17,598 research outputs found
CP Asymmetry in Charged Higgs Decays to Chargino-Neutralino
We analyze the charge-parity (CP) asymmetry in the charged Higgs boson decays
to chargino-neutralino pairs, H^- -> chargino_i + neutralino_j. We show first
that these modes have a large branching ratio for m_H^- > 600 GeV. We use
Cutkosky rules to obtain the analytical formulas needed for the evaluation of
the asymmetry under consideration. We then calculate the CP asymmetry in
chargino-neutralino decays by including supersymmetric mass bounds, as well as
constraints from b -> s gamma, (g-2)_mu, Delta\rho and electric dipole moments.
Finally, we discuss observability of the asymmetry at the LHC by calculating
the number of required charged Higgs events to observe the asymmetry for each
decay channel. We show that the inclusion of constraints considerably reduces
the projected CP asymmetry, and that the optimal channel for observing the
asymmetry is H^- -> chargino_1 + neutralino_2.Comment: 23 pages, 8 figures, one tabl
Multi-function based modeling of 3D heterogeneous wound scaffolds for improved wound healing
This paper presents a new multi-function based modeling of 3D heterogeneous porous wound scaffolds to improve wound healing process for complex deep acute or chronic wounds. An imaging-based approach is developed to extract 3D wound geometry and recognize wound features. Linear healing fashion of the wound margin towards the wound center is mimicked. Blending process is thus applied to the extracted geometry to partition the scaffold into a number of uniformly gradient healing regions. Computer models of 3D engineered porous wound scaffolds are then developed for solid freeform modeling and fabrication. Spatial variation over biomaterial and loaded bio-molecule concentration is developed based on wound healing requirements. Release of bio-molecules over the uniform healing regions is controlled by varying their amount and entrapping biomaterial concentration. Thus, localized controlled release is developed to improve wound healing. A prototype multi-syringe single nozzle deposition system is used to fabricate a sample scaffold. Proposed methodology is implemented and illustrative examples are presented in this paper
3D hybrid wound devices for spatiotemporally controlled release kinetics
This paper presents localized and temporal control of releasekinetics over 3-dimensional (3D) hybridwounddevices to improve wound-healing process. Imaging study is performed to extract wound bed geometry in 3D. Non-Uniform Rational B-Splines (NURBS) based surface lofting is applied to generate functionally graded regions. Diffusion-based releasekinetics model is developed to predict time-based release of loaded modifiers for functionally graded regions. Multi-chamber single nozzle solid freeform dispensing system is used to fabricate wounddevices with controlled dispensing concentration. Spatiotemporal control of biological modifiers thus enables a way to achieve target delivery to improve wound healing
Optimized normal and distance matching for heterogeneous object modeling
This paper presents a new optimization methodology of material blending for heterogeneous object modeling by matching the material governing features for designing a heterogeneous object. The proposed method establishes point-to-point correspondence represented by a set of connecting lines between two material directrices. To blend the material features between the directrices, a heuristic optimization method developed with the objective is to maximize the sum of the inner products of the unit normals at the end points of the connecting lines and minimize the sum of the lengths of connecting lines. The geometric features with material information are matched to generate non-self-intersecting and non-twisted connecting surfaces. By subdividing the connecting lines into equal number of segments, a series of intermediate piecewise curves are generated to represent the material metamorphosis between the governing material features. Alternatively, a dynamic programming approach developed in our earlier work is presented for comparison purposes. Result and computational efficiency of the proposed heuristic method is also compared with earlier techniques in the literature. Computer interface implementation and illustrative examples are also presented in this paper
Designing heterogeneous porous tissue scaffolds for additive manufacturing processes
A novel tissue scaffold design technique has been proposed with controllable heterogeneous architecture design suitable for additive manufacturing processes. The proposed layer-based design uses a bi-layer pattern of radial and spiral layers consecutively to generate functionally gradient porosity, which follows the geometry of the scaffold. The proposed approach constructs the medial region from the medial axis of each corresponding layer, which represents the geometric internal feature or the spine. The radial layers of the scaffold are then generated by connecting the boundaries of the medial region and the layer's outer contour. To avoid the twisting of the internal channels, reorientation and relaxation techniques are introduced to establish the point matching of ruling lines. An optimization algorithm is developed to construct sub-regions from these ruling lines. Gradient porosity is changed between the medial region and the layer's outer contour. Iso-porosity regions are determined by dividing the subregions peripherally into pore cells and consecutive iso-porosity curves are generated using the isopoints from those pore cells. The combination of consecutive layers generates the pore cells with desired pore sizes. To ensure the fabrication of the designed scaffolds, the generated contours are optimized for a continuous, interconnected, and smooth deposition path-planning. A continuous zig-zag pattern deposition path crossing through the medial region is used for the initial layer and a biarc fitted isoporosity curve is generated for the consecutive layer with C-1 continuity. The proposed methodologies can generate the structure with gradient (linear or non-linear), variational or constant porosity that can provide localized control of variational porosity along the scaffold architecture. The designed porous structures can be fabricated using additive manufacturing processes
Modeling of multifunctional porous tissue scaffolds with continuous deposition path plan
A novel modeling technique for porous tissue scaffolds with targeting the functionally gradient variational porosity with continuous material deposition planning has been proposed. To vary the porosity of the designed scaffold
functionally, medial axis transformation is used. The medial axis of each layers of the scaffold is calculated and used as an internal feature. The medial axis is then used connected to the outer contour using an optimum matching. The desired pore size and hence the porosity have been achieved by discretizing the sub-regions along its peripheral direction based on the pore
size while meeting the tissue scaffold design constraints. This would ensure the truly porous nature of the structure in every direction as well as controllable porosity with interconnected pores. Thus the desired controlled variational porosity along the scaffold architecture has been achieved with the combination of two geometrically oriented consecutive layers. A continuous,
interconnected and optimized tool-path has been generated for successive layers for additive-manufacturing or solid free form fabrication process. The proposed methodology has been computationally implemented with illustrative examples.
Furthermore, the designed example scaffolds with the desired pore size and porosity has been fabricated with an extrusion based bio-fabrication process
Weak Isospin Violations in Charged and Neutral Higgs Couplings from SUSY Loop Corrections
Supersymmetric QCD and supersymmetric electroweak loop corrections to the
violations of weak isospin to Yukawa couplings are investigated. Specifically
it involves an analysis of the supersymmetric loop corrections to the Higgs
couplings to the third generation quarks and leptons. Here we analyze the SUSY
loop corrections to the charged Higgs couplings which are then compared with
the supersymmetric loop corrections to the neutral Higgs couplings previously
computed. It is found that the weak isospin violations can be quite
significant, i.e, as much as 40-50% or more of the total loop correction to the
Yukawa coupling. The effects of CP phases are also studied and it is found that
these effects can either enhance or suppress the weak isospin violations. We
also investigate the weak isospin violation effects on the branching ratio
and show that the effects
are sensitive to CP phases. Thus an accurate measurement of this branching
ratio along with the branching ratio of the neutral Higgs boson decays can
provide a measure of weak isospin violation along with providing a clue to the
presence of supersymmetry.Comment: 20 pages, 9 figure
Large evolution of the bilinear Higgs coupling parameter in SUSY models and reduction of phase sensitivity
The phases in a generic low-energy supersymmetric model are severely
constrained by the experimental upper bounds on the electric dipole moments of
the electron and the neutron. Coupled with the requirement of radiative
electroweak symmetry breaking, this results in a large degree of fine tuning of
the phase parameters at the unification scale. In supergravity type models,
this corresponds to very highly tuned values for the phases of the bilinear
Higgs coupling parameter and the universal trilinear coupling . We
identify a cancellation/enhancement mechanism associated with the
renormalization group evolution of , which, in turn, reduces such
fine-tuning quite appreciably without taking recourse to very large masses for
the supersymmetric partners. We find a significant amount of reduction of this
fine-tuning in nonuniversal gaugino mass models that do not introduce any new
phases.Comment: Version to appear in Phys.Rev.D. Insignificant changes like a few
typos corrected. 26 pages, 7 figures, LaTe
On the EDM Cancellations in D-brane models
We analyze the possibility of simultaneous electron, neutron, and mercury
electric dipole moment (EDM) cancellations in the mSUGRA and D--brane models.
We find that the mercury EDM constraint practically rules out the cancellation
scenario in D-brane models whereas in the context of mSUGRA it is still allowed
with some fine-tuning.Comment: 10 pages, to appear in Phys. Rev. Let
One-loop Neutron Electric Dipole Moment from Supersymmetry without R-parity
We present a detailed analysis together with exact numerical calculations on
one-loop contributions to neutron electric dipole moment from supersymmetry
without R-parity, focusing on the gluino, chargino, and neutralino
contributions. Apart from the neglected family mixing among quarks, complete
formulae are given for the various contributions, through the quark dipole
operators, to which the present study is restricted. We discuss the structure
and main features of the R-parity violating contributions and the interplay
between the R-parity conserving and violating parameters. In particular, the
parameter combination , under the optimal
parametrization adopted, is shown to be solely responsible for the R-parity
violating contributions in the supersymmetric loop diagrams. While
could bear a complex phase, the latter is not
necessary to have a R-parity violating contribution.Comment: 43 pages Revtex with 15 eps- and 4 ps- figure files incoporated;
proofread version to be published in Phys. Rev.
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