28 research outputs found
The role of prosthetic repair in the treatment of an incarcerated recurrent inguinal hernia with acute appendicitis (inflamed Amyand’s hernia)
Thyroid neurofibroma in a female patient with neurofibromatosis type I: report of a case
Need for restoration of cortisol serum levels for successful antimicrobial therapy in experimental sepsis
The effect of the type of intraperitoneally implanted prosthetic mesh on the systemic inflammatory response
Background: The purpose of this study was to determine any differences in the systemic inflammatory response after the intraperitoneal implantation of three different types of polypropylene mesh. Methods: Thirty-two male New Zealand rabbits underwent a 6-cm midline incision and opening of the peritoneal cavity. The animals were randomly divided into four groups. In groups A, B, and C, there was an intraperitoneal placement of polypropylene mesh, titanium-coated polypropylene mesh, and composite polypropylene/e-PTFE mesh, respectively. Group D received a sham operation. Blood was sampled preoperatively and at 6, 24, 48, and 168 h postoperatively to measure white blood cell count (WBC), tumor necrosis factor-alpha (TNF-α), and malondialdehyde (MDA). Results: Statistically significant elevations of WBC, TNF-α and MDA were observed in all four groups at 6, 24, and 48 h postoperatively (P < 0.05). There were no statistically significant differences in WBC, TNFα, and MDA between groups A, B, and C at any time interval. However, a statistically significant elevation of WBC (P < 0.05) and TNFα (P < 0.05) was observed between each of the groups with mesh implantation and group D at 24 h postoperatively. Conclusion: Intraperitoneal mesh implantation induces mild systemic inflammatory response regardless of the type of implanted mesh. © Springer-Verlag 2008