7,740 research outputs found
A question of time: tissue adaptation to mechanical forces.
While much attention has been focused on the force-generating mechanisms responsible for shaping developing embryos, less is known about the ways in which cells in animal tissues respond to mechanical stimuli. Forces will arise within a tissue as the result of processes such as local cell death, growth and division, but they can also be an indirect consequence of morphogenetic movements in neighbouring tissues or be imposed from the outside, for example, by gravity. If not dealt with, the accumulation of stress and the resulting tissue deformation can pose a threat to tissue integrity and structure. Here we follow the time-course of events by which cells and tissues return to their preferred state following a mechanical perturbation. In doing so, we discuss the spectrum of biological and physical mechanisms known to underlie mechanical homeostasis in animal tissues
Handwritten digit recognition by bio-inspired hierarchical networks
The human brain processes information showing learning and prediction
abilities but the underlying neuronal mechanisms still remain unknown.
Recently, many studies prove that neuronal networks are able of both
generalizations and associations of sensory inputs. In this paper, following a
set of neurophysiological evidences, we propose a learning framework with a
strong biological plausibility that mimics prominent functions of cortical
circuitries. We developed the Inductive Conceptual Network (ICN), that is a
hierarchical bio-inspired network, able to learn invariant patterns by
Variable-order Markov Models implemented in its nodes. The outputs of the
top-most node of ICN hierarchy, representing the highest input generalization,
allow for automatic classification of inputs. We found that the ICN clusterized
MNIST images with an error of 5.73% and USPS images with an error of 12.56%
The inner kiloparsec of the jet in 3C264
We present new multi-frequency EVN, MERLIN and VLA observations of the radio
source 3C264, sensitive to linear scales ranging from the parsec to several
kiloparsecs. The observations confirm the existence of regions with different
properties in the first kiloparsec of the jet. The most remarkable feature is
the transition between a well collimated narrow jet at distances from the core
below 80 pc, to a conical-shaped wide jet, with an opening angle of 20 degrees.
Another change of properties, consisting of an apparent deflection of the jet
ridge line and a diminution of the surface brightness, occurs at a distance of
300 pc from the core, coincident with the radius of a ring observed at optical
wavelengths. Our observations add new pieces of information on the spectrum of
the radio-optical jet of 3C264, with results consistent with a synchrotron
emission mechanism and a spectrum break frequency in the infrared. Brightness
profiles taken perpendicularly to the jet of 3C264 are consistent with a spine
brightened jet at distances below 100 pc from the core, and an edge-brightened
jet beyond, which can be interpreted as evidence of a transverse jet velocity
structure. Our observations do not allow us to distinguish between the presence
of a face--on dust and gas disk at the center of the host galaxy of 3C264, or
rather an evacuated bubble. However, the properties of the jet structure, the
changes in the polarization angle, and the plausible jet orientation can be
naturally brought into agreement in the bubble scenario.Comment: 10 pages, 9 figures, accepted in A&
The Emergence of the Modern Universe: Tracing the Cosmic Web
This is the report of the Ultraviolet-Optical Working Group (UVOWG)
commissioned by NASA to study the scientific rationale for new missions in
ultraviolet/optical space astronomy approximately ten years from now, when the
Hubble Space Telescope (HST) is de-orbited. The UVOWG focused on a scientific
theme, The Emergence of the Modern Universe, the period from redshifts z = 3 to
0, occupying over 80% of cosmic time and beginning after the first galaxies,
quasars, and stars emerged into their present form. We considered
high-throughput UV spectroscopy (10-50x throughput of HST/COS) and wide-field
optical imaging (at least 10 arcmin square). The exciting science to be
addressed in the post-HST era includes studies of dark matter and baryons, the
origin and evolution of the elements, and the major construction phase of
galaxies and quasars. Key unanswered questions include: Where is the rest of
the unseen universe? What is the interplay of the dark and luminous universe?
How did the IGM collapse to form the galaxies and clusters? When were galaxies,
clusters, and stellar populations assembled into their current form? What is
the history of star formation and chemical evolution? Are massive black holes a
natural part of most galaxies? A large-aperture UV/O telescope in space
(ST-2010) will provide a major facility in the 21st century for solving these
scientific problems. The UVOWG recommends that the first mission be a 4m
aperture, SIRTF-class mission that focuses on UV spectroscopy and wide-field
imaging. In the coming decade, NASA should investigate the feasibility of an 8m
telescope, by 2010, with deployable optics similar to NGST. No high-throughput
UV/Optical mission will be possible without significant NASA investments in
technology, including UV detectors, gratings, mirrors, and imagers.Comment: Report of UV/O Working Group to NASA, 72 pages, 13 figures, Full
document with postscript figures available at
http://casa.colorado.edu/~uvconf/UVOWG.htm
Scale Dependence of Polarized DIS Asymmetries
We compare the dependence of the polarized deep inelastic scattering
proton asymmetry, driven by the leading order Altarelli Parisi evolution
equations, to those arising from fixed order and
approximations. It is shown that the evolution effects associated with gluons,
which are not properly taken into account by the leading order approximation,
cannot be neglected in the analysis of the most recent experimental data.Comment: Latex file, (9 figures in postcript available from
[email protected]
- …