The moral impact of studying science

Science and religion are most usually compared on epistemic grounds: what do they tell us about the natural world and what methods do they use to determine those truths? The suggestion here is that the two fields should be compared on moral grounds: how do scientific and religious experiences affect the way a person lives his or her life? A hypothesis is presented in this vein: engaging in scientific work or education alters a person’s moral outlook on everyday matters. In this chapter, I articulate and motivate this claim by framing it against both theological and philosophical debate. I explore how it might be tested as a claim in moral psychology. The resulting vision presented here is of science and religion engaged in dialogue—at times necessarily embroiled—not only about the nature of the world, but regarding how best we navigate our way in it

The earliest thymic T cell progenitors sustain B cell and myeloid lineage potential

The stepwise commitment from hematopoietic stem cells in the bone marrow to T lymphocyte-restricted progenitors in the thymus represents a paradigm for understanding the requirement for distinct extrinsic cues during different stages of lineage restriction from multipotent to lineage-restricted progenitors. However, the commitment stage at which progenitors migrate from the bone marrow to the thymus remains unclear. Here we provide functional and molecular evidence at the single-cell level that the earliest progenitors in the neonatal thymus had combined granulocyte-monocyte, T lymphocyte and B lymphocyte lineage potential but not megakaryocyte-erythroid lineage potential. These potentials were identical to those of candidate thymus-seeding progenitors in the bone marrow, which were closely related at the molecular level. Our findings establish the distinct lineage-restriction stage at which the T cell lineage-commitment process transits from the bone marrow to the remote thymus. © 2012 Nature America, Inc. All rights reserved