2,107 research outputs found

    Childhood Malnutrition In China: Change Of Inequality In A Decade

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    A concentration index methodology to analyze the inequality in childhood malnutrition in China is outlined. Height-for-age z score is used as a measure of childhood malnutrition. Using household survey data from nine Chinese provinces, it is found that per-capita household income, household head's education, urban residence and access to a bus stop reduced malnutrition. Child's age had a nonlinear effect on the malnutrition status. Income growth and access to public transportation reduced the inequality, while rural-urban gap, provincial differentiation, and unequal distribution of household head's education increased inequality in childhood malnutrition. Gender is not a factor in either malnutrition status or inequality. Investments in infrastructure and welfare programs are recommended to reduce the inequality.Food Consumption/Nutrition/Food Safety,

    Prediction of geomagnetic storm strength from inner heliospheric in situ observations

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    Prediction of the effects of coronal mass ejections (CMEs) on Earth strongly depends on knowledge of the interplanetary magnetic field southward component, B z . Predicting the strength and duration of B z inside a CME with sufficient accuracy is currently impossible, forming the so-called B z problem. Here, we provide a proof-of-concept of a new method for predicting the CME arrival time, speed, B z , and resulting disturbance storm time (Dst) index on Earth based only on magnetic field data, measured in situ in the inner heliosphere (<1 au). On 2012 June 12–16, three approximately Earthward-directed and interacting CMEs were observed by the Solar Terrestrial Relations Observatory imagers and Venus Express (VEX) in situ at 0.72 au, 6° away from the Sun–Earth line. The CME kinematics are calculated using the drag-based and WSA–Enlil models, constrained by the arrival time at VEX, resulting in the CME arrival time and speed on Earth. The CME magnetic field strength is scaled with a power law from VEX to Wind. Our investigation shows promising results for the Dst forecast (predicted: −96 and −114 nT (from 2 Dst models); observed: −71 nT), for the arrival speed (predicted: 531 ± 23 km s−1; observed: 488 ± 30 km s−1), and for the timing (6 ± 1 hr after the actual arrival time). The prediction lead time is 21 hr. The method may be applied to vector magnetic field data from a spacecraft at an artificial Lagrange point between the Sun and Earth or to data taken by any spacecraft temporarily crossing the Sun–Earth line

    FRESH VEGETABLE PRICE LINKAGE BETWEEN GROWER/SHIPPERS, WHOLESALERS AND RETAILERS

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    This study focused on the transmission of price adjustments between grower/shippers and wholesalers and between wholesale handlers and retailers of nine fresh vegetables (only the results associated with bell peppers are reported in this paper). Results among the nine vegetable products were not consistent with respect to the magnitude of adjustments or the time periods involved in the adjustments. In response to wholesale price changes, upward price adjustments at the retail level occur more quickly than do downward price adjustments. Price transmission relationships also varied among the vegetable products between the wholesaler and grower. Overall, the results indicate that factors in addition to changes in upstream prices are impacting retailers' and wholesalers' pricing decisions.Demand and Price Analysis,

    Super-Alfv\'enic propagation of reconnection signatures and Poynting flux during substorms

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    The propagation of reconnection signatures and their associated energy are examined using kinetic particle-in-cell simulations and Cluster satellite observations. It is found that the quadrupolar out-of-plane magnetic field near the separatrices is associated with a kinetic Alfv\'en wave. For magnetotail parameters, the parallel propagation of this wave is super-Alfv\'enic (V_parallel ~ 1500 - 5500 km/s) and generates substantial Poynting flux (S ~ 10^-5 - 10^-4 W/m^2) consistent with Cluster observations of magnetic reconnection. This Poynting flux substantially exceeds that due to frozen-in ion bulk outflows and is sufficient to generate white light aurora in the Earth's ionosphere.Comment: Submitted to PRL on 11/1/2010. Resubmitted on 4/5/201

    Ethnic Differences in Associations Between Blood Pressure and Stroke in South Asian and European Men.

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    It is unknown whether associations between blood pressure (BP) and stroke vary between Europeans and South Asians, despite higher stroke rates in the latter. We report findings from a UK cohort study of 1375 European and 1074 South Asian men, not receiving antihypertensive medication, aged 40 to 69 years at baseline (1988-1991). Assessment included BP, blood tests, anthropometry, and questionnaires. Incident stroke was established at 20 years from death certification, hospital and primary care records, and participant report. South Asians had higher systolic BP, diastolic BP, and mean arterial pressure than Europeans, and similar pulse pressure. Associations between systolic BP or diastolic BP and stroke were stronger in South Asians than Europeans, after adjustment for age, smoking status, waist/hip ratio, total/high-density lipoprotein-cholesterol ratio, diabetes mellitus, fasting glucose, physical activity, and heart rate (systolic BP: Europeans [odds ratio, 1.22; 95% confidence interval, 0.98-1.51], South Asians [1.56; 1.24-1.95]; ethnic difference P=0.04; diastolic BP: Europeans [0.90; 0.71-1.13], South Asians [1.68; 1.32-2.15]; P<0.001). Hemodynamic correlates of stroke risk differed by ethnicity: in combined models, mean arterial pressure but not pulse pressure was detrimentally associated with stroke in South Asians, whereas the converse was true for Europeans. The combination of hyperglycemia and hypertension appeared particularly detrimental for South Asians. There are marked ethnic differences in associations between BP parameters and stroke. Undue focus on systolic BP for risk prediction, and current age and treatment thresholds may be inappropriate for individuals of South Asian ancestry

    Thigh fat and muscle each contribute to excess cardiometabolic risk in South Asians, independent of visceral adipose tissue.

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    OBJECTIVE: To compare fat distribution and associations between fat depots and cardiometabolic traits in South Asians and Europeans. METHODS: Five hundred and fourteen South Asians and 669 Europeans, aged 56-86. Questionnaires, record review, blood testing, and coronary artery calcification scores provided diabetes and clinical plus subclinical coronary heart disease (CHD) diagnoses. Abdominal visceral (VAT) and subcutaneous adipose tissue, thigh subcutaneous adipose tissue (TSAT), intermuscular and intramuscular thigh fat and thigh muscle were measured by CT. RESULTS: Accounting for body size, South Asians had greater VAT and TSAT than Europeans, but less thigh muscle. Associations between depots and disease were stronger in South Asians than Europeans. In multivariable analyses in South Asians, VAT was positively associated with diabetes and CHD, while TSAT and thigh muscle were protective for diabetes, and thigh muscle for CHD. Differences in VAT and thigh muscle only partially explained the excess diabetes and CHD in South Asians versus Europeans. Insulin resistance did not account for the effects of TSAT or thigh muscle. CONCLUSIONS: Greater VAT and TSAT and lesser thigh muscle in South Asians contributed to ethnic differences in cardiometabolic disease. Effects of TSAT and thigh muscle were independent of insulin resistance

    KLF6 and STAT3 Co-Occupy Regulatory DNA and Functionally Synergize to Promote Axon Growth in CNS Neurons

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    The failure of axon regeneration in the CNS limits recovery from damage and disease. Members of the KLF family of transcription factors can exert both positive and negative effects on axon regeneration, but the underlying mechanisms are unclear. Here we show that forced expression of KLF6 promotes axon regeneration by corticospinal tract neurons in the injured spinal cord. RNA sequencing identified 454 genes whose expression changed upon forced KLF6 expression in vitro, including sub-networks that were highly enriched for functions relevant to axon extension including cytoskeleton remodeling, lipid synthesis, and bioenergetics. In addition, promoter analysis predicted a functional interaction between KLF6 and a second transcription factor, STAT3, and genome-wide footprinting using ATAC-Seq data confirmed frequent co-occupancy. Co-expression of the two factors yielded a synergistic elevation of neurite growth in vitro. These data clarify the transcriptional control of axon growth and point the way toward novel interventions to promote CNS regeneration

    The effects of weight and physical activity change over 20 years on later-life objective and self-reported disability.

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    Weight and health behaviours are known to affect physical disability; however the evidence exploring the impact of changes to these lifestyle factors over the life course on disability is inconsistent. We aimed to explore the roles of weight and activity change between mid and later life on physical disability
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