TRANSFERENCIA EMBRIONARIA IPSILATERAL Y CONTRALATERAL A LA POSICIÓN DEL CUERPO LÚTEO Y SUPERVIVENCIA EMBRIONARIA EN LLAMAS.

The study was carried out to evaluate the effect the embryo transfer to the uterinehorn ipsilateral and contralateral to the side of the corpus luteum (CL) and the size of CLon the embryo survival in llamas. It was used 43 recipient adult females randomly assignedto 4 groups: G1 (n=10): CL in right ovary and ipsilateral embryo transfer, G2 (n=10): CL inright ovary and contralateral transfer, G3 (n=15): CL in left ovary and ipsilateral transfer,and G4 (n=8): CL in left ovary and contralateral transfer. Ten llamas were used as embryodonors. They were synchronized with LH (1 ml) on Day 0 (D0), superovulated with 1000UI eCG on D3, luteolysis was induced with PGF2?on D7, and mated on D8. Recipientswere treated on D7 with LH to get synchrony with the donors. On D14 embryos werecollected, evaluated and transferred. The results showed that 60 (G1) and 75% (G3)recipients conceived when embryo transfer was right and left ipsilateral respectively,while only 30 (G2) and 25% (G4) conceived when embryo transfer was right and leftcontralateral respectively. However, statistical difference was only observed between G3with G2 and G4 (p<0.05). These results indicate that pregnancy rate is higher in llamaswhen the embryo transfer was done in to the uterine horn ipsilateral to the CL in the leftovary.El presente trabajo se realizó con el propósito de evaluar el efecto de la transferencia embrionaria ipsilateral y contralateral a la posición del cuerpo lúteo (CL), así como el tamaño del CL sobre la tasa de supervivencia embrionaria en llamas. Se utilizaron 43 llamas receptoras, adultas, distribuidas aleatoriamente en 4 grupos: G1 (n=10): CL en ovario derecho y transferencia ipsilateral, G2 (n=10): CL en ovario derecho y transferencia contralateral, G3 (n=15): CL en ovario izquierdo y transferencia ipsilateral y G4 (n=8): CL en ovario izquierdo y transferencia contralateral. Se usaron 10 llamas como donadoras de embriones, que fueron sincronizadas con LH (1 ml) (Día 0=D0), superovuladas con 1000 UI de eCG en el D3, a las que se les provocó luteólisis con PGF2αen el D7 y se les empadró en el D8. Ese día, las receptoras se trataron con LH para sincronizarlas con las donadoras. En el D14 se colectó, evaluó y transfirió los embriones. El 60 (G1) y 75% (G3) de las hembras preñaron con transferencia ipsilateral derecha e izquierda, respectivamente, mientras solo el 30 (G2) y 25% (G4) preñaron con transferencia contralateral derecha e izquierda, respectivamente. Sin embargo, solo se encontró diferencia significativa entre el grupo G3 con los grupos G2 y G4 (p<0.05). Los resultados indican una mayor tasa de supervivencia embrionaria en llamas al realizar la transferencia en el cuerno ipsilateral a la posición del CL ubicado en el ovario izquierdo

Prevalence of Low Cardiovascular Risk Profile Among Diverse Hispanic/Latino Adults in the United States by Age, Sex, and Level of Acculturation: The Hispanic Community Health Study/Study of Latinos

BACKGROUND: Favorable levels of all readily measurable major cardiovascular disease risk factors (ie, low risk [LR]) are associated with lower risks of cardiovascular disease morbidity and mortality. Data are not available on LR prevalence among Hispanic/Latino adults of diverse ethnic backgrounds. This study aimed to describe the prevalence of a low cardiovascular disease risk profile among Hispanic/Latino adults in the United States and to examine cross-sectional associations of LR with measures of acculturation. METHODS AND RESULTS: The multicenter, prospective, population-based Hispanic Community Health Study/Study of Latinos examined 16 415 men and women aged 18 to 74 years at baseline (2008-2011) with diverse Hispanic/Latino backgrounds. Analyses involved 14 757 adults (mean age 41.3 years; 60.6% women). LR was defined using national guidelines for favorable levels of serum cholesterol, blood pressure, and body mass index and by not having diabetes mellitus and not currently smoking. Age-adjusted LR prevalence was low (8.4% overall; 5.1% for men, 11.2% for women) and varied by background (4.2% in men of Mexican heritage versus 15.0% in women of Cuban heritage). Lower acculturation (assessed using proxy measures) was significantly associated with higher odds of a LR profile among women only: Age-adjusted odds ratios of having LR were 1.64 (95% CI 1.24-2.17) for foreign-born versus US-born women and 1.96 (95% CI 1.49-2.58) for women residing in the United States <10 versus ≥10 years. CONCLUSIONS: Among diverse US Hispanic/Latino adults, the prevalence of a LR profile is low. Lower acculturation is associated with higher odds of a LR profile among women but not men. Comprehensive public health strategies are needed to improve the cardiovascular health of US Hispanic/Latino adults

High Cholesterol Awareness, Treatment, and Control Among Hispanic/Latinos: Results From the Hispanic Community Health Study/Study of Latinos

BackgroundWe assessed high cholesterol (HC) awareness, treatment, and control rates among US Hispanic/Latino adults and describe factors associated with HC awareness and management.Methods and ResultsBaseline data (collected 2008–2011) from a multisite probability sample of Hispanic/Latino adults in the Hispanic Community Health Study/Study of Latinos (18 to 74years old; N=16207) were analyzed. HC was defined as low-density lipoprotein-cholesterol ≥130mg/dL and/or total cholesterol ≥240mg/dL or use of cholesterol-lowering medication. Among Hispanic/Latino adults with HC, almost half (49.3%) were not aware of their condition and only 29.5% were receiving treatment. Men had a higher HC prevalence than women (44.0% versus 40.5%) but a lower rate of treatment (28.1% versus 30.6%). Younger adults were significantly less likely to be HC aware compared to those who were older. Those with hypertension, diabetes, and high socioeconomic position were more likely to be HC aware. US-born Hispanic/Latino were more likely to be HC unaware than foreign-born Hispanics/Latinos, but longer US residency was significantly associated with being HC aware, treated, and controlled. Cholesterol control was achieved among 64.3% of those who were HC treated. However, younger adults, women, those with lower income, those uninsured, and more recent immigrants were less likely to be HC controlled. Individuals of Puerto Rican or Dominican background were most likely to be HC aware and treated, whereas those of Mexican or Central American background were least likely to be HC treated. Individuals of Cuban and South American background had the lowest rates of HC control, whereas Puerto Ricans had the highest.ConclusionsUnderstanding gaps in HC awareness, treatment, and control among US Hispanic/Latino adults can help inform physicians and policymakers to improve disease management and patient education programs