Brain Activation During Passive and Volitional Pedaling After Stroke

Background: Prior work indicates that pedaling-related brain activation is lower in people with stroke than in controls. We asked whether this observation could be explained by between-group differences in volitional motor commands and pedaling performance. Methods: Individuals with and without stroke performed passive and volitional pedaling while brain activation was recorded with functional magnetic resonance imaging. The passive condition eliminated motor commands to pedal and minimized between-group differences in pedaling performance. Volume, intensity, and laterality of brain activation were compared across conditions and groups. Results: There were no significant effects of condition and no Group × Condition interactions for any measure of brain activation. Only 53% of subjects could minimize muscle activity for passive pedaling. Conclusions: Altered motor commands and pedaling performance are unlikely to account for reduced pedaling-related brain activation poststroke. Instead, this phenomenon may be due to functional or structural brain changes. Passive pedaling can be difficult to achieve and may require inhibition of excitatory descending drive

Evaluation of the effects of a freeze/thaw environment on cellular glass

Using the evaluation criteria of water vapor permeability and conformability, a protective butylrubber/silicone conformal coating system was selected for use on Foamglas substrates in a freeze/thaw environment. The selection of a specific freeze/thaw cycle which closely models field conditions is discussed. A sampling plan is described which allows independent evaluation of the effects of conformal coatings, cycle number and location within the environmental chamber. The results of visual examination, measurement of density, modulus of rupture and Young's modulus are reported. Based upon statistical evaluation of the experimental results, it is concluded that no degradation in mechanical properties of either coated or uncoated Foamglas occurred within the duration of the test (53 freeze/thaw cycles)

The ATLAS liquid argon hadronic end-cap calorimeter: construction and selected beam test results

ATLAS has chosen for its Hadronic End-Cap Calorimeter (HEC) the copper-liquid argon sampling technique with flat plate geometry and GaAs pre-amplifiers in the argon. The contruction of the calorimeter is now approaching completion. Results of production quality checks are reported and their anticipated impact on calorimeter performance discussed. Selected results, such as linearity, electron and pion energy resolution, uniformity of energy response, obtained in beam tests both of the Hadronic End-Cap Calorimeter by itself, and in the ATLAS configuration where the HEC is in combination with the Electromagnetic End-Cap Calorimeter (EMEC) are described.Comment: 4 pages, 2 figures,IPRD04 conferenc

Generation and detection of NOON states in superconducting circuits

NOON states, states between two modes of light of the form $|N,0\rangle+e^{i\phi}|0,N\rangle$ allow for super-resolution interformetry. We show how NOON states can be efficiently produced in circuit quntum electrodynamics using superconducting phase qubits and resonators. We propose a protocol where only one interaction between the two modes is required, creating all the necessary entanglement at the start of the procedure. This protocol makes active use of the first three states of the phase qubits. Additionally, we show how to efficiently verify the success of such an experiment, even for large NOON states, using randomly sampled measurements and semidefinite programming techniques.Comment: 15 pages and 3 figure

Reliability and Validity of Ratings of Perceived Exertion in Persons With Multiple Sclerosis

Objective: To test the reliability and validity of using the Borg rating of perceived exertion (RPE) scale (ratings 6e20) in persons with multiple sclerosis (PwMS). Design: Nonrandomized repeated measures. Setting: Research laboratory. Participants: Volunteer sample (N=27) comprised of 16 PwMS (10 women) and 11 age-matched persons without multiple sclerosis (MS) (6 women). Clinical measures included symptomatic fatigue, depression, and MS functional capacity. Interventions: A submaximal cycling test was performed to estimate maximal capacity. Participants then pedaled for 2 minutes at 50% and 60% of predicted maximal oxygen consumption per unit time (V̇O2), and physiological measures and RPE were obtained (week 1: response protocol). One week later, participants replicated the prescribed V̇O2 using the RPE range from week 1 (week 2: reproduction protocol). V̇O2, heart rate, and respiratory quotient were measured continuously; RPE and workload were measured every minute; and blood lactate and mean arterial pressure were measured after exercise. Main Outcome Measures: RPE, workload, V̇O2, and heart rate from week 1 to week 2. Results: PwMS had greater fatigue (P2, and heart rate were similar between groups. Both groups had an intraclass correlation coefficient \u3e.86 for RPE, workload, and V̇O2. The intraclass correlation coefficient was comparatively lower for heart rate for both groups (MS group: .72, non-MS group: .83). RPE was highly correlated with V̇O2(rZ.691, P Conclusions: Results suggest that RPE can be reliably reproduced, is valid, and may be used in exercise prescription in mildly to moderately impaired PwMS during cycling exercise

The year in cardiology: heart failure. The year in cardiology 2019.

No abstract available

Development of a technology adoption and usage prediction tool for assistive technology for people with dementia

This article is available open access through the publisher’s website at the link below. Copyright @ The Authors 2013.In the current work, data gleaned from an assistive technology (reminding technology), which has been evaluated with people with Dementia over a period of several years was retrospectively studied to extract the factors that contributed to successful adoption. The aim was to develop a prediction model with the capability of prospectively assessing whether the assistive technology would be suitable for persons with Dementia (and their carer), based on user characteristics, needs and perceptions. Such a prediction tool has the ability to empower a formal carer to assess, through a very limited amount of questions, whether the technology will be adopted and used.EPSR

Dynamics of a suspended nanowire driven by an ac Josephson current in an inhomogeneous magnetic field

We consider a voltage-biased nanoelectromechanical Josephson junction, where a suspended nanowire forms a superconducting weak-link, in an inhomogeneous magnetic field. We show that a nonlinear coupling between the Josephson current and the magnetic field generates a Laplace force that induces a whirling motion of the nanowire. By performing an analytical and a numerical analysis, we demonstrate that at resonance, the amplitude-phase dynamics of the whirling movement present different regimes depending on the degree of inhomogeneity of the magnetic field: time independent, periodic and chaotic. Transitions between these regimes are also discussed.Comment: 7 pages, 5 figure