55 research outputs found
Biopuces pour le traitement de cellules vivantes : micromanipulation des cellules par voie électrique ou microfluidique
IISMM – Institut d’études de l’Islam et des sociétés du monde musulman
Frédéric Hitzel, chargé de recherche au CNRSTimour Muhidine, chargé de cours à l’INaLCO Art, patrimoine et cultures dans le monde turc et ottoman À ce séminaire, sept intervenants ont accepté de participer pour présenter leurs travaux de recherche en cours et faire partager leur expérience professionnelle. Le 16 novembre 2011, le séminaire a accueilli le poète, essayiste et éditeur turc Enis Batur. Auteur de nombreux essais et romans, dont plusieurs sont traduits en français, il est l’une des..
Single Vegetal Cell Handling and Fixing in a Micro-fluidic Device
International audienceThe basic advantage of the microfluidic systems is that they enable reducing consumption of biological material and chemicals. But another major advantage of the microfluidic systems, not widely explored so far, is that with feature sizes reduced toward the size of cells, one can easily handle and fix a single cell. The interest of single cell handling and fixing appears when one wants to study biochemical exchanges between single cells or internal biochemical reactions inside an isolated cell. This work uses the shape of the microfluidc device to control the migration and placement of single vegetal cells. Three-dimensional micro-molding and poly-dimethylsiloxane (PDMS) patterning techniques have been used to realize device prototypes. Double-height micro-molds are made of thick negative photoresist (SU8) Experiments have been undergone to optimize fluid rate flow and cell concentration regarding to right cell placement percentage. The PDMS prototypes systems confirm the good operation of the design to migrate cells, place and fix them. The placement rate, even if it is enough for statistical biochemical experiments, will be improved by the use of new material. New material will allow to get rid of air bubbles due to PDMS long-term hydrophobicity that render up to 25% settlement places unserviceable
A Microfluidic Device for Long-Term Study of Individual Cells
International audienceThis paper presents the original design of a microfluidic device for long-term study of individual cells. This paper describes how the microfluidic device works to handle and trap a single cell in each one of multiple channels. The vascularization networks and the special compacted shape of the device render it suitable for long-term viability of cells and biological statistical study or drug screening
A Microfluidic Device for Long-Term Study of Individual Cells
International audienceThis paper presents the original design of a microfluidic device for long-term study of individual cells. This paper describes how the microfluidic device works to handle and trap a single cell in each one of multiple channels. The vascularization networks and the special compacted shape of the device render it suitable for long-term viability of cells and biological statistical study or drug screening
研究解説 : 3-D Microsystem Packaging for Interconnecting Electrical, Optical and Mechanical Microdevices to The Eexternal World.
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