Feed rate modeling in circular–circular interpolation discontinuity for high-speed milling

In this paper, a modeling approach is presented in order to evaluate feed rate during a circular interpolation in high-speed milling. The developed model depends on the type of discontinuity and the kinematic performance of the machine tool. To begin with, a feed rate modeling for circular interpolation with continuity in tangency is developed. After, the discontinuity in tangency between two circular interpolations is replaced by discontinuity in curvature by adding a fillet which is in relation to the functional tolerance ε imposed in the part design. An experimental study has been carried out to validate the models

Pilot optical alignment

PILOT (Polarized Instrument for Long wavelength Observations of the Tenuous interstellar medium) is a balloonborne astronomy experiment designed to study the polarization of dust emission in the diffuse interstellar medium in our Galaxy. The PILOT instrument allows observations at wavelengths 240 μm and 550 μm with an angular resolution of about two arcminutes. The observations performed during the two first flights performed from Timmins, Ontario Canada, and from Alice-springs, Australia, respectively in September 2015 and in April 2017 have demonstrated the good performances of the instrument. Pilot optics is composed of an off axis Gregorian type telescope combined with a refractive re-imager system. All optical elements, except the primary mirror, which is at ambient temperature, are inside a cryostat and cooled down to 3K. The whole optical system is aligned on ground at room temperature using dedicated means and procedures in order to keep the tight requirements on the focus position and ensure the instrument optical performances during the various phases of a flight. We’ll present the optical performances and the firsts results obtained during the two first flight campaigns. The talk describes the system analysis, the alignment methods, and finally the inflight performances

L’École et la Vie économique

Tapie G. L’École et la Vie économique . In: La revue pédagogique, tome 69, Juillet-Décembre 1916. pp. 55-65

L’École et la Vie économique

Tapie G. L’École et la Vie économique . In: La revue pédagogique, tome 69, Juillet-Décembre 1916. pp. 55-65

Osteopetrosis infantil maligna

Introducción: Osteopetrosis Infantil Maligna (OIM) es un grave e inusual desorden genético debido a una actividad osteoclástica anormal.Objetivo: Reportar lactante en quien se documentó una Osteopetrosis Infantil Maligna, revisando aspectos diagnósticos y terapéuticos más relevantes.Caso clínico: Reportamos un lactante de 10 meses de sexo masculino en quien se confirmó OIM tras presentar plaquetopenia y visceromegalias. En su historial destacó ser primer hijo de padres no consanguíneos, y entre sus hallazgos presentó hepatoesplenomegalia, plaquetopenia y anemia graves, compromiso sensorial visual y auditivo e infecciones a repetición. El diagnóstico fue confirmado mediante estudio genético, el cual identificó 2 mutaciones heterocigotas en el gen TCIRG1. Se realizó trasplante de precursores hematopoyéticos, sin haber presentado recuperación hematológica, falleciendo por enfermedad veno oclusiva.Discusión: La OIM es una enfermedad inusual, grave y de inicio temprano, siendo necesario un elevado índice de sospecha ante hepatoesplenomegalia y falla medular. El diagnóstico temprano y el trasplante de precursores hematopoyéticos son las únicas intervenciones potencialmente curativas de esta entidad letal.</jats:p

Marine monitoring campaign in France and French overseas departments: more than 10 000 datasets from grab and passive sampling

A screening study of emerging contaminants was carried out in 2012 in coastal waters in both metropolitan France and overseas departments (Martinique, Guadeloupe, Reunion, Mayotte and French Guiana) as part of the National Action Plan against pollution of the aquatic environment, which requires the regular updating of the lists of substances to be included in monitoring programmes. The Action Plan stresses the need to set up a watch list of substances to be investigated at the national level in order to acquire missing information about the level of exposure to emerging contaminants in the aquatic environment and allow identification of substances for which specific actions need to be implemented. The Ministry of Ecology appointed ONEMA as principal contractor and INERIS as project leader. One of the main objectives of this screening study was to gain knowledge of the occurrence of substances of “emerging” concern in the marine environment. Different data were collected, such as the presence/absence of each investigated compound and the level of concentration observed in the aquatic environment (water and sediment). Moreover, the performance of different sampling techniques was assessed. This study contributes to increased knowledge of emerging pollutants in French waters and to the wider considerations for updating the list of relevant substances to be included in the new monitoring programmes to be established. Triplicate sampling of water at the same site followed by SBSE extraction displayed a high results variability, which limits the exploitation of the quantified results. Neverthless, the testing of in situ systems integrators – POCIS – and extraction by SBSE bars has proven the added value of these two complementary techniques for monitoring hydrophobic and hydrophilic compounds in marine water. Finally, analyses of sediment allowed a more complete assessment of the quality of the waterbodies