Obesity - an epidemic of the 21st century – literature review

Introduction and purpose: The article deals with the problem of obesity, which significantly increases the number of cases among children, adolescents and adults all over the world, leading to the occurrence of systemic disorders. A noticeable increase in the incidence of atherosclerosis, metabolic syndrome and diabetes leads to a reduction in life expectancy. The main aim of the work is to emphasize the seriousness of the contemporary problem, which causes impairment of the functioning of many systems. A secondary goal is to indicate the current standards of obesity treatment and how to deal with overweight.   Brief description of the state of knowledge: Obesity is a disease that affects nearly 800 million people around the world and affects every fourth Pole. Uncontrolled weight gain is caused; lifestyle changes, consumption of highly processed foods, and genetic and endocrine factors. It is a chronic disease with a tendency to relapse, with serious consequences and in need of diagnostics, personalized treatment, and often associated with psychological support.   Material and methods: The article analyzes the research to date and the latest treatment methods, which show that a person struggling with obesity is at risk of over 200 complications, including, for example, fatty liver, stroke, type 2 diabetes or cancer.   Results and conclusion:  According to our analysis, obesity is a pathological condition that is truly life-threatening. Despite the society's downplay of the problem, people affected by this disease struggle with many comorbidities that worsen their quality of life

Obesity - an epidemic of the 21st century – literature review

Introduction and purpose: The article deals with the problem of obesity, which significantly increases the number of cases among children, adolescents and adults all over the world, leading to the occurrence of systemic disorders. A noticeable increase in the incidence of atherosclerosis, metabolic syndrome and diabetes leads to a reduction in life expectancy. The main aim of the work is to emphasize the seriousness of the contemporary problem, which causes impairment of the functioning of many systems. A secondary goal is to indicate the current standards of obesity treatment and how to deal with overweight.   Brief description of the state of knowledge: Obesity is a disease that affects nearly 800 million people around the world and affects every fourth Pole. Uncontrolled weight gain is caused; lifestyle changes, consumption of highly processed foods, and genetic and endocrine factors. It is a chronic disease with a tendency to relapse, with serious consequences and in need of diagnostics, personalized treatment, and often associated with psychological support.   Material and methods: The article analyzes the research to date and the latest treatment methods, which show that a person struggling with obesity is at risk of over 200 complications, including, for example, fatty liver, stroke, type 2 diabetes or cancer.   Results and conclusion:  According to our analysis, obesity is a pathological condition that is truly life-threatening. Despite the society's downplay of the problem, people affected by this disease struggle with many comorbidities that worsen their quality of life

The Beneficial Effects of Aerobic Exercise on Human Systems and Organs: A Literature Review

Introduction: Engaging in regular aerobic exercise can have a tremendous impact on one's physical and mental well-being. Despite the known benefits, a significant number of adults worldwide continue to lead sedentary lifestyles. Aerobic exercise, in particular, has been shown to improve lipid profiles, reducing the risk of cardiovascular diseases and mortality rates. Additionally, it promotes healthy metabolism, hormonal balance, and mental well-being, all of which contribute to overall health and quality of life. This is especially crucial for cancer patients undergoing treatment. Aim of the Study: The primary objective of this study is to conduct a comprehensive analysis of the physiological and psychological benefits of aerobic exercise on the human body. Description of the State of Knowledge: Moderate and regular aerobic exercise has been shown to have a beneficial effect on both physical and mental health. The importance of improving physical performance, overall body fitness, endurance, strength, balance, and mobility cannot be overstated, as it has a proven therapeutic and preventive effect against various diseases. Materials and methods: An unsystematic scientific literature review was conducted using specific keywords such as earobic exercise, lipid profile, cardiovascular system, cardiovascular disease, diabetes. The review was carried out on PubMed, analyzing a total of 70 sources published until 2023. Conclusions: Exercise has beneficial effects on all organ systems and is a non-pharmacological form of treatment for cardiovascular, musculoskeletal, metabolic and nervous system diseases. They have the benefits of reducing stress, lowering blood pressure, stimulating osteogenesis, and having a beneficial effect on body shape and self-perception. Exercise can be considered an effective treatment for established diseases or the alleviation of their symptoms

The Increasing Occurrence of Infectious Diseases in Childhood: Is It Linked with Declining Vaccination Rates Across Society?

Introduction. Childhood infectious diseases have been a significant medical problem, with a global increase in recent years. Modern diagnostic methods and new vaccinations are available. Poland is part of the WHO-coordinated global measles and rubella elimination program. Controversy surrounds mandatory and recommended vaccinations in Poland. There has been a concerning increase in the abandonment of vaccinating children, leading to a resurgence of infectious diseases. In 2024, the WHO reported a significant increase in measles cases in the European region, including in Poland. It's crucial to remind people of these diseases and warn them about the complications they bring. Aim of study. The aim of this study is to investigate the increasing occurrence of infectious diseases in childhood and examine the correlation with declining vaccination rates across society. Materials and methods. An unsystematic review of scientific literature was conducted, employing specific keywords such as „measles,” „pertussis,” „rubella,” „infectious diseases,” „vaccination,” and „hib.” The review was executed on the PubMed database, analyzing a total of 59 sources published until the conclusion of 2024. Conclusions. To control and eliminate infectious diseases, it is vital to maintain and improve vaccination rates. Policymakers and healthcare providers should prioritize immunization programs and address barriers to vaccine access. Further research is crucial to develop comprehensive strategies for increasing vaccination coverage and understanding vaccine-preventable diseases in modern public health challenges

The Increasing Occurrence of Infectious Diseases in Childhood: Is It Linked with Declining Vaccination Rates Across Society?

Introduction. Childhood infectious diseases have been a significant medical problem, with a global increase in recent years. Modern diagnostic methods and new vaccinations are available. Poland is part of the WHO-coordinated global measles and rubella elimination program. Controversy surrounds mandatory and recommended vaccinations in Poland. There has been a concerning increase in the abandonment of vaccinating children, leading to a resurgence of infectious diseases. In 2024, the WHO reported a significant increase in measles cases in the European region, including in Poland. It's crucial to remind people of these diseases and warn them about the complications they bring. Aim of study. The aim of this study is to investigate the increasing occurrence of infectious diseases in childhood and examine the correlation with declining vaccination rates across society. Materials and methods. An unsystematic review of scientific literature was conducted, employing specific keywords such as „measles,” „pertussis,” „rubella,” „infectious diseases,” „vaccination,” and „hib.” The review was executed on the PubMed database, analyzing a total of 59 sources published until the conclusion of 2024. Conclusions. To control and eliminate infectious diseases, it is vital to maintain and improve vaccination rates. Policymakers and healthcare providers should prioritize immunization programs and address barriers to vaccine access. Further research is crucial to develop comprehensive strategies for increasing vaccination coverage and understanding vaccine-preventable diseases in modern public health challenges

Ozempic (semaglutide) - review of pharmacological properties, mechanism of action and clinical applications

Introduction: Ozempic is a new generation antihyperglycemic drug used to treat type 2 diabetes in adults whose underlying disease is not sufficiently controlled with physical activity and diet, as well as for long-term weight control in people with excess body weight and comorbidities. The aim of this study is to explore and integrate the latest literature on the analysis of the pharmacology, mechanism of action and clinical applications of Ozempic. Material and Methods of Research: A literature review focused on keywords related to the topic was performed using databases such as PubMed and Google Scholar. Results: Ozempic effectively lowers blood glucose levels and supports weight loss in patients with type 2 diabetes and obesity. Clinical trials have demonstrated its superiority over other antidiabetic medications, with significant reductions in HbA1c and body weight. Patients receiving Ozempic experienced improved glycemic control and cardiovascular outcomes, with manageable side effects. Ongoing research suggests additional benefits in cardiovascular prevention and obesity management. Conclusion: Ozempic (semaglutide) is a potent GLP-1 receptor agonist that effectively improves glycemic control and aids in weight reduction for patients with type 2 diabetes and obesity. Its practical administration, patient education, and regular monitoring are essential for optimal outcomes. Ongoing research and technological advancements, including the development of oral forms, promise to expand its applications and improve patient adherence, making Ozempic a versatile and valuable therapeutic option