Genome Sequence of Stenotrophomonas maltophilia PML168, Which Displays Baeyer-Villiger Monooxygenase Activity

Stenotrophomonas maltophilia PML168 was isolated from Wembury Beach on the English Coast from a rock pool following growth and selection on agar plates. Here we present the permanent draft genome sequence, which has allowed prediction of function for several genes encoding enzymes relevant to industrial biotechnology, including a novel flavoprotein monooxygenase

Integrated production system optimization using global optimization techniques

Many optimization problems related to integrated oil and gas production systems are nonconvex and multimodal. Additionally, apart from the innate nonsmoothness of many optimization problems, nonsmooth functions such as minimum and maximum functions may be used to model flow/pressure controllers and cascade mass in the gas gathering and blending networks. In this paper we study the application of different versions of the derivative free Discrete Gradient Method (DGM) as well as the Lipschitz Global Optimizer (LGO) suite to production optimization in integrated oil and gas production systems and their comparison with various local and global solvers used with the General Algebraic Modeling System (GAMS). Four nonconvex and nonsmooth test cases were constructed from a small but realistic integrated gas production system optimization problem. The derivation of the system of equations for the various test cases is also presented. Results demonstrate that DGM is especially effective for solving nonsmooth optimization problems and its two versions are capable global optimization algorithms. We also demonstrate that LGO solves successfully the presented test (as well as other related real-world) problems.C

Correcting for non-periodic behaviour in perturbative experiments: application to heat pulse propagation and modulated gas-puff experiments

This paper introduces a recent innovation in dealing with non-periodic behavior often referred to as transients. These transients can be the result from unforced response due to the initial condition and other drifts which are a source of error when performing and interpreting Fourier analysis on measurement data. Fourier analysis is particularly relevant in system identification used to build feedback controllers and the analysis of various pulsed experiments such as heat pulse propagation studies. The basic idea behind the methodology is that transients are continuous complex-valued smooth functions in the Fourier domain which can be estimated from the Fourier data. Then, these smooth functions can be approximately subtracted from the data such that only periodic components are retained. The merit of the approach is shown in two experimental examples, i.e., heat pulse propagation (core transport analysis) and radiation front movement due to gas puffing. The examples show that the quality of the data is significantly improved such that it allows new interpretation of the results even for non-ideal measurements.</p