361 research outputs found
Partial discharges location in power transformers using piezoceramic sensors
The detection and the spatial localization of partial discharges in high-voltage electrical machines are considered as an effective method in predictive maintenance that can provide valuable information on the health of the insulation system and allow to determine accurately the location of the risky insulation elements, which in turn will avoid any premature equipment’s deterioration by scheduling preventive maintenance action. After confirming in a previous published paper the efficiency of a new generation of piezoceramics sensors (high temperature ultrasonic transducers) to detect and characterize partial discharges, we are going to investigate, in this work, a second potential of this technology to locate the partial discharge sources by relying on its ability to detect acoustic signals emitted by partial discharge sources. We will present experimental results, demonstrating the effectiveness of these sensors to locate partial discharges sources and, we will also present an algorithm for calculating the partial discharge foci, based on the acoustic wave flight time
Phonitons as a sound-based analogue of cavity quantum electrodynamics
A quantum mechanical superposition of a long-lived, localized phonon and a
matter excitation is described. We identify a realization in strained silicon:
a low-lying donor transition (P or Li) driven solely by acoustic phonons at
wavelengths where high-Q phonon cavities can be built. This phonon-matter
resonance is shown to enter the strongly coupled regime where the "vacuum" Rabi
frequency exceeds the spontaneous phonon emission into non-cavity modes, phonon
leakage from the cavity, and phonon anharmonicity and scattering. We introduce
a micropillar distributed Bragg reflector Si/Ge cavity, where Q=10^5-10^6 and
mode volumes V<=25*lambda^3 are reachable. These results indicate that single
or many-body devices based on these systems are experimentally realizable.Comment: Published PRL version. Note that the previous arXiv version has more
commentary, figures, etc. Also see http://research.tahan.com
Assessment of the Robustness of a Fixtureless Inspection Method for Nonrigid Parts Based on a Verification and Validation Approach
The increasing practical use of computer-aided inspection (CAI) methods requires assessment of their robustness in different contexts. This can be done by quantitatively comparing estimated CAI results with actual measurements. The objective is comparing the magnitude and dimensions of defects as estimated by CAI with those of the nominal defects. This assessment is referred to as setting up a validation metric. In this work, a new validation metric is proposed in the case of a fixtureless inspection method for nonrigid parts. It is based on using a nonparametric statistical hypothesis test, namely the Kolmogorov–Smirnov (K–S) test. This metric is applied to an automatic fixtureless CAI method for nonrigid parts developed by our team. This fixtureless CAI method is based on calculating and filtering sample points that are used in a finite element nonrigid registration (FENR). Robustness of our CAI method is validated for the assessment of maximum amplitude, area, and distance distribution of defects. Typical parts from the aerospace industry are used for this validation and various levels of synthetic measurement noise are added to the scanned point cloud of these parts to assess the effect of noise on inspection results
A cross-reactive antibody protects against Ross River virus musculoskeletal disease despite rapid neutralization escape in mice
Arthritogenic alphaviruses cause debilitating musculoskeletal disease and historically have circulated in distinct regions. With the global spread of chikungunya virus (CHIKV), there now is more geographic overlap, which could result in heterologous immunity affecting natural infection or vaccination. Here, we evaluated the capacity of a cross-reactive anti-CHIKV monoclonal antibody (CHK-265) to protect against disease caused by the distantly related alphavirus, Ross River virus (RRV). Although CHK-265 only moderately neutralizes RRV infection in cell culture, it limited clinical disease in mice independently of Fc effector function activity. Despite this protective phenotype, RRV escaped from CHK-265 neutralization in vivo, with resistant variants retaining pathogenic potential. Near the inoculation site, CHK-265 reduced viral burden in a type I interferon signaling-dependent manner and limited immune cell infiltration into musculoskeletal tissue. In a parallel set of experiments, purified human CHIKV immune IgG also weakly neutralized RRV, yet when transferred to mice, resulted in improved clinical outcome during RRV infection despite the emergence of resistant viruses. Overall, this study suggests that weakly cross-neutralizing antibodies can protect against heterologous alphavirus disease, even if neutralization escape occurs, through an early viral control program that tempers inflammation
Effects of Preoperative Sublingual Misoprostol on Uterine Tone during Isoflurane Anesthesia for Cesarean Section
SummaryBackground and objectivesMisoprostol would reduce the uterine bleeding after cesarean delivery without harmful effects on either mother or baby. We aimed to evaluate the effects of preoperative misoprostol on maternal blood loss, uterine tone, and the need for additional oxytocin after cesarean delivery under isoflurane anesthesia.MethodsAfter ethical approval, 366 patients scheduled for elective cesarean delivery were randomly allocated to receive either sublingual misoprostol 400μg (n=179) or placebo tablet (n=187) after intubation. Anesthesia was maintained with 0.5–0.7 MAC isoflurane with nitrous oxide. All patients received intravenous infusion of 10IU of oxytocin after placental delivery. Perioperative estimated blood loss, uterine tone, need for supplementary oxytocin, hematocrit, Apgar scores at 1 and 5 min and adverse effects were recorded.ResultsAfter induction, patients receiving sublingual misoprostol had significant less perioperative estimated blood loss (202±383.1 vs. 708±204.3mL, p<0.001), need for oxytocin (p<0.001), higher hematocrit levels (p<0.001) and uterine tone (p<0.02). The incidence of shivering was higher in the misoprostol group (p=0.04). There were no differences between the two groups as regarding Apgar scores, nausea and vomiting, gastrointestinal disturbances and pyrexia.ConclusionPreoperative administration of sublingual misoprostol 400μg is safe and effective in attenuating the maternal bleeding and uterine atony from isoflurane anesthesia for cesarean delivery
A robust and automated FE-based method for fixtureless dimensional metrology of non-rigid parts using an improved numerical inspection fixture
Dimensional inspection is an important element in the quality control of mechanical parts that have deviations from their nominal (CAD) model resulting from the manufacturing process. The focus of this research is on the profile inspection of non-rigid parts, which are broadly used in the aeronautic and automotive industries. In a free-state condition, due to residual stress and gravity loads, a non-rigid part can have a different shape compared with its assembled condition. To overcome this issue, specific inspection fixtures are usually allocated in industry to compensate for the displacement of such parts in order to simulate the use state and accomplish dimensional inspections. These dedicated fixtures, their installation and the inspection process consume a large amount of time and cost. Therefore, our principal objective has been to develop an inspection plan for eliminating the need for specialised fixtures by digitizing the displaced part's surface using a contactless (optical) measuring device and comparing the acquired point cloud with the CAD model to identify deviations. In our previous work, we developed an approach to numerically inspect the profile of a non-rigid part using a non-rigid registration method and finite element analysis. To do so, a simulated displacement was performed using an improved definition of boundary conditions for simulating unfixed parts. In this paper, we will improve on the method and save time by increasing the accuracy of displacement boundary conditions and using automatic node insertion and finite element analysis. The repeatability and robustness of the approach will be also studied, and its metrological performance will be analysed. We will apply the improved method on two industrial non-rigid parts with free-form surfaces simulated with different types of displacement, defect and measurement noise (for evaluation of robustness)
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