Electronic band structure and exchange coupling constants in ACr2X4 spinels

We present the results of band structure calculations for ACr2X4 (A=Zn, Cd, Hg and X=O, S, Se) spinels. Effective exchange coupling constants between Cr spins are determined by fitting the energy of spin spirals to a classical Heisenberg model. The calculations reproduce the change of the sign of the dominant nearest-neighbor exchange interaction J1 from antiferromagnetic in oxides to ferromagnetic in sulfides and selenides. It is verified that the ferromagnetic contribution to J1 is due to indirect hopping between Cr t2g and eg states via X p states. Antiferromagnetic coupling between 3-rd Cr neighbors is found to be important in all the ACr2X4 spinels studied, whereas other interactions are much weaker. The results are compared to predictions based on the Goodenough-Kanamori rules of superexchange.Comment: 15 pages, 10 figures, 3 table

Influence of р-thyrozol on the morphology and antioxidant-prooxidant balance in prostate of rats at sulpiride-induced benign prostatic hyperplasia

The aim of the research was to study the influence of p-thyrozol on the morphology and antioxidant-prooxidant balance in prostate of rats at sulpiride-induced benign prostatic hyperplasia. It was found that introduction of p-thyrozol promoted thwarting progress of pathological process that was proved by less degree of manifestation of proliferative processes in epithelium and of cellular infiltration of stroma. In addition, increase of antioxidant reserve of gland was registered

Динамика иммунного ответа слизистой оболочки долевого бронха у больных пневмонией

A quantitative composition of the immunocompetent cell subpopulations in mucous membrane of a lobar bronchus was studied in pneumonia patients according to the illness course. Features of the cell infiltrate composition in the proper lamina were revealed and a phenotypic characteristic of interepithelial lymphocytes in the lobar bronchus mucosa was found.Изучали количественный состав субпопуляций иммунокомпетентных клеток слизистой оболочки долевого бронха у больных пневмонией в динамике болезни. Выявили особенности состава клеточного инфильтрата собственной пластинки и определили фенотипическую характеристику межэпителиальных лимфоцитов слизистой оболочки долевого бронха в динамике пневмонии

ЭФФЕКТИВНОСТЬ ДЕЙСТВИЯ РЕГУЛЯТОРОВ ПРИРОДНОГО ПРОИСХОЖДЕНИЯ ПРИ ВЫРАЩИВАНИИ МОРКОВИ

Utilization of natural biostimulators- secondary metabolits of plants in carrot production was studied. Purified fractions with glycoside content are characterized with extraction and adsorption chromatography from the next plants: linarosides – from Linaria vulgaris Mill. L., melampyrosides - from Melampyrum nemorosum L., genistifoliosides - from Linaria genistifolia L., verbascosides - from Verbascum phlomoides L., melongosides - from Solanum melongena L. and tomatoside – from Solanum lycopersicum L. The former substance was registered under market mark “ecostim”. Prospective preparations for the improvement plant resistance to abiotic and biotic stresses have been identified in laboratory tests. Treatment of carrot seeds with water solutions of such substances accelerates plant growth, increases yield and improves quality of storage roots. We determined regimes of seed treatment (substance concentration, time of exposition) and gave recommends by using of natural regulators in the technologic scheme of carrot cultivation. Using secondary metabolites of higher plants stimulates the energy of germination (on 1,5-6,7%) and increases the field germination of carrot seeds (on 23-40%). It accelerates leaves growth and increases the mass of storage roots, improves biochemical characteristics of storage roots (accumulation the β- carotene and decreasing of nitrates content). Yield of storage roots increases on 4,2-8,5 t/ha, and yield of market quality roots increases on 4-6 t/ha.Изучена возможность использования природных биорегуляторов – вторичных метаболитов высших растений – в качестве элемента технологии при выращивании моркови. Из представителей сем. Solanaceae и Scrophularеaceaе методом экстракции и последующей адсорбционно-распределительной хроматографии получены и химически охарактеризованы очищенные гликозидсодержащие фракции: из Linaria vulgaris Mill. L. – линарозиды, из Melampyrum nemorosum L. - мелампирозиды, из Linaria genistifolia L. – генистифолиозиды, из Verbascum phlomoides L. - вербаскозиды, из Solanum melongena L. мелонгозиды и из Solanum lycopersicum L. разрешенный к применению препарат экостим на основе стероидного гликозида – томатозид. В процессе лабораторного тестирования выявлены наиболее перспективные соеди- нения, способные благодаря предпосевному замачиванию семян в их водных растворах, индуцировать устойчивость растений моркови к абиотическим и биотическим стрессам, что в свою очередь способствует ускорению роста, повышению урожайности и улучшению качества получаемой продукции. Определены оптимальные параметры обработки семян (концентрации биорегуляторов в водных растворах, время экспозиции семян), даны рекомендации по применению предпосевной обработки семян природными биорегуляторами в технологической схеме выращивания моркови. Использование вторичных метаболитов высших растений стимулирует энергию прорастания (на 1,5-6,7%) и повышает полевую всхожесть семян моркови (на 23-40%), обеспечивает дружное появление всходов и оптимальную густоту стояния. Это ускоряет динамику нарастания ассимиляционной поверхности растений и массы корнеплода, улучшает биохимические показатели конечной продукции, способствуя накоплению в них каротина и снижению нитратов. При этом урожайность увеличивается на 4,2-8,5 т/га, выход товарной продукции - на 4-6 т/га.

EFFICIENCY OF NATURAL GROWTH REGULATORS IN CARROT PRODUCTION

Utilization of natural biostimulators- secondary metabolits of plants in carrot production was studied. Purified fractions with glycoside content are characterized with extraction and adsorption chromatography from the next plants: linarosides – from Linaria vulgaris Mill. L., melampyrosides - from Melampyrum nemorosum L., genistifoliosides - from Linaria genistifolia L., verbascosides - from Verbascum phlomoides L., melongosides - from Solanum melongena L. and tomatoside – from Solanum lycopersicum L. The former substance was registered under market mark “ecostim”. Prospective preparations for the improvement plant resistance to abiotic and biotic stresses have been identified in laboratory tests. Treatment of carrot seeds with water solutions of such substances accelerates plant growth, increases yield and improves quality of storage roots. We determined regimes of seed treatment (substance concentration, time of exposition) and gave recommends by using of natural regulators in the technologic scheme of carrot cultivation. Using secondary metabolites of higher plants stimulates the energy of germination (on 1,5-6,7%) and increases the field germination of carrot seeds (on 23-40%). It accelerates leaves growth and increases the mass of storage roots, improves biochemical characteristics of storage roots (accumulation the β- carotene and decreasing of nitrates content). Yield of storage roots increases on 4,2-8,5 t/ha, and yield of market quality roots increases on 4-6 t/ha

Использование различных методов исследования процессов деления клеток эпителия и стромы на примере слизистой оболочки крупного хрящевого бронха

The results of cell fission research in the epithelium and the stroma of large bronchus mucosa was done in 10 healthy persons and 73 patients with acute pneumonia according to the course of the disease. Autoradiography with 3H-thymidine and immunohistochemistry with proliferating cell nuclear antigen (PCNA) were used. In all cases we obtained reliably high PCNA index of positive cell nuclei in comparison with a labeling level detected by the autoradiography. At the same time the labeling level dynamics in the epithelial and stroma cells of large bronchus mucosa maintained irrespective to the method used both in the healthy and in the course of the illness.Проведен анализ результатов исследования процессов клеточного деления в эпителии и строме слизистой оболочки крупных бронхов у здоровых лиц (10 человек) и больных острой пневмонией в динамике болезни (73 больных) методом авторадиографии с 3Н-тимидином и методом иммуногистохимии с PCNA. Во всех случаях получили достоверно высокий индекс PC/VA-положительных ядер клеток в сравнении с уровнем мечения, выявляемым методом авторадиографии с 3Н-тимидином. При этом закономерности изменения уровня мечения эпителиальных и стромальных клеток слизистой оболочки крупного бронха сохранялись независимо от используемого метода как в норме, так и в динамике болезни

STUDY OF DNA DAMAGE by NEW NORMOTHYMIC MEDICINAL ON THE BASIS OF THE COMPLEX OF LITHIUM CITRATE, POLYMETHYLSYLOXANE AND ALUMINUM OXIDE BY DNA COMET ASSAY <i>IN VIVO</i>

The aim of the study was to study the effect of the normotimic drug based on a complex of lithium citrate, polymethylsiloxane and alumina on DNA damage level (DNA comet test) in vivo by alkaline gel electrophoresis. It was shown that at 3 and 18 hours after the drug administration at the highest dose (2000 mg/kg) and therapeutic dose (400 mg/kg), the percentage of DNA in the tail in the cells of the bone marrow does not differ from the negative controls. That may indicate absence of possible carcinogenic action of the lithium-containing drug. On the other hand, the amount of DNA damage in other organs (kidney, liver, large intestine) increased with an exposure time of 3 hours after administration of the drug in a toxic dose. Although, the degree of this effect expression was not high. When the dose was reduced (400 mg/kg) and the duration of the experiment was increased (up to 18 hours), this effect was not detected. That indicates the ability of the drug to enhance DNA damage repair. Given that lithium preparations have a pronounced toxic effect on kidneys, gastrointestinal tract, liver, the increase in the percentage of DNA in the tail in these organs can be a consequence of the cytostatic action of the drug