23 research outputs found

    Polarizabilities and parity non-conservation in the Cs atom and limits on the deviation from the standard electroweak model

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    A semi-empirical calculation of the 6s - 7s Stark amplitude α\alpha in Cs has been performed using the most accurate measurements and calculations of the electromagnetic amplitudes available. This is then used to extract the parameters of the electroweak theory from experimental data. The results are: α=269.0(1.3)a03\alpha = 269.0 (1.3) a_0^3, weak charge of Cs QW=72.41(25)exp(80)theorQ_W = -72.41(25)_{exp} (80)_{theor}, deviation from the Standard model S=1.0(.3)exp(1.0)theorS = -1.0(.3)_{exp} (1.0)_{theor} and limit on the mass of the extra Z-boson in SO(10) model MZx>550GeVM_{Z_x} > 550 GeV.Comment: 8 pages; submitted to Phys. Rev.

    ASIAN TAPEWORM (BOTHRIOCEPHALUS ACHEILOGNATHI) IN NATIVE FISHES FROM THE LITTLE COLORADO RIVER, GRAND CANYON, ARIZONA

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    Volume: 57Start Page: 66End Page: 6

    Building the Partners HealthCare Biobank at Partners Personalized Medicine: Informed Consent, Return of Research Results, Recruitment Lessons and Operational Considerations

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    The Partners HealthCare Biobank is a Partners HealthCare enterprise-wide initiative whose goal is to provide a foundation for the next generation of translational research studies of genotype, environment, gene-environment interaction, biomarker and family history associations with disease phenotypes. The Biobank has leveraged in-person and electronic recruitment methods to enroll >30,000 subjects as of October 2015 at two academic medical centers in Partners HealthCare since launching in 2010. Through a close collaboration with the Partners Human Research Committee, the Biobank has developed a comprehensive informed consent process that addresses key patient concerns, including privacy and the return of research results. Lessons learned include the need for careful consideration of ethical issues, attention to the educational content of electronic media, the importance of patient authentication in electronic informed consent, the need for highly secure IT infrastructure and management of communications and the importance of flexible recruitment modalities and processes dependent on the clinical setting for recruitment

    Implementation of Electronic Consent at a Biobank: An Opportunity for Precision Medicine Research

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    The purpose of this study is to characterize the potential benefits and challenges of electronic informed consent (eIC) as a strategy for rapidly expanding the reach of large biobanks while reducing costs and potentially enhancing participant engagement. The Partners HealthCare Biobank (Partners Biobank) implemented eIC tools and processes to complement traditional recruitment strategies in June 2014. Since then, the Partners Biobank has rigorously collected and tracked a variety of metrics relating to this novel recruitment method. From June 2014 through January 2016, the Partners Biobank sent email invitations to 184,387 patients at Massachusetts General Hospital and Brigham and Women’s Hospital. During the same time period, 7078 patients provided their consent via eIC. The rate of consent of emailed patients was 3.5%, and the rate of consent of patients who log into the eIC website at Partners Biobank was 30%. Banking of biospecimens linked to electronic health records has become a critical element of genomic research and a foundation for the NIH’s Precision Medicine Initiative (PMI). eIC is a feasible and potentially game-changing strategy for these large research studies that depend on patient recruitment
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