Criteria and Method for Detection of Circulating Tumor Cells

The purpose of the work is to form a complex of criteria for tumor malignancy evaluation and to improve the method of detecting circulating tumor cells in human blood.Мета роботи — формування комплексу критеріїв оцінювання злоякісності пухлини та удосконалення методу виявлення циркулюючих пухлинних клітин в крові людини.Предложенный метод определения циркулирующих опухолевых клеток, который является усовершенствованием технологии ISET, объединяет два этапа. На первом этапе осуществляется выделение ЦОК с совершенствованием за счет установки двух дополнительных поликарбонатных фильтров с порами диаметром 5 и 3 мкм и обеспечении режима 100% герметизации камеры гемолизации и постоянного давления в течение всего процесса фильтрации. На втором этапе при использовании сформированного комплекса критериев осуществляется определение степени злокачественности выделенных клеток. Использование разработанного метода в автоматизированной системе анализа цифровых микроскопических изображений циркулирующих опухолевых клеток обеспечивает определение и расчет характерных признаков для отнесения объекта к определенному классу злокачественности и формирования базы данных сканированных изображений с занесением имеющихся клеток или их образований, а также окончательную проверку результатов оценки злокачественности опухоли по шаблонаммаскам ЦОК и доброкачественной опухолевой клетки

Processing of aluminum-graphite particulate metal matrix composites by advanced shear technology

Copyright @ 2009 ASM International. This paper was published in Journal of Materials Engineering and Performance 18(9) and is made available as an electronic reprint with the permission of ASM International. One print or electronic copy may be made for personal use only. Systematic or multiple reproduction, distribution to multiple locations via electronic or other means, duplications of any material in this paper for a fee or for commercial purposes, or modification of the content of this paper are prohibited.To extend the possibilities of using aluminum/graphite composites as structural materials, a novel process is developed. The conventional methods often produce agglomerated structures exhibiting lower strength and ductility. To overcome the cohesive force of the agglomerates, a melt conditioned high-pressure die casting (MC-HPDC) process innovatively adapts the well-established, high-shear dispersive mixing action of a twin screw mechanism. The distribution of particles and properties of composites are quantitatively evaluated. The adopted rheo process significantly improved the distribution of the reinforcement in the matrix with a strong interfacial bond between the two. A good combination of improved ultimate tensile strength (UTS) and tensile elongation (e) is obtained compared with composites produced by conventional processes.EPSR

Contribution of various deformation mechanisms to the superplasticity of high speed tool steels

Translated from Russian (Fiz. Khim. Obrab. Mater. 1988 v. 22(2) p. 118-127)Available from British Library Document Supply Centre- DSC:9023.19(VR-Trans--4063)T / BLDSC - British Library Document Supply CentreSIGLEGBUnited Kingdo

Calculation of the thickness of the barrier coating requred in interaction between the metal melt and the carbon fibre

Translated from Russian (Fiz. Khim. Obrab. Mater. 1988 v. 22(3) p. 88-92)Available from British Library Document Supply Centre- DSC:9023.19(VR-Trans--4058)T / BLDSC - British Library Document Supply CentreSIGLEGBUnited Kingdo

Calculation of the thickness of the barrier coating requred in interaction between the metal melt and the carbon fibre

Translated from Russian (Fiz. Khim. Obrab. Mater. 1988 v. 22(3) p. 88-92)Available from British Library Document Supply Centre- DSC:9023.19(VR-Trans--4058)T / BLDSC - British Library Document Supply CentreSIGLEGBUnited Kingdo

Anthropogenic soils and landscapes of European Russia: Summer school from sea to sea—A didactic prototype

Field excursions and trainings are considered a key component of education programs in soil and environmental sciences. They allow mastering students’ practical skills in sampling and onsite assessments and improve understanding of ecosystem integrity and complexity. Urbanization has a substantial impact on soil properties and functions; however, field courses focused on urban soils are rare. We present a didactic prototype and the outcomes of the “Monitoring, Modeling, and Management of Urban Green Infrastructure and Soils (3MUGIS)” summer school—the first educational tour observing anthropogenic soils and landscapes along the bioclimatic gradient in European Russia, from tundra to dry steppes. Didactic learning was based on a studying-by-doing approach; students were involved in environmental assessment in multiple regions varying in climatic and socioeconomic features. Considering the high spatial heterogeneity of urban ecosystems, we used express techniques (portable X-ray fluorescence, infrared gas analyzers) for onsite soil analysis at multiple replicas. The data collected were discussed with local and international experts from Russia, Germany, the United States, and France in the context of regional environmental problems (e.g., pollution, soil degradation, and urban expansion). Students discovered zonal changes in vegetation (e.g., increasing tree height and diversity from north taiga to forest steppes) and soil properties (e.g., a gradual increase in pH and changes in soil organic C), as well as urban-specific processes and features (e.g., urban heat island effect or soil artifacts). The overall student feedback was very positive (50.8% excellent, 36% good); some specific organizational issues will be addressed for future 3MUGIS summer schools. © 2020 The Authors. Journal of Environmental Quality © 2020 American Society of Agronomy, Crop Science Society of America, and Soil Science Society of Americ