Tribute to Paul Oberst

A tribute to Professor Paul Oberst

Tribute to Donald A. Winslow

This article is comprised of a series of tributes to Donald A. Winslow, who was a law professor at the University of Kentucky College of Law

Gauge Invariance, Finite Temperature and Parity Anomaly in D=3

The effective gauge field actions generated by charged fermions in $QED_3$ and $QCD_3$ can be made invariant under both small and large gauge transformations at any temperature by suitable regularization of the Dirac operator determinant, at the price of parity anomalies. We resolve the paradox that the perturbative expansion is not invariant, as manifested by the temperature dependence of the induced Chern-Simons term, by showing that large (unlike small) transformations and hence their Ward identities, are not perturbative order-preserving. Our results are illustrated through concrete examples of field configurations.Comment: 4 pages, RevTe

Estrogen Receptor Alpha Expression in Ovarian Cancer Predicts Longer Overall Survival

Estrogen as a potential factor of ovarian carcinogenesis, acts via two nuclear receptors, estrogen receptor alpha (ERα) and estrogen receptor beta (ERβ), but the cellular signal pathways involved are not completely clear so far. In this study we have described the expression of ERα, detected by immunocytochemistry in 11 ovarian carcinoma cell lines and by immunohistochemistry in 43 Federation Internationale des Gyneacologistes et Obstetristes stage III ovarian carcinoma specimens prepared before and after treatment with cisplatin-based schemes. For cisplatin resistance is a major obstacle in the treatment of ovarian carcinoma, analysis of cisplatin sensitivity in 11 ovarian carcinoma cell line was also performed. The strong nuclear ERα expression was only shown in the single A2780P cell line. Expression of ERα in tissue specimens did not reveal any correlations between histopathological parameters (histologic type and grading). We demonstrated a significant association with ERα expression in specimens from primary laparotomies (PL) and cause–specific survival. In the cases terminated by death of the patient, overall immunoreactivity score of ERα expression at PL was significantly lower than in surviving patients. In addition, Kaplan-Meier analysis revealed significantly shorter overall survival time and progression-free time in cases with lower immunoreactivity score of ERα expression at PL. Our findings support the hypothesis that aberrant hormone activity, by way of altered receptor expression, might be an important factor in the malignant transformation of ovarian cancer

Mimicking photosynthesis, but just the best bits

CorrespondenceInternational audienc

Tribute to Paul Oberst

A tribute to Professor Paul Oberst

Tribute to Donald A. Winslow

This article is comprised of a series of tributes to Donald A. Winslow, who was a law professor at the University of Kentucky College of Law