Conceptual model of E. coli transcriptional machinery

At the moment one type of analysis of transcription regulatory networks (TRNs) in prokaryotes is topological analysis of graph structure of possible regulatory interaction links (see for example [1]). That type of analysis takes into account possibility links that designate the fact that one gene product in some conditions can modulate transcription of the other. The benefit of such approach is that it is allow analyzing TRN at the whole cell level. At the same type it is known that at least some responses are regulated by abundance of elements of transcription machinery [2-3]. We have developed conceptual model of whole cell E. coli TRN with SBGN ER, SBGN PD and SBGN AF languages [4]. That model is the first step towards incorporation of some quantitative information into whole cell TRN modeling.

1.	Freyre-González et al. Functional architecture of Escherichia coli: new insights provided by a natural decomposition approach. Genome Biol (2008) vol. 9 (10) pp. R154
2.	Klumpp and Hwa. Growth-rate-dependent partitioning of RNA polymerases in bacteria. Proc Natl Acad Sci USA (2008) vol. 105 (51) pp. 20245-50
3.	Barker et al. Mechanism of regulation of transcription initiation by ppGpp. II. Models for positive control based on properties of RNAP mutants and competition for RNAP. J Mol Biol (2001) vol. 305 (4) pp. 689-702
4.	Le Novère et al. The systems biology graphical notation. Nature biotechnology (2009) vol. 27 (8) pp. 735-41
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The Implementation of Bela Negara Value in Citizenship Education in the Efforts to Prevent Radicalism

Having a perspective and understanding of radicalism alone is not enough to make someone involved into terrorism. However, the radicalism that leads to the acts of terrorism must be prevented early on by every country either through optimizing the country's defense, or the ability of its citizen as a person and also as group, as well. Various efforts to spread the seeds of radicalism under the guise of religion until this day are still life in colleges. This research use qualitative method with descriptive analytics approach, and collected relevant data through study of literatures. The systematic implementation of the bela negara program in numerous educational institutions including in universities will be assessed if it is effective in stemming radical ideologies that continue to threaten the existence of the National Security. Keywords: Radicalism, Terrorism, Bela Negara, College, and National Security DOI: 10.7176/RHSS/10-18-10 Publication date:September 30th 202

Probing new physics with coherent neutrino scattering off nuclei

The possibility off measuring for the first time neutrino-nuclei coherent scattering has been recently discussed by several experimental collaborations. It is shown that such a measurement may be very sensitive to non-standard interactions of neutrinos with quarks and might set better constraints than those coming from future neutrino factory experiments. We also comment on other types of new physics tests, such as extra heavy neutral gauge bosons, where the sensitivity to some models is slightly better than the Tevatron constraint and, therefore, could give complementary bounds.Comment: 15 pages, 4 figures Discussion about Z prime corrected and extended. Final version to be published in JHE

Visualizing plasmon-exciton polaritons at the nanoscale using electron microscopy

Polaritons are compositional light-matter quasiparticles that have recently enabled remarkable breakthroughs in quantum and nonlinear optics, as well as in material science. Despite the enormous progress, however, a direct nanometer-scale visualization of polaritons has remained an open challenge. Here, we demonstrate that plasmon-exciton polaritons, or plexcitons, generated by a hybrid system composed of an individual silver nanoparticle and a few-layer transition metal dichalcogenide can be spectroscopically mapped with nanometer spatial resolution using electron energy loss spectroscopy in a scanning transmission electron microscope. Our experiments reveal important insights about the coupling process, which have not been reported so far. These include nanoscale variation of Rabi splitting and plasmon-exciton detuning, as well as absorption-dominated extinction signals, which in turn provide the ultimate evidence for the plasmon-exciton hybridization in the strong coupling regime. These findings pioneer new possibilities for in-depth studies of polariton-related phenomena with nanometer spatial resolution