Analgesic Efficacy of Aloe Vera and Green Tea Mouthwash After Periodontal Pocket Reduction Surgery: A Randomized Split-Mouth Clinical Trial

Objectives: The aim of this study was to assess the efficacy of aloe vera and green tea mouthwash for reducing pain after periodontal pocket reduction surgery.Methods: This randomized, split-mouth, double-blind, cross-over clinical trial was carried out on 45 patients between 25 and 50 years of age requiring pocket reduction surgery. Patients underwent bilateral surgeries in two sessions. After the first surgery, the patients were randomized to receive either mouthwash or placebo for 10 days; then, each group used the other product for the same time period. The parameters assessed following each procedure were the numeric pain rating scale (NPRS) and number of painkillers taken by patients to alleviate postoperative pain. Also, patients were requested to report side effects, if any, after using the mouthwash.Results: The reported postoperative pain score was significantly lower after using the aloe vera and green tea mouthwash compared to the placebo only in the first postoperative day (P=0.002). Furthermore, number of analgesic tablets used in the first postoperative day was significantly lower than that in the control group (P=0.007).Conclusion: Our results indicated that patients experienced significantly less early postoperative pain when they used aloe vera and green tea mouthwash. Thus, its application can be recommended to decrease pain after periodontal pocket reduction surgery

Current natural bioactive materials in bone and tooth regeneration in dentistry: a comprehensive overview

Tissue regeneration is a vital phenomenon in the skeletal system of human beings during their life span. The structure of bony architecture and teeth are highly dependent to this ongoing procedure to maintain their functional form. Regarding the fundamental function of our skeletal system, all the involved components are at constant risk for injuries and deformations throughout the life. Therefore, in modern medicine, promotion of bone and tooth regeneration has become a critical counter measure to correct these acquired defects. There are numerous ways to address the bone and tooth related erosive pathologies but utilization of natural compounds has gained immense popularity in recent years. These materials provide a broad spectrum of therapeutic agents with a variety of biological characteristics. In this review, a comprehensive exploration has been implemented to extract and categorize the relevant scientific evidence on this issue, based on the source of natural candidates and the potential clinical indications. Database searching presented a considerable data pool with more than 300 references in this field. According to the results, all the proposed items can be categorized in two major groups including scaffolding and osteogenesis (or dentinogenesis) induction. The clinical applicability of a number of them is properly demonstrated in clinical trials but for the rest, more examinations are required to reach a conclusive decision