14 research outputs found
PAR-2 AND PAR-4 RECEPTORS MEDIATE ANTI-INFLAMMATORY EFFECTS OF ACTIVATED PROTEIN C IN MICROGLIAL CELLS
No full textInvestigation of the effect of melatonin on microRNA expression in the NLRP3 inflammasome model
No full textEndothelial Protein C Receptor Expression is Regulated by Sp1 Transcription Factor in Murine Microglia
No full textObjectives: Microglial cells are the central regulators of inflammatory responses in the brain and spinal cord. In addition to surveillance during resting state, they become activated due to microbial molecules and pathological insults. Endogenously expressed Activated protein C (APC) is an anticoagulant molecule with anti-inflammatory and cytoprotective roles, mediated by one of its receptors, Endothelial protein C receptor (EPCR). This study aimed to examine the basal and inducible expression of EPCR and unravel the regulatory mediators of its expression in microglia
Therapeutic Proteins and Peptides (Advances in protein chemistry and structural biology, Volume 112)
No full textMicroglial phenotypes are determined by variable intracellular hydrogen peroxide concentrations
No full textSulforaphane produces anti inflammatory effects by inhibiting NLRR3 inflammasome activation in microglial cells
No full textHiperoksi Beyin Enerjisi Metabolizmasında Glikoliz Yolağından Pentoz Fosfat Yolağına Yönelmeye Neden Olabilir Mi?
No full text
Hiperoksi beyin enerjisi metabolizmasında glikoliz yolağından pentoz fosfat yolağına yönelmeye neden olabilir mi?/Does hyperoxia cause a shift in brain energy metabolism from glycolysis to pentose phosphate pathway?
No full text
