Concurrent Multi-Target Tracking

Simulation89 is an emulation of various SDI tasks (tracking, engagement management and ‘look ahead’) developed for the U. S. Air Force. The simulation presently deals with the boost, post-boost and early midcourse phases of a ’mass raid’ scenario, and is designed to process scenarios with a few thousand targets. The simulation is run on the Mark-III hypercube, with individual tasks performed on subcubes of the full hypercube. In general, the computations within individual subcubes are done in a synchronous manner (i.e., CrOS), while communications between tasks/subcubes are done asynchronously

Computational and Theoretical Aspects of a Grain-Boundary Model at Finite Deformations

A model to describe the role of grain boundaries in the overall response of a polycrystalline material at small length scales subject to finite deformations is presented. Three alternative thermodynamically consistent plastic flow relations on the grain boundary are derived and compared using a series of numerical experiments. The numerical model is obtained by approximating the governing relations using the finite element method. In addition, the infinitesimal and finite deformation theories are compared, and the limitations of the former made clear

Territorial Tactics: The Socio-spatial Significance of Private Policing Strategies in Cape Town

This paper analyses the policing strategies of private security companies operating in urban space. An existing literature has considered the variety of ways that territory becomes of fundamental importance in the work of public police forces. However, this paper examines territory in the context of private security companies. Drawing on empirical research in Cape Town, it examines how demarcated territories become key subjects in private policing. Private security companies are responsible for a relatively small section of the city, while in contrast the public police ultimately have to see city space as a whole. Hence, private policing strategy becomes one of displacement, especially of so-called undesirables yielding a patchworked public space associated with private enclaves of consumption. The conclusions signal the historical resonances and comparative implications of these political-legal-security dynamics. © 2013 Urban Studies Journal Limited

Changes in specific metabolic pathways are essential steps in the early apoptotic process in the liver

the immunosuppressant Cyclosporine A (CsA), we used multinuclear NMR spectroscopy and molecular studies to characterize metabolic pathways in mice liver during anti-Fas-induced apoptosis. An upregulation of specific metabolic pathways of glucose was the earliest indicator of the effect of Fas on the liver. CsA prevented apoptosis and energy failure at late stages, while the reversal of Fas-induced metabolic upregulation at early stages preceded the protective effect of EGF on programmed cell death. These phenomena provide useful hints for the understanding of early mechanisms controlling apoptotic cell death

Single-Top-Quark Production via W-Gluon Fusion at Next-to-Leading Order

Single-top-quark production via W-gluon fusion at hadron colliders provides an opportunity to directly probe the charged-current interaction of the top quark. We calculate the next-to-leading-order corrections to this process at the Fermilab Tevatron, the CERN Large Hadron Collider, and DESY HERA. Using a b-quark distribution function to sum collinear logarithms, we show that there are two independent corrections, of order 1/[ln(m_t^2/m_b^2)] and alpha_s. This observation is generic to processes involving a perturbatively derived heavy-quark distribution function at an energy scale large compared with the heavy-quark mass.Comment: 19 pages, 9 figures, small update to Phys. Rev. D versio

Polyclonal Aptamer Libraries from a FluRoot-SELEX for the Specific Labeling of the Apical and Elongation/Differentiation Zones of Arabidopsis thaliana Roots

In more than 30 years of aptamer research, it has become widely accepted that aptamers are fascinating binding molecules for a vast variety of applications. However, the majority of targets have been proteins, although special variants of the so-called SELEX process for the molecular evolution of specific aptamers have also been developed, allowing for the targeting of small molecules as well as larger structures such as cells and even cellular networks of human (tumor) tissues. Although the provocative thesis is widely accepted in the field, that is, in principle, any level of complexity for SELEX targets is possible, the number of studies on whole organs or at least parts of them is limited. To pioneer this thesis, and based on our FluCell-SELEX process, here, we have developed polyclonal aptamer libraries against apices and the elongation/differentiation zones of plant roots as examples of organs. We show that dedicated libraries can specifically label the respective parts of the root, allowing us to distinguish them in fluorescence microscopy. We consider this achievement to be an initial but important evidence for the robustness of this SELEX variant. These libraries may be valuable tools for plant research and a promising starting point for the isolation of more specific individual aptamers directed against root-specific epitopes

Stratified spatiotemporal chaos in anisotropic reaction-diffusion systems

Numerical simulations of two dimensional pattern formation in an anisotropic bistable reaction-diffusion medium reveal a new dynamical state, stratified spatiotemporal chaos, characterized by strong correlations along one of the principal axes. Equations that describe the dependence of front motion on the angle illustrate the mechanism leading to stratified chaos