4 research outputs found
Teratological Study of the Antioxidant Stobadine in Rats
Abstract. The potential teratogenicity of the antioxidant stobadine (STO) was studied in Wistar rats. Daily oral doses of 5, 15 and 50 mg/kg STO were given from the 6th day of gestation up to weaning of pups -day 21 post partum. No significant differences between the STO treated groups and the control group were found in litter size, pre-and postimplantation losses and foetal body weight. Ex ternal, skeletal and internal examinations of the foetuses revealed no evidence of teratogenesis. The offspring from the STO treated dams exhibited a high survival rate in their postnatal development. It can be concluded that STO had no adverse effects on the pre-and postnatal development of the offspring in rats
Determining absolute electrochemiluminescence efficiencies of two iridium complexes
This work reports absolute electrochemiluminescence (ECL) quantum efficiencies (QEs) of two iridium(III) complexes, fac-Ir(ppy)3 (Ir-1) and [Ir(ppy)2(dtbubpy)]+ ([Ir-2]+) in annihilation and coreactant pathways. With potentiodynamic scans and potential pulsing, ECL mechanisms were investigated by means of ECL-voltage curves, ECL-time curves and ECL spectroscopy. It was demonstrated that the radical stability and reactivity are the two main factors affecting ECL efficiencies in various processes, while intermediate charges have little effect. Considering the difference of such radical behaviors between [Ru(bpy)3]2+ and other luminophores, absolute ECL QEs are more applicable compared with the ones relative to [Ru(bpy)3]2+ as a standard
Determining absolute electrochemiluminescence efficiencies of two iridium complexes
This work is financially supported by Natural Sciences and Engineering Research Council Canada (NSERC, DG RGPIN-2018-06556 and SPG STPGP-2016-493924), Canada Foundation of Innovation/Ontario Innovation Trust (CFI/OIT, 9040) and The University of Western Ontario. E. Z.-C. is a Royal Society Leverhulme Trust Senior Research fellow (SRF\R1\201089).This work reports absolute electrochemiluminescence (ECL) quantum efficiencies (QEs) of two iridium(III) complexes, fac-Ir(ppy)3 (Ir-1) and [Ir(ppy)2(dtbubpy)]+ ([Ir-2]+) in annihilation and coreactant pathways. With potentiodynamic scans and potential pulsing, ECL mechanisms were investigated by means of ECL-voltage curves, ECL-time curves and ECL spectroscopy. It was demonstrated that the radical stability and reactivity are the two main factors affecting ECL efficiencies in various processes, while intermediate charges have little effect. Considering the difference of such radical behaviors between [Ru(bpy)3]2+ and other luminophores, absolute ECL QEs are more applicable compared with the ones relative to [Ru(bpy)3]2+ as a standard.PostprintPeer reviewe