14 research outputs found
Supplementary Table S4 from Characterization of Immunosuppressive Myeloid Cells in Merkel Cell Carcinoma: Correlation with Resistance to PD-1 Pathway Blockade
MNP and M-MDSC gene signatures used for myeloid clusters validation</p
Supplementary Table S2 from Characterization of Immunosuppressive Myeloid Cells in Merkel Cell Carcinoma: Correlation with Resistance to PD-1 Pathway Blockade
DEG of all clusters</p
Supplementary Figure S6 from Characterization of Immunosuppressive Myeloid Cells in Merkel Cell Carcinoma: Correlation with Resistance to PD-1 Pathway Blockade
Multivariate models resemble similar results to univariate model: Higher levels of TAMs markers relative to CD8 T cells are associated with worse prognosis.</p
Supplementary Figure S2 from Characterization of Immunosuppressive Myeloid Cells in Merkel Cell Carcinoma: Correlation with Resistance to PD-1 Pathway Blockade
Transcriptomics analysis demonstrate differences between TAMs and DCs.</p
Supplementary Figure S8 from Characterization of Immunosuppressive Myeloid Cells in Merkel Cell Carcinoma: Correlation with Resistance to PD-1 Pathway Blockade
Higher levels of S100A8 expressing cells relative to CD8 T cells in responding MCC tumors are associated with shorter duration of response.</p
Supplementary Table S1 from Characterization of Immunosuppressive Myeloid Cells in Merkel Cell Carcinoma: Correlation with Resistance to PD-1 Pathway Blockade
Antibodies information</p
Supplementary Figure S9 from Characterization of Immunosuppressive Myeloid Cells in Merkel Cell Carcinoma: Correlation with Resistance to PD-1 Pathway Blockade
Spatial analysis of tumors with high CD8 infiltration did not show different in the proximity or clustering of myeloid cells markers or phenotypes near CD8 T cells between the response groups.</p
Supplementary Figure S5 from Characterization of Immunosuppressive Myeloid Cells in Merkel Cell Carcinoma: Correlation with Resistance to PD-1 Pathway Blockade
Results of ROC space comparing CD8 percentage, MDSC-Mac/CD8 and Mono-Mac ratios as a in three patients groups stratified by CD8 levels.</p
Supplementary Table S3 from Characterization of Immunosuppressive Myeloid Cells in Merkel Cell Carcinoma: Correlation with Resistance to PD-1 Pathway Blockade
DEG for myeloid clusters</p