025 in Pakistan

To determine the frequency of Group B Streptococcal colonization of vagina in women at 35-37 week pregnancy

BACKGROUND: Group B streptococci (GBS) is the usually present in vaginal canal in micro-flora, which usually do not exhibit any symptoms. Instead, in pregnancy, there are certain situations in GBS colonization in vagina, which may lead to several complications. OBJECTIVE: To determine the frequency of Group B Streptococcal colonization of vagina in women at 35-37 week pregnancy. STUDY DESIGN: Cross sectional survey SETTING: Antenatal clinic, Shalamar Hospital Lahore STUDY DURATION: 6 month i.e. From: 05-09-2014 to 06-03-2015 SUBJECTS & METHODS: 350 Booked Patients attending antenatal clinic at Shalamar hospital at 35-37 weeks of pregnancy for routine antenatal checkup were included. Lower vaginal swabs were taken without speculum using sterilized disposable cotton swab and transported to Amies Agar jell and transported to microbiology lab within 24 hours. Laboratory report was collected and reviewed by researcher regarding positive or negative culture for GBS. Patients with positive GBS culture were given intrapartum antibiotics. RESULTS: In our study, out of 350 cases, with the mean age of 26.92+4.84 years. Frequency of GBS colonization of vagina in women at 35-37 week pregnancy was recorded in 12.29% while remaining 87.71% had no findings of the morbidity. CONCLUSION: It was concluded that the frequency of GBS colonization of vagina in women at 35-37 week pregnancy is not very higher and in accordance with other regions of our country, but routine screening may further decline its incidence. KEYWORDS: Pregnancy, last trimester, Group B Streptococcal colonization of vagin

To determine the frequency of Group B Streptococcal colonization of vagina in women at 35-37 week pregnancy

BACKGROUND: Group B streptococci (GBS) is the usually present in vaginal canal in micro-flora, which usually do not exhibit any symptoms. Instead, in pregnancy, there are certain situations in GBS colonization in vagina, which may lead to several complications. OBJECTIVE: To determine the frequency of Group B Streptococcal colonization of vagina in women at 35-37 week pregnancy. STUDY DESIGN: Cross sectional survey SETTING: Antenatal clinic, Shalamar Hospital Lahore STUDY DURATION: 6 month i.e. From: 05-09-2014 to 06-03-2015 SUBJECTS & METHODS: 350 Booked Patients attending antenatal clinic at Shalamar hospital at 35-37 weeks of pregnancy for routine antenatal checkup were included. Lower vaginal swabs were taken without speculum using sterilized disposable cotton swab and transported to Amies Agar jell and transported to microbiology lab within 24 hours. Laboratory report was collected and reviewed by researcher regarding positive or negative culture for GBS. Patients with positive GBS culture were given intrapartum antibiotics. RESULTS: In our study, out of 350 cases, with the mean age of 26.92+4.84 years. Frequency of GBS colonization of vagina in women at 35-37 week pregnancy was recorded in 12.29% while remaining 87.71% had no findings of the morbidity. CONCLUSION: It was concluded that the frequency of GBS colonization of vagina in women at 35-37 week pregnancy is not very higher and in accordance with other regions of our country, but routine screening may further decline its incidence. KEYWORDS: Pregnancy, last trimester, Group B Streptococcal colonization of vagin

Epidemiological Characteristics of Poliomyelitis during the 21st century (2000-2013)

Poliovirus is the pathogenic agent of paralytic poliomyelitis that belongs to the picornaviridae family. Poliomyelitis has an extended history dating over to the Egyptian eighteenth dynasty. It was recognized as distinct disease in the late nineteenth century when the world was ravaged by large number of outbreaks and epidemics in many countries. Paralytic Polio, the rarest but the most severe form of the disease, is characterized by acute flaccid paralysis of any or rarely both of the limbs. Increasing epidemics during the late 19th and 20th centuries lead to the initiation of a worldwide global effort for polio eradication in 1988, super headed by WHO and various other organizations. The launch of Global Polio Eradication Initiative together with the introduction of two polio vaccines resulted in 99% reduction of wild poliovirus cases worldwide while the total number of polio-endemic countries dropped from 24 countries in the year 2000 to only three countries in 2012; Afghanistan, Nigeria and Pakistan. This review will focus on the general biology of poliovirus, some historic and geographic epidemiological aspects of poliomyelitis eradication during the year 2000-2012 and also on the major failing factors associated with the efficiency of the vaccines to eradicate polio in Pakistan

PERCEIVED RISK AND ONLINE PURCHASE INTENTION: THE INTERACTION EFFECT OF TRUST

This study is aimed to investigate the relationship between perceived risk and online purchase intention, as well as the moderating role of trust on the mentioned link among the university students in Pakistan. The existing literature has mainly focused on the effects of perceived risk on online purchase intention in the developed countries and oversighted the potential role of trust affecting the relationship between perceived risk and online purchase intention. This research study, thus, bridges these gaps in the literature. Purposive sampling was utilized and data was collected from 200 enrolled students through questionnaire. Results of the regression analysis demonstrated that perceived risk in online shopping is adversely related to purchase intention. Moreover, results of hierarchal regression analysis indicated that trust positively moderates the link between perceived risk and purchase intention, indicating that trust dampens the mentioned link. This study provides significant implications to online sellers to understand the underlying role of trust in reducing the perceived risk of consumers and encouraging them to engage in online shopping. This study also suggests the policy makers to devise clear, transparent and uniform policies regarding product return by consumers, product damages and exchange etc so that online businesses flourish and consumer may get benefit of ease, convenience, economy and satisfaction in the online shopping. Limitations and future research directions are provided

(2R)-2-(1,3-Dioxoisoindolin-2-yl)-3-methyl­butanoic acid

In the title compound, C13H13NO4, the dihedral angle between the nine-membered phthalimino ring system and the carb­oxy­lic acid group is 67.15 (9)°. An intra­molecular C—H⋯O close contact, which forms an S(6) ring, may help to establish the mol­ecular conformation. In the crystal, mol­ecules are linked by O—H⋯O hydrogen bonds, thereby forming C(7) chains propagating in [010]

2-(2-Oxothio­lan-3-yl)isoindoline-1,3-dione

In the title compound, C12H9NO3S, the isoindoline-1,3-dione group is almost planar, with an r.m.s. deviation of 0.020 Å, whereas the heterocyclic ring approximates to an envelope with the methyl­ene group not adjacent to the S atom in the flap position. A short intra­molecular C—H⋯O contact generates an S(6) ring motif. In the crystal structure, weak aromatic π–π stacking inter­actions occur between the centroids of the benzene rings at a distance of 3.558 (2) Å

Epidemiological Characteristics of Poliomyelitis During the 21st Century (2000-2013)

Poliovirus is the pathogenic agent of paralytic poliomyelitis that belongs to the picornaviridae family. Poliomyelitis has an extended history dating over to the Egyptian eighteenth dynasty. It was recognized as distinct disease in the late nineteenth century when the world was ravaged by large number of outbreaks and epidemics in many countries. Paralytic Polio, the rarest but the most severe form of the disease, is characterized by acute flaccid paralysis of any or rarely both of the limbs. Increasing epidemics during the late 19th and 20th centuries lead to the initiation of a worldwide global effort for polio eradication in 1988, super headed by WHO and various other organizations. The launch of Global Polio Eradication Initiative together with the introduction of two polio vaccines resulted in 99% reduction of wild poliovirus cases worldwide while the total number of polio-endemic countries dropped from 24 countries in the year 2000 to only three countries in 2012; Afghanistan, Nigeria and Pakistan. This review will focus on the general biology of poliovirus, some historic and geographic epidemiological aspects of poliomyelitis eradication during the year 2000-2012 and also on the major failing factors associated with the efficiency of the vaccines to eradicate polio in Pakistan