HD 179949b - a close orbiting extrasolar giant planet with a stratosphere?

The original article can be found at: http://www3.interscience.wiley.com Copyright Blackwell Publishing. DOI: 10.1111/j.1365-2966.2008.13831.xWe have carried out a search for the 2.14-μm spectroscopic signature of the close orbiting extrasolar giant planet, HD179949b. High-cadence time-series spectra were obtained with the Cryogenic high-resolution InfraRed ´ Echelle Spectrograph at Very Large Telescope, Unit 1 on two closely separated nights. Deconvolution yielded spectroscopic profiles with mean signal-to-noise ratios of several thousand, enabling the near-infrared contrast ratios predicted for the HD179949 system to be achieved. Recent models have predicted that the hottest planets may exhibit spectral signatures in emission due to the presence of TiO and VO which may be responsible for a temperature inversion high in the atmosphere.We have used our phase-dependent orbital model and tomographic techniques to search for the planetary signature under the assumption of an absorption line dominated atmospheric spectrum, where T and V are depleted from the atmospheric model, and an emission line dominated spectrum, where TiO and VO are present. We do not detect a planet in either case, but the 2.120–2.174-μm wavelength region covered by our observations enables the deepest near-infrared limits yet to be placed on the planet/star contrast ratio of any close orbiting extrasolar giant planet system. We are able to rule out the presence of an atmosphere dominated by absorption opacities in the case of HD179949b at a contrast ratio of Fp/F∗ ∼ 1/3350, with 99 per cent confidence.Peer reviewe

Multi-trait genome-wide association study identifies new loci associated with optic disc parameters

A new avenue of mining published genome-wide association studies includes the joint analysis of related traits. The power of this approach depends on the genetic correlation of traits, which reflects the number of pleiotropic loci, i.e. genetic loci influencing multiple traits. Here, we applied new meta-analyses of optic nerve head (ONH) related traits implicated in primary open-angle glaucoma (POAG); intraocular pressure and central corneal thickness using Haplotype reference consortium imputations. We performed a multi-trait analysis of ONH parameters cup area, disc area and vertical cup-disc ratio. We uncover new variants; rs11158547 in PPP1R36-PLEKHG3 and rs1028727 near SERPINE3 at genome-wide significance that replicate in independent Asian cohorts imputed to 1000 Genomes. At this point, validation of these variants in POAG cohorts is hampered by the high degree of heterogeneity. Our results show that multi-trait analysis is a valid approach to identify novel pleiotropic variants for ONH

Limits on the 2.2- m contrast ratio of the close-orbiting planet HD 189733b

The definitive version is available at: www.blackwell-synergy.com. Copyright Balckwell Publishing DOI : 10.1111/j.1365-2966.2007.12394.xPeer reviewe