The high-energy galactic tau neutrino flux and its atmospheric background

We compare the tau neutrino flux arising from the galaxy and the earth atmosphere for $10^{3} \leq E/{GeV} \leq 10^{11}$. The intrinsic and oscillated tau neutrino fluxes from both sources are considered. We find that, for $E\geq 10^3$ GeV, the oscillated $\nu_{\tau}$ flux along the galactic plane dominates over the maximal intrinsic atmospheric $\nu_{\tau}$ flux, i.e., the flux along the horizontal direction. We also briefly comment on the prospects for observing these high-energy tau neutrinos.Comment: 3 pages, 2 figures, talk presented in EPS03, Aachen, German

Applications of Transmission Electron Microscopy to Coal

Coal consists of a hydrocarbon matrix in which minerals are embedded. The hydrocarbon matter also contains impurities distributed as individual atoms. Thus, coal has phases similar to those in metallic or ceramic alloy systems; a matrix, included precipitates and atoms distributed individually in solid solution. Consequently, techniques of electron microscopy developed to examine metallic and ceramic alloy systems are directly applicable to coal. We report application of microanalytical techniques of electron microscopy to coal using examples of measurements for several coals. Identification and characterization of clays and sulfides is described. Use of x-ray emission spectroscopy for organic element measurement is emphasized

Inhibition of dengue virus replication by novel inhibitors of RNA-dependent RNA polymerase and protease activities

Dengue virus (DENV) is the leading mosquito-transmitted viral infection in the world. With more than 390 million new infections annually, and up to 1 million clinical cases with severe disease manifestations, there continues to be a need to develop new antiviral agents against dengue infection. In addition, there is no approved anti-DENV agents for treating DENV-infected patients. In the present study, we identified new compounds with anti-DENV replication activity by targeting viral replication enzymes – NS5, RNA-dependent RNA polymerase (RdRp) and NS3 protease, using cell-based reporter assay. Subsequently, we performed an enzyme-based assay to clarify the action of these compounds against DENV RdRp or NS3 protease activity. Moreover, these compounds exhibited anti-DENV activity in vivo in the ICR-suckling DENV-infected mouse model. Combination drug treatment exhibited a synergistic inhibition of DENV replication. These results describe novel prototypical small anti-DENV molecules for further development through compound modification and provide potential antivirals for treating DENV infection and DENV-related diseases

Lagrangian Floer superpotentials and crepant resolutions for toric orbifolds

We investigate the relationship between the Lagrangian Floer superpotentials for a toric orbifold and its toric crepant resolutions. More specifically, we study an open string version of the crepant resolution conjecture (CRC) which states that the Lagrangian Floer superpotential of a Gorenstein toric orbifold $\mathcal{X}$ and that of its toric crepant resolution $Y$ coincide after analytic continuation of quantum parameters and a change of variables. Relating this conjecture with the closed CRC, we find that the change of variable formula which appears in closed CRC can be explained by relations between open (orbifold) Gromov-Witten invariants. We also discover a geometric explanation (in terms of virtual counting of stable orbi-discs) for the specialization of quantum parameters to roots of unity which appears in Y. Ruan's original CRC ["The cohomology ring of crepant resolutions of orbifolds", Gromov-Witten theory of spin curves and orbifolds, 117-126, Contemp. Math., 403, Amer. Math. Soc., Providence, RI, 2006]. We prove the open CRC for the weighted projective spaces $\mathcal{X}=\mathbb{P}(1,\ldots,1,n)$ using an equality between open and closed orbifold Gromov-Witten invariants. Along the way, we also prove an open mirror theorem for these toric orbifolds.Comment: 48 pages, 1 figure; v2: references added and updated, final version, to appear in CM

Scalar-Torsion Mode in a Cosmological Model of the Poincar\'{e} Gauge Theory of Gravity

We investigate the equation of state (EoS) of the scalar-torsion mode in Poincar\'{e} gauge theory of gravity. We concentrate on two cases with the constant curvature solution and positive kinetic energy, respectively. In the former, we find that the torsion EoS has different values in the various stages of the universe. In particular, it behaves like the radiation (matter) EoS of $w_r=1/3$ ($w_m=0$) in the radiation (matter) dominant epoch, while in the late time the torsion density is supportive for the accelerating universe. In the latter, our numerical analysis shows that in general the EoS has an asymptotic behavior in the high redshift regime, while it could cross the phantom divide line in the low redshift regime.Comment: 12 pages, 2 figures, title changed, revised version accepted for publication in JCA

Gamma-ray Constraints on Effective Interactions of the Dark Matter

Using an effective interaction approach to describe the interactions between the dark matter particle and the light degrees of freedom of the standard model, we calculate the gamma-ray flux due to the annihilation of the dark matter into quarks, followed by fragmentation into neutral pions which subsequently decay into photons. By comparison to the mid-latitude data released from the Fermi-LAT experiment, we obtain useful constraints on the size of the effective interactions and they are found to be comparable to those deduced from collider, gamma-ray line and anti-matter search experiments. However, the two operators induced by scalar and vector exchange among fermionic dark matter and light quarks that contribute to spin-independent cross sections are constrained more stringently by the recent XENON100 data.Comment: 22 pages, 4 figures; title fixed and a couple of references adde