Difference in time to result between conventional culture-based method and the Verigene Test.

<p>^a Difference in time between BC-GP or BC-GN result and final culture-based identification and drug susceptibility test results</p><p>^b Only the isolates with concordant results from cultured-based method and the Verigene test were included for the time to result assessment.</p><p>Difference in time to result between conventional culture-based method and the Verigene Test.</p

Resistance gene profile in Gram negative organisms collected in this study.

<p>^a species identified by 16s Sequencing</p><p>Resistance gene profile in Gram negative organisms collected in this study.</p

Performance of BC-GP for identification of Gram positive organisms.

<p>^<i>a</i><i>95% confidence interval was calculated using Adjusted Wald Method (</i><a href="http://www.measuringu.com/wald.htm" target="_blank"><i>http</i>:<i>//www</i>.<i>measuringu</i>.<i>com/wald</i>.<i>htm</i></a>)</p><p>^b Misidentifed as <i>S</i>. <i>pneumoniae</i></p><p>Performance of BC-GP for identification of Gram positive organisms.</p

The overall concordance in bacterial identification between Verigene test and culture-based method in different study sites.

<p>QMH: Queen Mary Hospital; PMH: Princess Margaret Hospital; UCH: United Christian Hospital; PYNEH: Pamela Youde Nethersole Eastern Hospital; 95%CI: 95% confidence interval</p><p>^a 95% confidence interval was calculated using Adjusted Wald Method (<a href="http://www.measuringu.com/wald.htm" target="_blank">http://www.measuringu.com/wald.htm</a>)</p><p>The overall concordance in bacterial identification between Verigene test and culture-based method in different study sites.</p

Performance of Verigene Test in detection of drug resistant organisms.

<p>MRSA: Methicillin resistant <i>Staphylococcus aureus</i>; MRSE: Methicillin resistant <i>Staphylococcus epidermidis;</i> VRE: Vancomycin resistant Enterococcus; ESBL: Extended spectrum beta-lactamase; MDR <i>Acinetobacter</i>: Multidrug resisant <i>Acinetobacter</i></p><p>^a 95% confidence interval was calculated using Adjusted Wald Method (<a href="http://www.measuringu.com/wald.htm" target="_blank">http://www.measuringu.com/wald.htm</a>)</p><p>Performance of Verigene Test in detection of drug resistant organisms.</p

The identities of bacteria in cultures with discordant results reported by culture-based method and the Verigene Test.

<p>^a Organisms are not included in the Verigene Test identification panel</p><p>The identities of bacteria in cultures with discordant results reported by culture-based method and the Verigene Test.</p

Performance of BC-GN for idenifcation of Gram negative organisms.

<p>^a95% confidence interval was calculated using Adjusted Wald Method (<a href="http://www.measuringu.com/wald.htm" target="_blank">http://www.measuringu.com/wald.htm</a>)</p><p>^b Species were confirmed by 16s rRNA sequencing</p><p>^c Misidentified as <i>Enterobacter spp</i>. by BC-GN</p><p>^d Seven isolates were confirmed to be <i>K</i>. <i>variicola</i> instead of <i>K</i>. <i>pneumoniae</i>by 16s rRNA and yGGEsequencing. After the discrepancy resolution, the sensitivity for <i>K</i>. <i>pneumoniae</i> was raised to 80% (36/45).</p><p>^e One was misidentified as mixed culture of <i>K</i>. <i>pneumoniae</i> and <i>K</i>. <i>oxytoca</i> whereas the other one was misidentified as mixed cultured of <i>K</i>. <i>pneumoniae</i> and <i>Enterobacter</i></p><p>^f Misidentified as <i>K</i>. <i>oxytoca</i></p><p>Performance of BC-GN for idenifcation of Gram negative organisms.</p