Особенности артропатии при болезни Уиппла

The authors describe a case of Whipple's disease (WD) in a 56-year-old male patient followed up for 2 years. The diagnosis was established on the evidence that there was a low-density retroperitoneal or mesenteric infiltrate at computed tomography and PAS-positive macrophages in the biopsy specimens of the duodenal retrobulbar mucosa. Arthropathy had developed within 10 years before the occurrence of intestinal symptoms, subsided with their progression, and recurred after their regression. On the basis of this observation and the data available in the literature, the authors discuss the relationships of arthropathy to the abdominal manifestations of WD.Описано двухлетнее клиническое наблюдение мужчины 56 лет с болезнью Уиппла (БУ). Диагноз был установлен на основании обнаружения при компьютерной томографии расположенного за брюшиной и в брыжейке тонкой кишки инфильтрата низкой рентгеновской плотности и выявления в биоптате слизистой оболочки залуковичного отдела двенадцатиперстной кишки PAS-позитив-ных макрофагов. Артропатия развилась за 10 лет до появления кишечной симптоматики, стихла с ее развитием и возобновилась после достижения клинической ремиссии. На основании данного наблюдения и данных литературы обсуждаются взаимоотношения артропатии и абдоминальных проявлений БУ

The specific features of arthropathy in Whipple's disease

The authors describe a case of Whipple's disease (WD) in a 56-year-old male patient followed up for 2 years. The diagnosis was established on the evidence that there was a low-density retroperitoneal or mesenteric infiltrate at computed tomography and PAS-positive macrophages in the biopsy specimens of the duodenal retrobulbar mucosa. Arthropathy had developed within 10 years before the occurrence of intestinal symptoms, subsided with their progression, and recurred after their regression. On the basis of this observation and the data available in the literature, the authors discuss the relationships of arthropathy to the abdominal manifestations of WD

Treatment of peptic ulcer bleeding and prevention of recurrence: a therapist's perspective

Gastroduodenal bleeding may complicate a variety of diseases of the esophagus, stomach, duodenum and hepatopancreatobiliary system. Patient's life ultimatley depends on how well a clinician is informed in modern diagnosis methods and how capable he/she is of making an adequate treatment choice [1]