1,714 research outputs found
Radio and affective rhythm in the everyday
This article explores the role of radio sound in establishing what I term ‘affective rhythms’ in everyday life. Through exploring the affective qualities of radio sound and its capacity for mood generation in the home, this article explores personal affective states and personal organisation. The term affective rhythm relates both to mood, and to routine. It is the combination of both that allows the possibility of thinking about sound and affect, and how they relate to, and integrate with, routine everyday life. The notion of ‘affective rhythm’ forces us to consider the idea of mood in the light of the routine nature of everyday domestic life
PACMAS state of media and communication report 2013
The PACMAS State of Media and Communication Report 2013 was undertaken through a partnership between RMIT University (Australia), the University of Goroka (Papua New Guinea) and UNITEC (New Zealand). The research for this report was developed and undertaken between June 2012 and April 2013 across 14 Pacific Island nations: Cook Islands, Federated States of Micronesia, Fiji, Kiribati, Republic of the Marshall Islands, Republic of Nauru, Niue, Republic of Palau, Papua New Guinea, Samoa, Solomon Islands, Tonga, Tuvalu, and Vanuatu. The report provides a regional overview of the PACMAS key components (Media Policy, Media Systems, Media Capacity Building and Media Content) as they emerged through 212 interviews focused upon the six PACMAS strategic areas. It also provides basic background information, an overview of the media and communications landscape and discusses in detail media and communications technicians; emergency broadcast systems, Technical and Vocational Education and Training (TVETs), media associations, climate change and non-communicable diseases (NCDs). For this reason, observations on the four PACMAS components should be understood to represent changes in the media and communication environment based upon an investigation focused on the PACMAS strategic activities. Part 1 & Part II of the report make up a Regional Overview of the State of Media and Communication in the Pacific. The report also includes 14 separate Country Reports which provide additional information on the media and communications landscape specific to each of the Pacific Island countries included in the PACMAS program. The country reports were written with the objectives of the PACMAS program in mind, however they may have utility for media, communication and development practitioners across the region
Inflammatory responses in primary muscle cell cultures in Atlantic salmon (Salmo salar)
Peer reviewedPublisher PD
Proteomic investigation of the genome-reduced pathogen, Mycoplasma hyopneumoniae
University of Technology Sydney. Faculty of Science.Mycoplasma hyopneumoniae is a genome-reduced bacterium and an economically significant pathogen that chronically infects the respiratory tract of swine. This infection often leads to pneumonia and secondary infections, costing agricultural industries significantly in the use of antibiotics and vaccines, which are currently largely ineffective. An improved understanding of the molecular mechanisms behind the infection process is essential to our ability to rationally design better vaccine and therapeutic interventions. With fewer than 700 predicted protein coding sequences, M. hyopneumoniae possesses one of the smallest genomes of any free-living organism. As such, it lends itself well to thorough proteomic interrogation.
In this thesis, a range of proteomic techniques have been used to investigate the M. hyopneumoniae global and surface proteome at the protein and peptide level, including surface shaving and labelling techniques, ligand and immuno-blotting and affinity chromatography, as well as N-terminal dimethyl labelling to determine true N-termini of mature proteins. This conceptually unbiased, function-oriented approach has revealed an unexpected level of complexity in the use of proteolytic processing, multifunctional proteins and moonlighting to compensate for reduced coding capacity at the genome level. While microarray and transcriptome studies suggest that under normal culture conditions, the majority of genes are transcribed; our analyses identified less than 400 detectable expressed protein products under similar conditions. A significant number of the expressed proteins were discovered to be multifunctional, post-translationally modified by proteolysis.
Surface proteome analyses identified a range of proteins to be surface exposed, despite lacking known signal peptides. Even though many of these proteins had well-characterised functions in the cytoplasm, they were also identified to have secondary functions at the cell surface, a phenomenon known as moonlighting. Many of the proteins present at the cell surface were identified to be subjected to proteolytic cleavage events. These were predominantly cell surface adhesins, many of which have already been described in the literature, however a large number of cytoplasmic “housekeeping” proteins are also found to be post-translationally cleaved, multifunctional proteins or moonlighting proteins.
These findings can be applied to improve the rational design and development of vaccines and therapeutics for the prevention and treatment of Mycoplasma hyopneumoniae, as well as having wider implications for the field of biology as a whole, if similar levels of post-translational regulation can be found in other bacterial pathogens
La figura del Procuratore negli organismi di giustizia internazionale
L'elaborato ha come oggetto l'evoluzione della figura del Procuratore quale organo d'accusa negli istituti di giustizia internazionale. La prima esperienza di Procuratore si ha nell'ambito dei Tribunali ad hoc per la ex-Jugoslavia e per il Ruanda, per poi essere ripresa e sviluppata anche nel primo tribunale penale internazionale a carattere permanente, ovvero la Corte Penale Internazionale. Nell'ultimo capitolo si analizza la nuova figura del Procuratore Europeo avanzata dalla Commissione UE e competente per i reati lesivi degli interessi finanziari dell'Unione Europe
Interfacial Dzyaloshinskii-Moriya interaction in Pt/CoFeB films: effect of the heavy-metal thickness
We report the observation of a Pt layer thickness dependence on the induced
interfacial Dzyaloshinskii-Moriya interaction in ultra-thin
Pt()/CoFeB films. Taking advantage of the large spin-orbit
coupling of the heavy metal, the interfacial Dzyaloshinskii-Moriya interaction
is quantified by Brillouin light scattering measurements of the frequency
non-reciprocity of spin-waves in the ferromagnet. The magnitude of the induced
Dzyaloshinskii-Moriya coupling is found to saturate to a value
mJm for Pt thicknesses larger than nm. The experimental
results are explained by analytical calculations based on the 3-site indirect
exchange mechanism that predicts a Dzyaloshinskii-Moriya interaction at the
interface between a ferromagnetic thin layer and a heavy metal. Our findings
open up a way to control and optimize chiral effects in ferromagnetic thin
films through the thickness of the heavy metal layer
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