Endobronchial Ultrasound-guided Transbronchial Needle Aspiration for the Diagnosis of Intrathoracic Lesions : Experience of a Single Academic Medical Center

Article信州医学雑誌 60(5): 249-255(2012)journal articl

Current Status of Cancer Genomic Profiling Test in Shinshu University Hospital

Introduction : Comprehensive Cancer Genomic Profiling Tests (CGP) were approved for Japanese health insurance in June 2019. Shinshu University Hospital is designated as a cancer genome hub hospital and has the function to conduct CGP and expert panel to assign clinical meaning to the results. Material and methods : We retrospectively analyzed the data of CGP and the expert panel in Shinshu University Hospital and the liaison hospitals in Nagano prefecture from January 2020 to December 2022. Results : A total of 296 patients (mean age 60.0 years, men/female 127/169) received CGP in our hospital. 90, 164, and 41 patients received NCC Oncopanel System, FoundationOne®CDx, and FoundationOne®Liquid CDx, respectively. We could present genetically compatible treatments based on the CGP test to 43 cases (14.5 ％). 14 cases have been found to have presumed germline pathogenic variants, and 10 cases among them were received genetic counseling. Conclusion. ; The number of cancer patients receiving CGP in our hospital or Nagano Prefecture is increasing. But there are several issues to be addressed, such as conducting the clinical studies in our institution to increase the patients who can reach to the new adequate treatment.Article信州医学雑誌 72(3) : 141-148, (2024)journal articl