262 research outputs found

    Right! From the Start: Improving Maternal-Child Health in the Mississippi Delta

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    Right! From the Start (R!FTS) was created nearly ten years ago as a collaborative effort between Women and Children Health Initiatives, Inc. and the Community Foundation of Northwest Mississippi with support from the W.K. Kellogg Foundation (WKKF). The immediate goal of the initiative was to raise breastfeeding rates for mothers and babies in vulnerable families, especially those with preterm and low weight births. A long-term goal was improvement of maternal and child health outcomes in a region plagued by socioeconomic and racial disparities, the Mississippi Delta. R!FTS has gone through three distinct phases of development, which are detailed in this article

    Notes from the Editorial Office (Volume 35, Issue 2)

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    As the year 2020 draws to a close, we are pleased to share this collection of articles in Volume 35, issue 2 of the Journal of Rural Social Sciences (JRSS). Addressing topics including energy, sustainable agriculture, well-being among aging populations, and survey methods, they showcase the scholarly rural-focused work important for shaping the future

    Nurses\u27 Alumnae Association Bulletin, December 1968

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    President\u27s Message Officers and Committee Chairman Financial Report Report to Alumnae Association Annual Report to Alumnae Association School of Practical Nursing Report Student Activities Nursing Service Staff Association Letter from Vietnam Resume of Alumnae Meetings Ways and Means Report Social Committee Building Fund Report Bulletin Committee Report Class News Notice

    Quantitative molecular assessment of chimerism across tissues in marmosets and tamarins

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    <p>Abstract</p> <p>Background</p> <p>Marmosets are playing an increasingly large and important role in biomedical research. They share genetic, anatomical, and physiological similarities with humans and other primate model species, but their smaller sizes, reproductive efficiency, and amenability to genetic manipulation offer an added practicality. While their unique biology can be exploited to provide insights into disease and function, it is also important that researchers are aware of the differences that exist between marmosets and other species. The New World monkey family Callitrichidae, containing both marmoset and tamarin species, typically produces dizygotic twins that show chimerism in the blood and other cells from the hematopoietic lineage. Recently, a study extended these findings to identify chimerism in many tissues, including somatic tissues from other lineages and germ cells. This has raised the intriguing possibility that chimerism may play an increasingly pervasive role in marmoset biology, ranging from natural behavioral implications to increased variability and complexity in biomedical studies.</p> <p>Results</p> <p>Using a quantitative PCR based methodology, Y-chromosomes can be reliably detected in the females with male fraternal twins allowing for a relative quantification of chimerism levels between individuals and tissues. With this approach in common marmosets (<it>Callithrix jacchus</it>) and cotton-top tamarins (<it>Saguinus oedipus</it>), chimerism was detected across a broad array of tissues. Chimerism levels were significantly higher in tissues primarily derived from the hematopoietic lineage, while they were lower, though still detectable, in tissues with other origins. Interestingly, animals with a characteristic marmoset wasting disease show higher levels of chimerism in those tissues affected. Fibroblast cell lines from chimeric individuals, however, are not found to be chimeric themselves.</p> <p>Conclusion</p> <p>Taken together, the levels of chimerism in tissues of different origins coupled with other lines of evidence suggest that indeed only hematopoietic cell lineages are chimeric in callitrichids. The chimerism detected in other tissues is likely the result of blood or lymphocytic infiltration. Using molecular methods to detect chimerism in a tissue sample seems to have allowed a substantial increase in the ability to detect these minor cell populations.</p

    Antigonon leptopus invasion is associated with plant community disassembly in a Caribbean island ecosystem

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    Invasions by non-native plant species are widely recognized as a major driver of biodiversity loss. Globally, (sub-)tropical islands form important components of biodiversity hotspots, while being particularly susceptible to invasions by plants in general and vines in particular. We studied the impact of the invasive vine A. leptopus on the diversity and structure of recipient plant communities on the northern Caribbean island St. Eustatius. We used a paired-plot design to study differences in species richness, evenness and community structure under A. leptopus-invaded and uninvaded conditions. Community structure was studied through species co-occurrence patterns. We found that in plots invaded by A. leptopus, species richness was 40–50% lower, and these plots also exhibited lower evenness. The magnitude of these negative impacts increased with increasing cover of A. leptopus. Invaded plots also showed higher degrees of homogeneity in species composition. Species co-occurrence patterns indicated that plant communities in uninvaded plots were characterized by segregation, whereas recipient plant communities in invaded plots exhibited random co-occurrence patterns. These observations suggest that invasion of A. leptopus is not only associated with reduced species richness and evenness of recipient communities in invaded sites, but also with a community disassembly process that may reduce diversity between sites. Given that A. leptopus is a successful invader of (sub-)tropical islands around the globe, these impacts on plant community structure highlight that this invasive species could be a particular conservation concern for these systems

    Nurses\u27 Alumnae Association Bulletin, June 1970

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    Alumnae President\u27s Message Congratulations Alumni Association Portrait of Samuel D. Gross Officers and Chairmen of Committees Financial Report Progress of Jefferson 1969-1970 School of Nursing Annual Report School of Practical Nursing Report Emergency Department Patient Services Department Annual Luncheon Pictures Committee Reports Progress of the Alumnae Association Crossword Puzzle Missing Graduates Resume of Alumnae Meetings Minutes Class News Student Nurses Section Crossword Puzzle Answers Notice

    Nurses\u27 Alumnae Association Bulletin, June 1969

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    Alumnae President\u27s Message Officers and Chairmen Financial Report Progressive Changes at Jefferson School of Nursing Report Student Activities School of Practical Nursing Report Jefferson Expansion Report Clerk-Typist Report Committee Reports Resume of Alumnae Meetings Class News 1969 CLINIC Correspondence Notice

    Composite iron oxide–Prussian blue nanoparticles for magnetically guided T1-weighted magnetic resonance imaging and photothermal therapy of tumors

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    Theranostic nanoparticles offer the potential for mixing and matching disparate diagnostic and therapeutic functionalities within a single nanoparticle for the personalized treatment of diseases. In this article, we present composite iron oxide-gadolinium-containing Prussian blue nanoparticles (Fe3O4@GdPB) as a novel theranostic agent for T1-weighted magnetic resonance imaging (MRI) and photothermal therapy (PTT) of tumors. These particles combine the well-described properties and safety profiles of the constituent Fe3O4 nanoparticles and gadolinium-containing Prussian blue nanoparticles. The Fe3O4@GdPB nanoparticles function both as effective MRI contrast agents and PTT agents as determined by characterizing studies performed in vitro and retain their properties in the presence of cells. Importantly, the Fe3O4@GdPB nanoparticles function as effective MRI contrast agents in vivo by increasing signal:noise ratios in T1-weighted scans of tumors and as effective PTT agents in vivo by decreasing tumor growth rates and increasing survival in an animal model of neuroblastoma. These findings demonstrate the potential of the Fe3O4@GdPB nanoparticles to function as effective theranostic agents

    Alumnae Association Bulletin of the School of Nursing, 1973

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    Alumnae Calendar The President\u27s Message Officers and Chairmen of Committees Financial Report Annual Reports Named to Academy of Nursing Alumnae Association Relief Fund Benefits Sesquicentennial - A Celebration and a Challenge Progress of the Thomas Jefferson University Hospital 1972-1973 Report of the Patient Services Department Changes in the Department of Radiation Therapy Annual Luncheon Committee Reports Administration Missing Alumnae Members Salute to Life Members The Class of 1973 Ways and Means Committee Report Resume of Minutes of Alumnae Association Meetings Class Notes Marriages Births In Memoriam Notice

    Nurses\u27 Alumnae Association Bulletin, June 1967

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    President\u27s Message Officers and Committee Chairman Financial Report Report to Alumnae Association Nursing Service Report Operating Room Report School of Practical Nursing Report School of Nursing Report President Herbert\u27s Address (abstracted) Report from Africa Student Activities Nursing Service Staff Association Resume of Alumnae Meetings Way and Means Report Social Committee Building Fund Report Class News Notice
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