Volumetric calibration of a propellant utilization system

Method of calibrating capacitance-type propellant mass sensors provides meaningful mass units accurate to within one percent of the total load. Neither special propellant loading nor test firing is required. Recalibration of the system is possible without special propellant loading. This method provides increased flexibility for vehicle operation

Non-destructive Phenotyping of Lettuce Plants in Early Stages of Development with Optical Sensors

Rapid development of plants is important for the production of 'baby-leaf' lettuce that is harvested when plants reach the four- to eight-leaf stage of growth. However, environmental factors, such as high or low temperature, or elevated concentrations of salt, inhibit lettuce growth. Therefore, non-destructive evaluations of plants can provide valuable information to breeders and growers. The objective of the present study was to test the feasibility of using non-destructive phenotyping with optical sensors for the evaluations of lettuce plants in early stages of development. We performed the series of experiments to determine if hyperspectral imaging and chlorophyll fluorescence imaging can determine phenotypic changes manifested on lettuce plants subjected to the extreme temperature and salinity stress treatments. Our results indicate that top view optical sensors alone can accurately determine plant size to approximately 7 g fresh weight. Hyperspectral imaging analysis was able to detect changes in the total chlorophyll (RCC) and anthocyanin (RAC) content, while chlorophyll fluorescence imaging revealed photoinhibition and reduction of plant growth caused by the extreme growing temperatures (3 and 39°C) and salinity (100 mM NaCl). Though no significant correlation was found between Fv/Fm and decrease in plant growth due to stress when comparisons were made across multiple accessions, our results indicate that lettuce plants have a high adaptability to both low (3°C) and high (39°C) temperatures, with no permanent damage to photosynthetic apparatus and fast recovery of plants after moving them to the optimal (21°C) temperature. We have also detected a strong relationship between visual rating of the green- and red-leaf color intensity and RCC and RAC, respectively. Differences in RAC among accessions suggest that the selection for intense red color may be easier to perform at somewhat lower than the optimal temperature. This study serves as a proof of concept that optical sensors can be successfully used as tools for breeders when evaluating young lettuce plants. Moreover, we were able to identify the locus for light green leaf color (qLG4), and position this locus on the molecular linkage map of lettuce, which shows that these techniques have sufficient resolution to be used in a genetic context in lettuce.IS acknowledges the receipt of a fellowship from the OECD Co-operative Research Programme: Biological Resource Management for Sustainable Agricultural Systems in 2013

Creating Open Digital Library Using XML: Implementation of OAi-PMH Protocol at CERN

This article describes the implementation of the OAi-PMH protocol within the CERN Document Server (CDS). In terms of the protocol, CERN acts both as a data provider and service provider and the two core applications are described. The application of XML Schema and XSLT technology is emphasized

A novel design process of low cost 3D printed ambidextrous finger designed for an ambidextrous robotic hand

This paper presents the novel mechanical design of an ambidextrous finger specifically designed for an ambidextrous anthropomorphic robotic hand actuated by pneumatic artificial muscles. The ambidextrous nature of design allows fingers to perform both left and right hand movements. The aim of our design is to reduce the number of actuators, increase the range of movements with best possible range ideally greater than a common human finger. Four prototypes are discussed in this paper; first prototype is focused on the choice of material and to consider the possible ways to reduce friction. Second prototype is designed to investigate the tendons routing configurations. Aim of third and fourth prototype is to improve the overall performance and to maximize the grasping force. Finally, a unified design (Final design) is presented in great detail. Comparison of all prototypes is done from different angles to evaluate the best design. The kinematic features of intermediate mode have been analysed to optimize both the flexibility and the robustness of the system, as well as to minimize the number of pneumatic muscles. The final design of an ambidextrous finger has developed, tested and 3D printed

Widespread Partisan Gerrymandering Mostly Cancels Nationally, but Reduces Electoral Competition

Congressional district lines in many U.S. states are drawn by partisan actors, raising concerns about gerrymandering. To separate the partisan effects of redistricting from the effects of other factors including geography and redistricting rules, we compare possible party compositions of the U.S. House under the enacted plan to those under a set of alternative simulated plans that serve as a non-partisan baseline. We find that partisan gerrymandering is widespread in the 2020 redistricting cycle, but most of the electoral bias it creates cancels at the national level, giving Republicans two additional seats on average. Geography and redistricting rules separately contribute a moderate pro-Republican bias. Finally, we find that partisan gerrymandering reduces electoral competition and makes the partisan composition of the U.S. House less responsive to shifts in the national vote.Comment: 10 pages, 4 figures, plus references and appendi

Evaluating Bias and Noise Induced by the U.S. Census Bureau's Privacy Protection Methods

The United States Census Bureau faces a difficult trade-off between the accuracy of Census statistics and the protection of individual information. We conduct the first independent evaluation of bias and noise induced by the Bureau's two main disclosure avoidance systems: the TopDown algorithm employed for the 2020 Census and the swapping algorithm implemented for the 1990, 2000, and 2010 Censuses. Our evaluation leverages the recent release of the Noisy Measure File (NMF) as well as the availability of two independent runs of the TopDown algorithm applied to the 2010 decennial Census. We find that the NMF contains too much noise to be directly useful alone, especially for Hispanic and multiracial populations. TopDown's post-processing dramatically reduces the NMF noise and produces similarly accurate data to swapping in terms of bias and noise. These patterns hold across census geographies with varying population sizes and racial diversity. While the estimated errors for both TopDown and swapping are generally no larger than other sources of Census error, they can be relatively substantial for geographies with small total populations.Comment: 21 pages, 6 figure

Comment: The Essential Role of Policy Evaluation for the 2020 Census Disclosure Avoidance System

In "Differential Perspectives: Epistemic Disconnects Surrounding the US Census Bureau's Use of Differential Privacy," boyd and Sarathy argue that empirical evaluations of the Census Disclosure Avoidance System (DAS), including our published analysis, failed to recognize how the benchmark data against which the 2020 DAS was evaluated is never a ground truth of population counts. In this commentary, we explain why policy evaluation, which was the main goal of our analysis, is still meaningful without access to a perfect ground truth. We also point out that our evaluation leveraged features specific to the decennial Census and redistricting data, such as block-level population invariance under swapping and voter file racial identification, better approximating a comparison with the ground truth. Lastly, we show that accurate statistical predictions of individual race based on the Bayesian Improved Surname Geocoding, while not a violation of differential privacy, substantially increases the disclosure risk of private information the Census Bureau sought to protect. We conclude by arguing that policy makers must confront a key trade-off between data utility and privacy protection, and an epistemic disconnect alone is insufficient to explain disagreements between policy choices.Comment: Version accepted to Harvard Data Science Revie

Correlation of High-Risk Soft Tissue Sarcoma Biomarker Expression Patterns with Outcome following Neoadjuvant Chemoradiation

© 2018 John M. Kane III et al. Background. Sarcoma mortality remains high despite adjuvant chemotherapy. Biomarker predictors of treatment response and outcome could improve treatment selection. Methods. Tissue microarrays (TMAs) were created using pre- and posttreatment tumor from two prospective trials (MGH pilot and RTOG 9514) of neoadjuvant/adjuvant MAID chemotherapy and preoperative radiation. Biomarkers were measured using automated computerized imaging (AQUA or ACIS). Expression was correlated with disease-free survival (DFS), distant disease-free survival (DDFS), and overall survival (OS). Results. Specimens from 60 patients included 23 pretreatment (PRE), 40 posttreatment (POST), and 12 matched pairs (MPs). In the MP set, CAIX, GLUT1, and PARP1 expression significantly decreased following neoadjuvant therapy, but p53 nuclear/cytoplasmic (N/C) ratio increased. In the PRE set, no biomarker expression was associated with DFS, DDFS, or OS. In the POST set, increased p53 N/C ratio was associated with a significantly decreased DFS and DDFS (HR 4.13, p=0.017; HR 4.16, p=0.016), while increased ERCC1 and XPF expression were associated with an improved DFS and DDFS. No POST biomarkers were associated with OS. Conclusions. PRE biomarker expression did not predict survival outcomes. Expression pattern changes after neoadjuvant chemoradiation supports the concepts of tumor reoxygenation, altered HIF-1α signaling, and a p53 nuclear accumulation DNA damage response. Clinical Trial Registration. NRG Oncology RTOG 9514 is registered with ClinicalTrials.gov. The ClinicalTrials.gov Identifier is NCT00002791