Concurrence of Stevens-Johnson Syndrome and Bilateral Parotitis after Minocycline Therapy

Minocycline is an antibiotic of tetracycline derivatives that is commonly used in the treatment of moderate to severe acne vulgaris. It has been reported to cause rare adverse events from mild cutaneous eruption to severe forms including drug-induced lupus, serum sickness-like reaction, and hypersensitivity reactions, etc. The risks of adverse events attributed to minocycline have not been ascertained reliably and there are concerns about the safety of minocycline which could possibly result in life-threatening events such as the Stevens-Johnson syndrome. Here we demonstrate an unusual case of Stevens-Johnson syndrome in conjunction with bilateral parotitis after the intake of minocycline in a Korean boy suggesting discreet use of the drug

EventSR: From Asynchronous Events to Image Reconstruction, Restoration, and Super-Resolution via End-to-End Adversarial Learning

Event cameras sense intensity changes and have many advantages over conventional cameras. To take advantage of event cameras, some methods have been proposed to reconstruct intensity images from event streams. However, the outputs are still in low resolution (LR), noisy, and unrealistic. The low-quality outputs stem broader applications of event cameras, where high spatial resolution (HR) is needed as well as high temporal resolution, dynamic range, and no motion blur. We consider the problem of reconstructing and super-resolving intensity images from LR events, when no ground truth (GT) HR images and down-sampling kernels are available. To tackle the challenges, we propose a novel end-to-end pipeline that reconstructs LR images from event streams, enhances the image qualities and upsamples the enhanced images, called EventSR. For the absence of real GT images, our method is primarily unsupervised, deploying adversarial learning. To train EventSR, we create an open dataset including both real-world and simulated scenes. The use of both datasets boosts up the network performance, and the network architectures and various loss functions in each phase help improve the image qualities. The whole pipeline is trained in three phases. While each phase is mainly for one of the three tasks, the networks in earlier phases are fine-tuned by respective loss functions in an end-to-end manner. Experimental results show that EventSR reconstructs high-quality SR images from events for both simulated and real-world data.Comment: Accepted by CVPR 202

Rheological method for alpha test evaluation of developing superplasticizers' performance: Channel flow test

Advance in high-range water-reducing admixture revolutionizes the workability and constructability of conventional vibrated concrete as well as self-consolidating concrete. Its need from construction fields has increased, and consequently a variety of new-type polycarboxylates, base polymers for the admixture, are being formulated in these days. Synthesizing new polymers needs a quick, but reliable, test to evaluate its performance on concrete. The test is also asked for selecting the best applicable brand of them before a test concrete will be mixed. This paper proposes a channel flow test and its usage for the purpose. The proposed procedure for the test includes the mix proportion of a test mortar, the test method, and rheological interpretation of the test results.ope

Ultraviolet photodepletion spectroscopy of dibenzo-18-crown-6-ether complexes with alkali metal cations

Ultraviolet photodepletion spectra of dibenzo-18-crown-6-ether complexes with alkali metal cations (M+-DB18C6, M = Cs, Rb, K, Na, and Li) were obtained in the gas phase using electrospray ionization quadrupole ion-trap reflectron time-of-flight mass spectrometry. The spectra exhibited a few distinct absorption bands in the wavenumber region of 35450−37800 cm^(−1). The lowest-energy band was tentatively assigned to be the origin of the S_0-S_1 transition, and the second band to a vibronic transition arising from the “benzene breathing” mode in conjunction with symmetric or asymmetric stretching vibration of the bonds between the metal cation and the oxygen atoms in DB18C6. The red shifts of the origin bands were observed in the spectra as the size of the metal cation in M^+-DB18C6 increased from Li^+ to Cs^+. We suggested that these red shifts arose mainly from the decrease in the binding energies of larger-sized metal cations to DB18C6 at the electronic ground state. These size effects of the metal cations on the geometric and electronic structures, and the binding properties of the complexes at the S_0 and S_1 states were further elucidated by theoretical calculations using density functional and time-dependent density functional theories

Anti-anxiety effect of methanol extract of Pericarpium zanthoxyli using a strychnine-sensitive glycine receptor model

Purpose: To determine if the methanol extract of Pericarpium zanthoxyli exerts anti-anxiety effects and also to explore any probable anti-anxiety mechanism in vivo.Methods: The staircase test, elevated plus maze test, rota-rod treadmill test and convulsions induced by strychnine and picrotoxin on mice were tested to identify potential mechanism of anti-anxiety activity of the plant extract.Results: The plant extract (10 mg/kg, p.o.) significantly reduced rearing numbers in the staircase test while it increased the time spent in the open arms as well as the number of entries to the open arms in the elevated plus maze test, suggesting that it has significant anti-anxiety activity. Furthermore, the extract inhibited strychnine-induced convulsion. However, it had little effect on picrotoxin-induced convulsion, suggesting that its anti-anxiety activity may be linked to strychnine-sensitive glycine receptor and not GABA receptor.Conclusion: These results suggest that the Pericarpium zanthoxyli extract may be beneficial for the control of anxiety.Keywords: Anti-anxiety, Pericarpium zanthoxyli, Glycine Receptor, GABA Recepto

Effects of paramagnetic fluctuations on the thermochemistry of MnO (100) surfaces in the oxygen evolution reaction

We investigated the effects of paramagnetic (PM) fluctuations on the thermochemistry of the MnO(100) surface in the oxygen evolution reaction (OER) using the "noncollinear magnetic sampling method \textit{plus} $U$" (NCMSM$+U$). Various physical properties, such as the electronic structure, free energy, and charge occupation, of the MnO (100) surface in the PM state with several OER intermediates, were reckoned and compared to those in the antiferromagnetic (AFM) state. We found that PM fluctuation enhances charge transfer from a surface Mn ion to each of the intermediates and strengthens the chemical bond between them, while not altering the overall features, such as the rate determining step and resting state, in reaction pathways. The enhanced charge transfer can be attributed to the delocalized nature of valence bands observed in the PM surface. In addition, it was observed that chemical-bond enhancement depends on the intermediates, resulting in significant deviations in reaction energy barriers. Our study suggests that PM fluctuations play a significant role in the thermochemistry of chemical reactions occurring on correlated oxide surfaces.Comment: Maintext: 15 pages, 3 figures 2 tables; SI: 3 pages, 2 figure

Preliminary evidence for the psychophysiological effects of technologic feature in e-commerce

As information and communication technologies are advanced, consumers are now able to enhance their e-commerce experiences regardless the channel, and it leads fashion retailers to develop better innovative experiential strategy to secure sustainable competency. The purpose of this study is to focus on apparel website to investigate the effect of branded contents on consumer\u27s pleasure and arousal that in turn may influence consumer\u27s response behaviors. This study employed S-O-R paradigm which explains that consumers\u27 inner organisms change according to the exposed external stimulation, and the changes antedate behavioral responses. Pleasure and arousal were measured with BioPAC MP150, which indicates the changes of electromyogram (EMG: pleasure), galvanic skin reflex (GSR: arousal), and heart rate (HR: pleasure) follow by the self-reported survey about behavioral responses. This study found that the effect for e-commerce\u27s branded content video on consumer\u27s response is indirect, and change of arousal is an indicator of hedonic shopping behavior