118 research outputs found
Assessment of bystander killing-mediated therapy of malignant brain tumors using a multimodal imaging approach
Randomized controlled trial of postoperative exercise rehabilitation program after lumbar spine fusion: study protocol
Abstract
Background
Lumbar spine fusion (LSF) effectively decreases pain and disability in specific spinal disorders; however, the disability rate following surgery remains high. This, combined with the fact that in Western countries the number of LSF surgeries is increasing rapidly it is important to develop rehabilitation interventions that improve outcomes.
Methods/design
In the present RCT-study we aim to assess the effectiveness of a combined back-specific and aerobic exercise intervention for patients after LSF surgery. One hundred patients will be randomly allocated to a 12-month exercise intervention arm or a usual care arm. The exercise intervention will start three months after surgery and consist of six individual guidance sessions with a physiotherapist and a home-based exercise program. The primary outcome measures are low back pain, lower extremity pain, disability and quality of life. Secondary outcomes are back function and kinesiophobia. Exercise adherence will also be evaluated. The outcome measurements will be assessed at baseline (3 months postoperatively), at the end of the exercise intervention period (15 months postoperatively), and after a 1-year follow-up.
Discussion
The present RCT will evaluate the effectiveness of a long-term rehabilitation program after LSF. To our knowledge this will be the first study to evaluate a combination of strength training, control of the neutral lumbar spine position and aerobic training principles in rehabilitation after LSF.
Trial registration
ClinicalTrials.gov Identifier NCT00834015peerReviewe
Resektion rezidivierender pertoclivaler Meningeome - Berechtigen die Ergebnisse eine wiederholte Operation?
Clinical impact of TERT promoter mutation detection in cell-free DNA of patients with IDH wild-type glioblastomas - a pilot prospective study
Outcome nach Behandlung von Patienten mit primären und sekundären anaplastischen Meningeomen
Retrospektive Analyse von Patienten mit spontaner intrakranieller Hypotension nach Blutpatch-Therapie
IDH1 and IDH2 mutations and their role in progression of low grade and malignant gliomas
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