Quintessence of Truth and Beauty in the Writings of Rabindranath Tagore and Keats A Comparative Analysis

In literary works, truth and beauty have been expressed in a varied number of ways by authors of all genres. Rabindranath Tagore and John Keats, two prominent writers from two languages have linked beauty and truth in philosophical manners in many of their writings. Beauty and truth are not separate entities; they flow from the same spring. Tagore views beauty as linked to eternal characteristics of nature and truth is associated with it. Keats sees beauty from spiritual perspective and according to him, realization of truth leads to the fulfillment of beauty. Readers of Tagore and Keats get eye-opening insights from the viewpoints that are followed by their expressions in regarding the tenets of truth and beauty. Truth and beauty fulfill each other in their harmonious existence in the universe. The authors make us realize that beauty does not emanate merely from sensual pleasure; it is an abstract idea, a spiritual understanding that originates from rhythmic attachment with truth. This article compares and contrasts philosophies of truth and beauty from the writings of Tagore and Keats. In doing so, the paper investigates the literary works of the two writers and explores how they have philosophized truth and beauty in the domain of human thought as well as in the realm of spiritual discipline

Variant anatomy of common hepatic artery and its branching pattern: a cadaveric study with clinical implication

Background: With the advent of new diagnostic, therapeutic and operative techniques within the abdominal cavity, a sound knowledge of the variant courses of the abdominal vessels become important for dealing clinicians, surgeons and interventional radiologists. Surgeons undertaking hepatobiliary and gastric surgery must be acquainted with the anatomy of common hepatic artery and should be able to recognize its multiple anatomical variants to avoid subsequent thrombosis leading to ischaemia of the liver or bile duct and stomach with distressing consequences. The present study was carried out to document the normal anatomy and different variations of the common hepatic artery and to evaluate the possible clinical implications.Methods: A total of 36 properly embalmed and formalin fixed cadavers were dissected in the abdominal region and viscera were mobilized to expose the origin of important branches of the common hepatic artery.Results: Classical branching pattern of common hepatic artery was seen in 91.66% cases. Origin of right hepatic artery from superior mesenteric artery and accessory cystic artery from gastroduodenal artery was seen in 2.77% cases. In 5.55% cases, right gastric artery originated from left hepatic artery.Conclusions: Knowledge of such variations will play a significant role in avoiding technical difficulties during infusion therapy and chemoembolization of neoplasm in the liver. It is also valuable in carrying out surgical intervention safely in the abdomen and also in the interpretation of angiographic reports

Effects of adenine sulphate, glutamine and casein hydrolysate on in vitro shoot multiplication and rooting of Kinnow mandarin (Citrus reticulata Blanco)

In vitro shoot regeneration was carried out for Kinnow mandarin (Citrus reticulata Blanco) through shoot tip explants obtained from in vitro germinated seedling. The medium supplemented with 2.5 mg/L benzylaminopurine (BAP) supported maximum shoot proliferation (2.45 shoots/explant). This rate was further enhanced (7.23 shoots/explant) by adding 25 mg/L glutamine, 50 mg/L adenine sulphate and 100 mg/L casein hydrolysate. From the in vitro proliferated shoots, the shoot apices and nodes were excised and sub-cultured on four different medium namely: SCM-1, SCM-2, SCM-3 and SCM-4 for six consecutive months. Problems like defoliation, chlorosis and loss of vigour in shoots were observed at different stages of subculture. These problems were successfully controlled by SCM-4 having 1.5 mg/L of BAP, 0.5% charcoal, 25 mg/L glutamine, 50 mg/L adenine sulphate and 100 mg/L casein hydrolysate. The SCM-4 also maintained the high proliferation rate throughout the subculturing process. Rooting was best induced on 2 mg/L indole-butyric acid (IBA) in combination with 0.1 mg/L indole-3-acetic acid (IAA). Rooting was significantly enhanced by 100 mg/L casein hydrolysate. The in vitro raised plantlets were acclimatized under culture room conditions in different potting mixture, of which the combination of garden soil, sand and vermiculite mixture in 1:1:2 ratio was found most supportive. After 30 days of acclimatization, plantlets were transferred to soil, where established plants  showed more than 90% survival.Key words: In vitro shoot regeneration, micro-shoots, enhanced shoot multiplication, subculture, acclimatization

Utjecaj fluorida proizvedenih aluminijskim industrijskim postrojenjem na biljke i područja nastanjena ljudima

Fluorine is a highly reactive common element that does not occur in nature in the elemental state. It exists in the form of fluorides and accounts for about 0.3 g/kg of the Earth’s crust. Generally, it is found in the form of a number of minerals like fluorspar, cryolite and fluor-apatite. Fluoride has both positive and negative effects on individual health. Fluoride, in the form of fluorspar and cryo- lite is distributed extensively in the lithosphere, and is renowned as the thir- teenth most common among elements in the earth’s crust. Hydrogen fluorides in gaseous form accumulate in the leaves of generally sensitive plants against a concentration gradient and therefore, considered as a most phytotoxic air pollut- ant and affects plants at extremely low concentration. As per our study, it is found that the fluoride impacts on fauna are in normal condition, but in coming times it may have adverse impact on fauna and flora of surroundings of Hindalco Industries Limited.Fluor je vrlo reaktivan element koji se u elementarnom obliku ne pojavljuje u prirodi. Postoji u obliku fluorida u zemljinoj kori, gdje se nalazi u omjeru od oko 0,3 g/kg. Općenito, nalazi se u obliku velikog broja minerala poput fluorita, kriolita i apatita. Fluorid ima i pozitivne i negativne učinke na ljudsko zdravlje. Fluorid, u obliku fluorita i kriolita, široko je rasprostranjen u litosferi, a poznat je i kao trinaesta najčešća tvar u Zemljinoj kori. Fluorovodici u plinovitom obliku nagomilavaju se u listovima uglavnom osjetljivih biljaka prema gradijentu koncentracije. Stoga se smatraju najfitotoksičnijim onečišćujućim tvarima u zraku, a djeluju na biljke i pri ekstremno niskim koncentracijama. Prema našoj studiji utvrđeno je da su učinci fluorida na faunu u uobičajenim okvirima, ali u budućnosti može imati štetan utjecaj na faunu i floru u okruženju tvornice Hindalco Industries Limited

Trend of Mortality by Water Related Intestinal infectious Diseases: A Study of National Capital Territory of Delhi, (2001 to 2011)

National Capital Territory (NCT) of Delhi is experiencing rapid urbanization for the last few decades. The area is lagging behind in water and waste management infrastructure. This is due to the fact that Delhi is recording high growth rate of population mostly through in-migration over the year which is taxing much upon the existing water resources and the provisions made for water supply. Consequently demand is higher than supply of the safe drinking water. The consumption of unsafe drinking water is therefore increasing and is causing serious health problems among the fellow residents of NCT of Delhi. These health problems are basically related to the digestive as well as excretory systems of the human body. These disorders are promoting mortality particularly among those segments of population which do not have access to potable drinking water. This paper is therefore a modest attempt towards examining the population growth rate and the scenarios of demand and supply for potable water as well as the overall water related intestinal infections and related mortality at present and their future occurrence. This requires synergy between the different sectors of the state to overcome the problem. of intestinal infection diseases in the region

Treatment of septage using lab-scale hybrid constructed wetland system

A lab based hybrid constructed wetland system (1.645 m2) consisting of sludge drying bed (0.135 m2), vertical sub-surface flow bed (0.58 m2), and horizontal sub-surface flow bed (0.93 m2) was operated for the treatment of septage. All the beds were filled with gravels of varied sizes (5-40 mm), sand (0.25 mm) and planted with Canna indica L. Average concentration in influent and effluent was observed as; BOD5 (2395.6±1196.4 and 41.87±8.9 mg/L), COD (7442± 7342.6 and 29.6±7.6 mg/L), TSS (4965.9±801.69 and 336.1±152.9 mg/L), TN (1774.8±693.5 and 55.7±13.7 mg/L), and Total P (849.3±237.7 and 7.05±3.5mg/L) during study period. Hybrid System was operated with high influent loads of BOD5 (175.2± 87.5 g m-2 d-1), COD (544.5±537 g m-2 d-1), TSS (363.3±58.6 g m-2 d-1), Total N (129.8±50.7 g m-2 d-1), NH4-N (7.8±1.1 g m-2 d-1), and Total P (62.1±17.4 g m-2 d-1), throughout the study period. Hybrid-CW has showed significant removal of BOD5 (99.1±0.3%), COD (99.7±0.3%), TS (98.2±6.8%), TSS (96.9±4.9%), Total N (98.4±0.4 %), NH4-N (94.8±0.1%), and Total P (99.6±0.1%) from the septage. Finally treated septage met effluent discharge standards for all parameters except BOD5

Characterization of 10-hydroxygeraniol dehydrogenase from Catharanthus roseus reveals cascaded enzymatic activity in iridoid biosynthesis

Catharanthus roseus [L.] is a major source of the monoterpene indole alkaloids (MIAs), which are of significant interest due to their therapeutic value. These molecules are formed through an intermediate, cis-trans-nepetalactol, a cyclized product of 10-oxogeranial. One of the key enzymes involved in the biosynthesis of MIAs is an NAD(P)+ dependent oxidoreductase system, 10-hydroxygeraniol dehydrogenase (Cr10HGO), which catalyses the formation of 10-oxogeranial from 10-hydroxygeraniol via 10-oxogeraniol or 10-hydroxygeranial. This work describes the cloning and functional characterization of Cr10HGO from C. roseus and its role in the iridoid biosynthesis. Substrate specificity studies indicated that, Cr10HGO has good activity on substrates such as 10-hydroxygeraniol, 10-oxogeraniol or 10-hydroxygeranial over monohydroxy linear terpene derivatives. Further it was observed that incubation of 10-hydroxygeraniol with Cr10HGO and iridoid synthase (CrIDS) in the presence of NADP+ yielded a major metabolite, which was characterized as (1R, 4aS, 7S, 7aR)-nepetalactol by comparing its retention time, mass fragmentation pattern and co-injection studies with that of the synthesized compound. These results indicate that there is concerted activity of Cr10HGO with iridoid synthase in the formation of (1R, 4aS, 7S, 7aR)-nepetalactol, an important intermediate in iridoid biosynthesis

Unravelling key genes associated with ovine Brucellosis by differential gene expression analysis: A holistic bioinformatics study

Ovine Brucellosis, caused by Brucella ovis bacteria, is a pathognomonic reproductive infectious disease of sheep that causes epididymitis in rams (male sheep) and placental inflammation in ewes (female sheep) leading to reduced fertility. The specific molecular process that causes alterations in genome of sheep during brucellosis is not yet fully understood. This study aimed to identify key host genes associated with the pathogenesis of ovine brucellosis caused by B. ovis. The GSE35614 dataset containing six healthy and six Brucella ovis infected sample of rams in the chronic phase 2 was obtained from the NCBI GEO database to examine and detect any differences in gene expression (DEGs). Functional and pathway enrichment analyse of the DEGs were performed along with the construction of protein-protein interaction network. Next, functional modules and hub genes were clustered and identified respectively, using the MCODE plugin. As a result, a total of 316 differentially expresses genes were filtered according to the provided cut-off criteria. The enriched DEGs were related to extracellular matrix interaction, cell adhesion mediated by integrin, angiogenesis, and inflammatory response. Furthermore, the hub gene analysis resulted in five hub genes namely, FN1, FBN1, CDH1, CD44, and SPP1, were up-regulated during the infection which could lead to reproductive disorders in sheep. In conclusion, the DEGs, functional and pathways terms, along with hub genes identified in the current study can provide prospective targets for the early diagnosis and treatment of brucellosis and provide insight into the molecular mechanism underlying the alterations that occur during brucellosis in sheep

Phylogeography of mtDNA haplogroup R7 in the Indian peninsula.

BACKGROUND: Human genetic diversity observed in Indian subcontinent is second only to that of Africa. This implies an early settlement and demographic growth soon after the first 'Out-of-Africa' dispersal of anatomically modern humans in Late Pleistocene. In contrast to this perspective, linguistic diversity in India has been thought to derive from more recent population movements and episodes of contact. With the exception of Dravidian, which origin and relatedness to other language phyla is obscure, all the language families in India can be linked to language families spoken in different regions of Eurasia. Mitochondrial DNA and Y chromosome evidence has supported largely local evolution of the genetic lineages of the majority of Dravidian and Indo-European speaking populations, but there is no consensus yet on the question of whether the Munda (Austro-Asiatic) speaking populations originated in India or derive from a relatively recent migration from further East. RESULTS: Here, we report the analysis of 35 novel complete mtDNA sequences from India which refine the structure of Indian-specific varieties of haplogroup R. Detailed analysis of haplogroup R7, coupled with a survey of approximately 12,000 mtDNAs from caste and tribal groups over the entire Indian subcontinent, reveals that one of its more recently derived branches (R7a1), is particularly frequent among Munda-speaking tribal groups. This branch is nested within diverse R7 lineages found among Dravidian and Indo-European speakers of India. We have inferred from this that a subset of Munda-speaking groups have acquired R7 relatively recently. Furthermore, we find that the distribution of R7a1 within the Munda-speakers is largely restricted to one of the sub-branches (Kherwari) of northern Munda languages. This evidence does not support the hypothesis that the Austro-Asiatic speakers are the primary source of the R7 variation. Statistical analyses suggest a significant correlation between genetic variation and geography, rather than between genes and languages. CONCLUSION: Our high-resolution phylogeographic study, involving diverse linguistic groups in India, suggests that the high frequency of mtDNA haplogroup R7 among Munda speaking populations of India can be explained best by gene flow from linguistically different populations of Indian subcontinent. The conclusion is based on the observation that among Indo-Europeans, and particularly in Dravidians, the haplogroup is, despite its lower frequency, phylogenetically more divergent, while among the Munda speakers only one sub-clade of R7, i.e. R7a1, can be observed. It is noteworthy that though R7 is autochthonous to India, and arises from the root of hg R, its distribution and phylogeography in India is not uniform. This suggests the more ancient establishment of an autochthonous matrilineal genetic structure, and that isolation in the Pleistocene, lineage loss through drift, and endogamy of prehistoric and historic groups have greatly inhibited genetic homogenization and geographical uniformity.RIGHTS : This article is licensed under the BioMed Central licence at http://www.biomedcentral.com/about/license which is similar to the 'Creative Commons Attribution Licence'. In brief you may : copy, distribute, and display the work; make derivative works; or make commercial use of the work - under the following conditions: the original author must be given credit; for any reuse or distribution, it must be made clear to others what the license terms of this work are