KINEMATIC ANALYSIS ON THE PUNT KICK IN FOOTBALL GOALKEEPER

The present study aimed to investigate punt kicks by football goalkeepers on the basis of differences in the effort of the kick. Twelve experienced goalkeepers participated in the study. The participants were made aware that for the maximum distance trial (the 100% trial), they should send the ball as far as possible, and for the 80% and 60% trials they should have a more controlled approach. Punt kicks were divided into three phases: the phase of release of the ball from the left hand (BR), the phase of pivot foot ground-contact (LFC), and the phase of the ball impact (IMP). Right hip and knee joint angles were calculated. In comparison to lower intensity punt kicks, the higher effort punt kicks involved increasing the hip joint extension angle for the right foot during the backswing and lowering the knee joint angle of the right leg at the start of the forward swing, thereby producing forward swing velocity for the right foot

INFLUENCE OF THE BALL SPEED ON THE DISPLACEMENT OF THE CENTER OF GRAVITY DURING BASEBALL BATTING MOTION

The purpose of this study was to investigate the modification in batting motion with different pitching speeds focusing on differences in batting technical level. The subjects were 10 experienced university baseball player. The subjects batted toward the center field, both fastballs and slowballs, aimed near the center of the strike zone from a pitching machine. Data were collected using a three dimensional automatic motion analysis system (Vicon MX). The displacement of the center of gravity(CG) were computed. Significant differences were seen due to difference in pitching speed in unskilled player. Conversely, in skilled player, no significant difference was found in the movement of CG due to the difference in pitching speed. It was revealed that it was not preferable for movement of the CG to fluctuate by difference in pitching speeds

KINEMATIC ANALYSIS OF BASEBALL BATTING MOTION WHEN BATTING PITCHES WITH VARYING VELOCITIES

The purpose of this study was to identify effect of moving the center of gravity of the body and rotating the torso when batting pitches with varying velocity. The subjects were 10 experienced university baseball player. The subjects batted toward the center field, both fastballs and slowballs, aimed near the center of the strike zone from a pitching machine. Data were collected using a three dimensional automatic motion analysis system (Vicon MX). The rotation angle of the torso and displacement of the center of gravity were computed. Due to differences in the shoulder rotation from the latter half of stepping leg touchdown through impact, we believe that the motion is adapted to pitch differences starting from the latter half of stepping leg touchdown. Comparing the shift in the center of gravity of the body during fastballs and slowballs, the forward motion and downward sinking of the center of gravity were significantly larger for slowballs

Effects of Olopatadine Hydrochloride, a Histamine H1 Receptor Antagonist, on Histamine-Induced Skin Responses

Effects of olopatadine hydrochloride, a histamine H1 receptor antagonist, on histamine-induced skin responses were evaluated in 10 healthy subjects in comparison with placebo, fexofenadine hydrochloride, and bepotastine besilate. Olopatadine significantly suppressed histamine-induced wheal, flare, and itch, starting 30 minutes after oral administration. Olopatadine was more effective than fexofenadine and bepotastine. None of the drugs studied impaired performance of word processing tasks. These results suggest that olopatadine can suppress skin symptoms caused by histamine soon after administration

High glucose level and angiotensin II type 1 receptor stimulation synergistically amplify oxidative stress in renal mesangial cells

Abstract Oxidative stress in renal mesangial cell causes diabetic glomerular changes. High glucose levels and angiotensin II (Ang II) are known to stimulate superoxide production in renal mesangial cells. However, it has been unclear whether Ang II stimulation and pre-conditioning with high glucose affects the same pathway of superoxide production in renal mesangial cells or not. In this study, we examined the levels of oxidative stress under Ang II stimulation in renal mesangial cells preincubated for six hours at various glucose levels. Intracellular levels of reactive oxidative species (ROS) were measured using dihydroethidium or 5′,6′-chloromethyl- 2′,7′ dichlorodihydro-fluorescein diacetate, which facilitates the detection of intracellular ROS under real-time fluorescent microscope. Ang II-induced elevated intracellular ROS levels were detected only when the cells were pre-incubated with high levels of glucose (13.5 mM, 27.8 mM), but was not detected under normal glucose condition (5.5 mM). Production of Ang II-induced intracellular ROS was higher under pre-treatment with 27.8 mM glucose compared to pretreatment with 13.5 mM glucose level. This ROS production in mesangial cells was induced within several minutes of the initiation of Ang II stimulation under high glucose levels. The production of intracellular ROS was significantly reduced in the presence of angiotensin II type1-receptor (AT1R) antagonist, whereas it was augmented in the presence of angiotensin II type2-receptor antagonist. In conclusion, Ang II-induced oxidative stress was augmented by high glucose levels and ROS levels were further alleviated in the presence of AT1R antagonists