NİMETA’NIN AŞK TÜRKÜSÜ

Ayşe Kulin’in Sevdalinka adlı yapıtında “aşk” ve “savaş” kavramları hangi yönleriyle ele alınmıştır

Multiple sclerosis prevalence study the comparison of 3 coastal cities, located in the black sea and mediterranean regions of Turkey

The prevalence of multiple sclerosis (MS) has significantly increased all over the world. Recent studies have shown that Turkey has quite a high prevalence. The aim of this study is to estimate prevalence in the Mediterranean and Black Sea regions of Turkey and to compare the results. This study was designed as a door to door survey in 3 cities. One is located in the Mediterranean region (South), 2 are located in the Black Sea region (North). A previous validated form was used for screening in the field. The patients were examined first in the field, then in the regional health facility. McDonald criteria were used for the diagnosis. In total, 26 patients were diagnosed with MS. The prevalence was found to be 18.6/100,000 in Artvin (Black Sea region), 55.5/100,000 in Ordu, (Black Sea region), 52.00/100,000 in Gazipasa (Mediterranean region). The female/male ratio was 2.25. This study is the first prevalence study which was conducted in the Mediterranean City (South) of Turkey. The prevalence rate was found to be higher than expected in the Mediterranean city of Gazipasa. The results showed that the prevalence varies from region to region. Latitude difference was not observed

Corpus callosum in schizophrenia with deficit and non-deficit syndrome: a statistical shape analysis

Background The corpus callosum (CC) is the most targeted region in the cerebrum that integrates cognitive data between homologous areas in the right and left hemispheres. Aims Our study used statistical analysis to determine whether there was a correlation between shape changes in the CC in patients with schizophrenia (SZ) (deficit syndrome (DS) and non-deficit syndrome (NDS)) and healthy control (HC) subjects. Methods This study consisted of 27 HC subjects and 50 schizophrenic patients (20 with DS and 30 with NDS). 3 patients with DS and 4 patients with NDS were excluded. Three-dimensional, sagittal, T1-spoiled, gradient-echo imaging was used. Standard anatomical landmarks were selected and marked on each image using specific software. Results As to comparing the Procrustes mean shapes of the CC, statistically significant differences were observed between HC and SZ (DS+NDS) (p=0.017, James's F-j=73.732), HC and DS (p<0.001, James's F-j=140.843), HC and NDS (p=0.006, James's F-j=89.178) and also DS and NDS (p<0.001, James's F-j=152.967). Shape variability in the form of CC was 0.131, 0.085, 0.082 and 0.086 in the HC, SZ (DS+NDS), DS and NDS groups, respectively. Conclusions This study reveals callosal shape variations in patients with SZ and their DS and NDS subgroups that take into account the CC's topographic distribution

NİMETA’NIN AŞK TÜRKÜSÜ

Ayşe Kulin’in Sevdalinka adlı yapıtında “aşk” ve “savaş” kavramları hangi yönleriyle ele alınmıştır

MULTİPL SKLEROZDA BARSAK HAREKET BOZUKLUKLARI VE AMİLOİDOZ İLE İLİŞKİSİ

Amaç: Bağırsak hareket bozuklukları, multipl sklerozlu MS hastalarda sık görülmektedir. Bu çalışmanın amacı, kolon geçiş zamanını araştırmak ve bununla birlikte bağırsak motilite bozukluklarının sıklığı, lezyonların yeri ile ilişkisi ve yineleyici multipl skleroz RR-MS hastalarında tekrarlayan amiloidoz varlığı ile ilişkisini irdelemektir. Yöntem: Bu çalışmaya klinik kesin yineleyici MS RR-MS ’i bulunan 18 hasta dahil edildi. Bağırsak motilite bozuklukları ROMAII kriterlerine göre sınıflandırıldı ve tüm hastalara kolonoskopi yapıldı. Kolonoskopik biyopsi örnekleri amiloidoz varlığı açısından değerlendirildi. Colontransit 20 pelet ile kolon geçiş süreleri hesaplandı. Bulgular: Hastaların yaş ortalaması 34,3 yıl idi. Hastaların 12’si kadın ve 6’sı erkekti. Ortalama MS süresi 7,6 yıl ve genişletilmiş özürlülük durumu skoru EDSS ortalama 2,0 olarak bulundu. Hastaların 12’sinde kabızlık ve 3’ünde ishal bulundu. Hastalarda bağırsak motilite bozuklukları kabızlık ve ishal nükslerden 2±1 gün önce ortaya çıkmakta ve nüksler sırasında da devam etmekte idi. İstatistiksel olarak, bağırsak işlev bozukluğu ile atak sayısı arasında p = 0,021 korelasyon saptandı. Kolon geçiş süresi ile atak sayısı ve MS süresi sırasıyla p = 0,013, p = 0,006 arasında istatistiksel olarak anlamlı bir ilişki vardı ve buna ek olarak hiçbir hastanın biyopsisinde amiloidoz saptanmadı. Sonuç: Bu çalışmada, uzun süreli kolon geçiş zamanı ve yineleyici MS hastalarında bağırsak işlev bozukluğu özellikle kabızlık varlığını göstermektedir. Patofizyolojisi ise henüz tam bilinmemektedi

Stroke epidemiology in Karabük city Turkey: Community based study

Introduction: Stroke has been projected to increase in developing countries like Turkey. Information about the prevalence of stroke may uncover the etiology of stroke and overcome its impact burden. However, data is limited due to a lack of studies based in Turkey and neighboring regions. We aimed to investigate the prevalence and risk factors of stroke in the Turkish city of Karabük and to pave the way for future epidemiological studies in Turkey. Methods: The study was designed as a cross-sectional, door-to-door survey. The questionnaire was completed by a trained team in the presence of the participants according to their answers. Patients who had been diagnosed with stroke prior to the survey were re-examined by a neurologist. Results: 3131 persons who were above 44years old were screened. 129 of them were found to have had a stroke previously. The prevalence rate of stroke above 44years was found to be 4.12% (98% confidence level and ±2% margin of error). 72.1% of stroke patients had hypertension. Male/female ratio was 0.72. Conclusion: This study showed a high prevalence rate of stroke in Karabük Turkey with a low male/female ratio when compared to other studies. Keywords: Stroke, Epidemiology, Turkey, Risk factor

Stroke prevalence among the Turkish population in a rural area of Istanbul: A community-based study

Background: The population-based information on the prevalence of stroke from rural areas of Middle East countries including Turkey is unknown. Our aim is to evaluate the prevalence of stroke in those ⩾18 years in the Turkish population in a rural area of Istanbul. Methods: A cross-sectional door-to-door study was conducted in a rural area of Istanbul between 1 March and 30 March 2013. A research protocol recommended by World Health Organization for developing countries was used. Each screening teams consisted of one neurologist, one local nurse, and five surveyors. Teams were trained about the survey and questionnaire. The patients, who claimed to have suffered a stroke, were examined, and the diagnosis was confirmed by a neurologist on site. The findings and medical records were documented. Results: In total, 2906 people ⩾18 years were screened. 50 stroke cases were detected. 80% of those were found to have had an ischemic stroke, 14% of those were hemorrhagic cases, and 6% of those had an unclassified stroke type. The overall prevalence rate in those ⩾ 18 years was 1.7%. The male/female ratio was 0.92. Young (<45) stroke prevalence was found to be 0.6%. Conclusion: This study was the first of its kind to show the stroke prevalence among Turkish population ⩾ 18 years in a rural area of Istanbul. When compared to other studies which investigate people ⩾45 years from Turkey, the result (in the same age group) was moderate high. The male/female ratio was low compared to many other studies