5 research outputs found

    Correlations between endocannabinoid and leptin concentrations and the corresponding parameters for age, BMI, AEA and 2-AG.

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    <p>Values are Spearman’s ρ, in deference to the non-normal distribution of serum 2-AG in the sample. The other parameters passed the D'Agostino & Pearson omnibus normality test. Significant correlations are shown in boldface.</p><p>Correlations between endocannabinoid and leptin concentrations and the corresponding parameters for age, BMI, AEA and 2-AG.</p

    Relationship between endocannabinoid and leptin levels in the serum (A, B) and CSF (C, D).

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    <p>Shown are the data for AEA (Panels A, C) and 2-AG (Panels B, D). The Spearman ρ values are provided in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0123132#pone.0123132.t002" target="_blank">Table 2</a>.</p

    Literature values of AEA and 2-AG (+1-AG) levels in the CSF.

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    <p><sup>a</sup>Means ± SD;</p><p><sup>b</sup>means ±SE;</p><p><sup>c</sup>values not given explicitly in the text but estimated from the figures;</p><p><sup>d</sup>refers to samples analysed for AEA and 2-AG, respectively.</p><p>Abbreviations: 1 °G and 2 °G, first- and second-generation, respectively; AD, Alzheimer’s disease; IQR, interquartile range; MS, multiple sclerosis; PAOH, probable analgesic overuse headache; PD, Parkinson’s disease.</p><p>All values are in pmol/ml.</p><p>Literature values of AEA and 2-AG (+1-AG) levels in the CSF.</p

    Characteristics of the study group stratified on the basis of gender (G) and incidence of diabetes (D).

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    <p>Data are given as medians with ranges, followed by the sample sizes in parentheses. Serum leptin levels are given as ng/ml while CSF leptin levels are given as pg/ml; serum AEA and 2-AG levels are given as ng/ml; and CSF AEA and 2-AG levels are given as pg/ml. P values are calculated using a non-parametric two-way robust Wilcoxon analysis [<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0123132#pone.0123132.ref038" target="_blank">38</a>]. Significant correlations are shown in boldface.</p><p>Characteristics of the study group stratified on the basis of gender (G) and incidence of diabetes (D).</p
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