Non-intrusive tunable resonant microwave cavity for optical detected magnetic resonance of NV centres in nanodiamonds

Optically detected magnetic resonance (ODMR) in nanodiamond nitrogen-vacancy (NV) centres is usually achieved by applying a microwave field delivered by micron-size wires, strips or antennas directly positioned in very close proximity (∼ μm) of the nanodiamond crystals. The microwave field couples evanescently with the ground state spin transition of the NV centre (2.87 GHz at zero magnetic field), which results in a reduction of the centre photoluminescence. We propose an alternative approach based on the construction of a dielectric resonator. We show that such a resonator allows for the efficient detection of NV spins in nanodiamonds without the constraints associated to the laborious positioning of the microwave antenna next to the nanodiamonds, providing therefore improved flexibility. The resonator is based on a tunable Transverse Electric Mode in a dielectric-loaded cavity, and we demonstrate that the resonator can detect single NV centre spins in nanodiamonds using less microwave power than alternative techniques in a non-intrusive manner. This method can achieve higher precision measurement of ODMR of paramagnetic defects spin transition in the micro to millimetre-wave frequency domain. Our approach would permit the tracking of NV centres in biological solutions rather than simply on the surface, which is desirable in light of the recently proposed applications of using nanodiamonds containing NV centres for spin labelling in biological systems with single spin and single particle resolution. © 2013 Copyright SPIE

The Fourth Positive System of Carbon Monoxide in the Hubble Space Telescope Spectra of Comets

The rich structure of the Fourth Positive System (A-X) of carbon monoxide accounts for many of the spectral features seen in long slit HST-STIS observations of comets 153P/Ikeya-Zhang, C/2001 Q4 (NEAT), and C/2000 WM1 (LINEAR), as well as in the HST-GHRS spectrum of comet C/1996 B2 Hyakutake. A detailed CO fluorescence model is developed to derive the CO abundances in these comets by simultaneously fitting all of the observed A-X bands. The model includes the latest values for the oscillator strengths and state parameters, and accounts for optical depth effects due to line overlap and self-absorption. The model fits yield radial profiles of CO column density that are consistent with a predominantly native source for all the comets observed by STIS. The derived CO abundances relative to water in these comets span a wide range, from 0.44% for C/2000 WM1 (LINEAR), 7.2% for 153P/Ikeya-Zhang, 8.8% for C/2001 Q4 (NEAT) to 20.9% for C/1996 B2 (Hyakutake). The subtraction of the CO spectral features using this model leads to the first identification of a molecular hydrogen line pumped by solar HI Lyman-beta longward of 1200A in the spectrum of comet 153P/Ikeya-Zhang. (Abridged)Comment: 12 pages, 11 figures, ApJ accepte

Absorbing boundary conditions for the Westervelt equation

The focus of this work is on the construction of a family of nonlinear absorbing boundary conditions for the Westervelt equation in one and two space dimensions. The principal ingredient used in the design of such conditions is pseudo-differential calculus. This approach enables to develop high order boundary conditions in a consistent way which are typically more accurate than their low order analogs. Under the hypothesis of small initial data, we establish local well-posedness for the Westervelt equation with the absorbing boundary conditions. The performed numerical experiments illustrate the efficiency of the proposed boundary conditions for different regimes of wave propagation

Addressing a single NV−^{-} spin with a macroscopic dielectric microwave cavity

We present a technique for addressing single NV$^{-}$ center spins in diamond over macroscopic distances using a tunable dielectric microwave cavity. We demonstrate optically detected magnetic resonance (ODMR) for a single NV$^{-}$ center in a nanodiamond (ND) located directly under the macroscopic microwave cavity. By moving the cavity relative to the ND, we record the ODMR signal as a function of position, mapping out the distribution of the cavity magnetic field along one axis. In addition, we argue that our system could be used to determine the orientation of the NV$^{-}$ major axis in a straightforward manner

Numerical model for simulation of blood microcirculation and study of sickle cell disease

Thesis (Ph. D.)--Massachusetts Institute of Technology, Dept. of Aeronautics and Astronautics, 2010.Cataloged from PDF version of thesis.Includes bibliographical references (p. 214-226).Sickle cell disease is nowadays one of the most challenging blood diseases, where patients suffer from both chronic and acute episodes of painful medical conditions. In particular, unpredictable crises due to blood vessel occlusion remain one of the least understood stages of the disease, which focuses the attention of medical research. A novel methodology has been developed to address sickle cell disease, based on highly descriptive mathematical models for blood flow in the capillaries. The main focus of our original sickle cell model is the coupling between oxygen delivery and red blood cell dynamics, which is crucial to understanding sickle cell crises and is unique to this blood disease. Based on an original physical description of polymerizing sickle hemoglobin (HbS), an extensive study of blood dynamics was initiated through simulations of red cells deforming within the capillary vessels. Our investigations relied on the use of a large mathematical system of equations describing oxygen transfer, blood plasma dynamics and red cell membrane mechanics. Abnormal dynamics were characterized in terms of resistance to blood flow (apparent viscosity), and oxygen delivery performance. The results presented in this thesis describe successfully qualitative and quantitative aspects of blood dynamics preceding sickle cell crises, through a detailed comparison of normal blood with sickle cell blood. Potential therapeutical directions were successfully identified, and assessed through simulations and systematic analysis of our results. This research is expected to spur the development of innovative strategies to study sickle cell disease, and also raise interest in other related fields of blood research, promoting analysis-driven development of new therapeutical directions.by François Thomas Le Floch-Yin.Ph.D