186 research outputs found

    COASTLINE ZONE EXTRACTION USING LANDSAT-8 OLI IMAGERY, CASE STUDY: BODRUM PENINSULA, TURKEY

    Get PDF
    Coastline extraction is a fundamental work for coastal resource management and coastal environmental protection. Today, by using digital image processing techniques, coastline extraction can be done with remote sensing imagery systems. In this study, Landsat 8 Operational Land Imagery (OLI) data have been the main data source due to free access and sufficient spatial resolution for coast line extraction. This research is focused on determining the coastline length and measuring land area by using Landsat 8 OLI satellite image for Bodrum Peninsula, Turkey. Three commonly used methods have been applied in order to determine sea-land boundary line and its length, and area of the study area. The Automatic Water Extraction Index (AWEI), Iterative Self-Organizing Data Analysis Technique (ISODATA) unsupervised classification technique and on screen digitizing method was chosen for identification of coastal boundaries. Results of coastline length and land areas of Bodrum by using AWEI, ISODATA and on-screen digitizing are compared with each other. This study shows that with using optimal threshold value, AWEI can be used for coast line extraction method with coherently for Landsat 8 OLI satellite imagery. The overall results show that coastline extraction from satellite imagery can be done with sufficient accuracy using spectral water indices instead of time consuming on-screen digitizing

    Heterogeneity of pollen food allergy syndrome in seven Southern European countries: The @IT.2020 multicenter study

    Get PDF
    Background Pollen food allergy syndrome (PFAS) is a frequently underdiagnosed disease due to diverse triggers, clinical presentations, and test results. This is especially relevant in geographic areas with a broad spectrum of pollen sensitization, such as Southern Europe. Objectives To elucidate similarities and differences of PFAS in nine Southern European centers and identify associated characteristics and unique markers of PFAS. Methods As part of the @IT.2020 Multicenter Study, 815 patients with seasonal allergic rhinitis (SAR), aged 10-60 years, were recruited in seven countries. They completed questionnaires regarding SAR, comorbidities, family history, and PFAS, and underwent skin prick testing (SPT) and serum IgE testing. Results Of the 815 patients, 167 (20.5%) reported PFAS reactions. Most commonly, eliciting foods were kiwi (58, 34.7%), peach (43, 25.7%), and melon (26, 15.6%). Reported reactions were mostly local (216/319, 67.7%), occurring within 5 min of contact with elicitors (209/319, 65.5%). Associated characteristics included positive IgE to at least one panallergen (profilin, PR-10, or nsLTP) (p = 0.007), maternal PFAS (OR: 3.716, p = 0.026), and asthma (OR: 1.752, p = 0.073). Between centers, heterogeneity in prevalence (Marseille: 7.5% vs. Rome: 41.4%, p < 0.001) and of clinical characteristics was apparent. Cypress played a limited role, with only 1/22 SPT mono-sensitized patients reporting a food reaction (p < 0.073). Conclusions PFAS is a frequent comorbidity in Southern European SAR patients. Significant heterogeneity of clinical characteristics in PFAS patients among the centers was observed and may be related to the different pollen sensitization patterns in each geographic area. IgE to panallergen(s), maternal PFAS, and asthma could be PFAS-associated characteristics

    Ramucirumab plus erlotinib in patients with untreated, EGFR-mutated, advanced non-small-cell lung cancer (RELAY): a randomised, double-blind, placebo-controlled, phase 3 trial

    Get PDF

    Cardiac disease in patients with mucopolysaccharidosis: presentation, diagnosis and management

    Get PDF
    The mucopolysaccharidoses (MPSs) are inherited lysosomal storage disorders caused by the absence of functional enzymes that contribute to the degradation of glycosaminoglycans (GAGs). The progressive systemic deposition of GAGs results in multi-organ system dysfunction that varies with the particular GAG deposited and the specific enzyme mutation(s) present. Cardiac involvement has been reported in all MPS syndromes and is a common and early feature, particularly for those with MPS I, II, and VI. Cardiac valve thickening, dysfunction (more severe for left-sided than for right-sided valves), and hypertrophy are commonly present; conduction abnormalities, coronary artery and other vascular involvement may also occur. Cardiac disease emerges silently and contributes significantly to early mortality
    corecore